Lymphocyte immunization therapy (LIT) in reproductive failures : new horizons / Mohan Raut, Mugdha Raut.
Raut, Mohan, author.; Raut, Mugdha, author.
2022
RG201
Available Online

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Title Lymphocyte immunization therapy (LIT) in reproductive failures : new horizons / Mohan Raut, Mugdha Raut.
Author Raut, Mohan, author.
ISBN 9789811929601 (electronic bk.)
9811929602 (electronic bk.)
9789811929595
9811929599
DOI https://doi.org/10.1007/978-981-19-2960-1
Published Singapore : Springer, 2022.
Language English
Description 1 online resource (1 volume) : illustrations (black and white, and color).
Item Number 10.1007/978-981-19-2960-1 doi
Call Number RG201
Dewey Decimal Classification 618.1/7806
Summary Recurrent Miscarriages (RM) & Implantation Failure (IF) have remained an enigma to clinicians and researchers. Even after ruling out all possible causative factors, 50-60% cases still remain "Unexplained." A majority of these so called "Unexplained" cases are now found to have immunological basis. This book is going into the Immunological aspects of these clinical dilemmas, demystifying the role of Immunology and Immunotherapy in RM and IF. The authors have been working in the field of Reproductive Immunology and Immunotherapy for the last 25 years and they have come out with this book combining the international studies with their own experience. The purpose of writing this book is to provide a comprehensive treatise about Immunotherapy, so that it can become an acceptable modality of treatment in cases where it is needed and is effective. The book discusses the basics in Reproductive Immunology. The immunological changes occurring during pregnancy, the role of Cell mediated Immunity (T cells), Humoral Immunity including cytokines is explained. The normal immunological mechanisms protecting the embryo are highlighted and how these mechanisms are disturbed leading to RM and IF, is also explained. The first and the most discussed method of Immunotherapy is Lymphocyte Immunization Therapy (LIT). The book has given a complete overview of LIT, describing how it created euphoria when it was first introduced, how it gradually went into disrepute and how it is now making a comeback. As the authors have personal experience of LIT, the book gives a detailed and complete information about this active form of immunotherapy. The book has a special section on case studies where the authors have given some clinical case reports (including some of their own), who were treated for immunological factor in RM/IF and were treated with Immunotherapy. These cases can be a useful guide to the readers. The book will be useful not only for undergraduate and postgraduate students but also for clinicians in their practice and for researchers for review of developments in the field.
Bibliography, etc. Note Includes bibliographical references.
Access Note Access limited to authorized users.
Source of Description Description based on print version record.
Added Author Raut, Mugdha, author.
Available in Other Form Lymphocyte immunization therapy (LIT) in reproductive failures.
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Record Appears in Online Resources > Ebooks
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Part I
Chapter 1: Introduction
Chapter 2: Recurrent Pregnancy Loss and Recurrent Implantation Failure
Chapter 3: Immune System
Chapter 4: Immunology of Pregnancy (Reproductive Immunology)
Chapter 5: Diagnosis of Alloimmune factor
Part II
Chapter 6: Introduction
Chapter 7: History of LIT
Chapter 8: Mechanism of Action of LIT
Chapter 9: Procedure of LIT
Chapter 10: Safety of LIT
Chapter 11: Controversies about LIT REMIS Study
Chapter 12: Cochrane Reviews & LIT
Chapter 13: Recent Meta-analyses & LIT
Chapter 14: Review of International studies of LIT
Chapter 15: Case Studies
Chapter 16: Future of LIT.

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