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Table of Contents
Intro
Foreword by Dr. Soumitra Kumar Choudhuri
Foreword by Prof. Pranab Sarkar
Preface
Contents
Introduction to Quantum Dots
References
Synthetic Developments of Semiconductor Quantum Dot for Biological Applications
1 Introduction
2 Classification of QDs by Their Composition
2.1 Core Type QDs
2.2 Core-Shell Type QDs
2.3 Alloyed Shell Type QDs
3 Synthetic Strategies
3.1 Physicochemical Principles of Nucleation and Growth
3.2 Chemistry of the Inorganic Core, Interaction with Organic Surface Ligands
4 Surface Modification of QDs for Biological Applications
4.1 Surface Coating
4.2 Encapsulation of Amphiphilic Ligands
4.3 Multidentate Ligands for Ligands Exchange
5 Conclusion
References
All-Optical Detection of Biocompatible Quantum Dots
1 Introduction
2 Basic Properties of QDs
3 Optical Techniques for the Detection of QDs
3.1 Absorption and Emission Spectroscopy
3.2 Fluorescence Microscopy
3.3 Dynamic Light Scattering (DLS) Technology
3.4 FTIR Spectroscopy
3.5 Raman Spectroscopy
4 Conclusion
References
A Toxicologic Review of Quantum Dots: Recent Insights and Future Directions
1 Introduction
2 General Comments on the Toxicity of QDs
2.1 Identifying Hazards
2.2 Routes of Exposure to QDs
2.3 Factors Affecting NPs-Cell Interactions
2.4 Mechanisms of Cellular and Tissue Transport of QDs
2.5 Dose Assessment for Nanotoxicology
2.6 The Biological Relevance of Nanotoxicology
2.7 Nanotoxicity Assessment
3 Strategies to Mitigate the Toxicity of QDs
4 Conclusion and Future Perspectives
References
Advantages and Disadvantages of Using Quantum Dots in Lateral Flow and Other Biological Assay Formats
1 Introduction
2 Quantum Dot Use in Biological and Diagnostic Assays
2.1 Advantages of Quantum Dots
2.2 Disadvantages of Quantum Dots and Remedies
3 Discussion
4 Conclusions
References
Recent Developments in Quantum Dots Technologies as Effective Theranostic Tools Against Cancer
1 Introduction
2 Cancer: Selective Types and Properties
2.1 Breast Cancer
2.2 Liver Cancer
2.3 Gastric Cancer
2.4 Lung Cancer
3 Nanoparticles Used in Cancer Therapy: Focus on Quantum Dots
3.1 Inorganic Quantum Dots
3.2 Magnetic Quantum Dots or Magnetic Nanoparticles
3.3 Organic Quantum Dots
4 Conclusion
References
The Underlying Mechanism of Quantum Dot-Induced Apoptosis: Potential Application in Cancer Therapy
1 Introduction
2 Properties of QDs
3 Apoptosis: A Basic Biological Phenomenon
3.1 Characteristics of Cell Apoptosis
3.2 Intrinsic and Extrinsic Apoptotic Pathways
4 Applications of QDs and Their Potential Toxicity
4.1 Quantum Dots Induced Cell Death
Foreword by Dr. Soumitra Kumar Choudhuri
Foreword by Prof. Pranab Sarkar
Preface
Contents
Introduction to Quantum Dots
References
Synthetic Developments of Semiconductor Quantum Dot for Biological Applications
1 Introduction
2 Classification of QDs by Their Composition
2.1 Core Type QDs
2.2 Core-Shell Type QDs
2.3 Alloyed Shell Type QDs
3 Synthetic Strategies
3.1 Physicochemical Principles of Nucleation and Growth
3.2 Chemistry of the Inorganic Core, Interaction with Organic Surface Ligands
4 Surface Modification of QDs for Biological Applications
4.1 Surface Coating
4.2 Encapsulation of Amphiphilic Ligands
4.3 Multidentate Ligands for Ligands Exchange
5 Conclusion
References
All-Optical Detection of Biocompatible Quantum Dots
1 Introduction
2 Basic Properties of QDs
3 Optical Techniques for the Detection of QDs
3.1 Absorption and Emission Spectroscopy
3.2 Fluorescence Microscopy
3.3 Dynamic Light Scattering (DLS) Technology
3.4 FTIR Spectroscopy
3.5 Raman Spectroscopy
4 Conclusion
References
A Toxicologic Review of Quantum Dots: Recent Insights and Future Directions
1 Introduction
2 General Comments on the Toxicity of QDs
2.1 Identifying Hazards
2.2 Routes of Exposure to QDs
2.3 Factors Affecting NPs-Cell Interactions
2.4 Mechanisms of Cellular and Tissue Transport of QDs
2.5 Dose Assessment for Nanotoxicology
2.6 The Biological Relevance of Nanotoxicology
2.7 Nanotoxicity Assessment
3 Strategies to Mitigate the Toxicity of QDs
4 Conclusion and Future Perspectives
References
Advantages and Disadvantages of Using Quantum Dots in Lateral Flow and Other Biological Assay Formats
1 Introduction
2 Quantum Dot Use in Biological and Diagnostic Assays
2.1 Advantages of Quantum Dots
2.2 Disadvantages of Quantum Dots and Remedies
3 Discussion
4 Conclusions
References
Recent Developments in Quantum Dots Technologies as Effective Theranostic Tools Against Cancer
1 Introduction
2 Cancer: Selective Types and Properties
2.1 Breast Cancer
2.2 Liver Cancer
2.3 Gastric Cancer
2.4 Lung Cancer
3 Nanoparticles Used in Cancer Therapy: Focus on Quantum Dots
3.1 Inorganic Quantum Dots
3.2 Magnetic Quantum Dots or Magnetic Nanoparticles
3.3 Organic Quantum Dots
4 Conclusion
References
The Underlying Mechanism of Quantum Dot-Induced Apoptosis: Potential Application in Cancer Therapy
1 Introduction
2 Properties of QDs
3 Apoptosis: A Basic Biological Phenomenon
3.1 Characteristics of Cell Apoptosis
3.2 Intrinsic and Extrinsic Apoptotic Pathways
4 Applications of QDs and Their Potential Toxicity
4.1 Quantum Dots Induced Cell Death