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001450395 001__ 1450395
001450395 003__ OCoLC
001450395 005__ 20230310004523.0
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001450395 008__ 221017s2022\\\\si\a\\\\o\\\\\000\0\eng\d
001450395 019__ $$a1346533489$$a1347026078
001450395 020__ $$a9789811678974$$q(electronic bk.)
001450395 020__ $$a9811678979$$q(electronic bk.)
001450395 020__ $$z9811678960
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001450395 0247_ $$a10.1007/978-981-16-7897-4$$2doi
001450395 035__ $$aSP(OCoLC)1347731114
001450395 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dYDX$$dEBLCP$$dOCLCF$$dUKAHL$$dOCLCQ
001450395 049__ $$aISEA
001450395 050_4 $$aRM666.P87
001450395 08204 $$a615.3$$223/eng/20221017
001450395 24500 $$aTherapeutic proteins against human diseases /$$cFahmida Khatoon Zahid Balouch, editor.
001450395 264_1 $$aSingapore :$$bSpringer,$$c2022.
001450395 300__ $$a1 online resource :$$billustrations (color).
001450395 336__ $$atext$$btxt$$2rdacontent
001450395 337__ $$acomputer$$bc$$2rdamedia
001450395 338__ $$aonline resource$$bcr$$2rdacarrier
001450395 5050_ $$aProteins drug targeting and its therapeutics -- Interferons -- Epidermal growth factor (egf) in wound repair -- Therapeutic protein against autoimmune disorders: Intracellular and extracellular properties -- Prions as Therapeutic proteins and their Prospect as Drug Delivery Agent -- INTERLEUKIN - 2 -- Bioinformatics resources, tools, and strategies in designing therapeutic proteins -- Therapeutic proteins used in human pancreatic disease -- Therapeutic role of soybean-derived lunasin peptide in colon cancer treatment: A recent updates from literature -- Therapeutic peptides in skin and hair disorders. .
001450395 506__ $$aAccess limited to authorized users.
001450395 520__ $$aThis book compiles updated research about the implications of therapeutic proteins in various human diseases. The initial chapters of the book provide basic information on the therapeutic proteins and discuss techniques for their formulation, production, and analytic approaches for their characterization. The subsequent chapters shed light on therapies based on therapeutic proteins against metabolic disorders, neurological disorders, cancer, autoimmune disorders, and infectious diseases. Importantly, it presents the factors influencing the immunogenicity of therapeutic proteins, including, genetic factors, disease type, and origin of therapeutic protein, dose frequency, administration route, and treatment duration. The book also reviews the strategies for reducing immunogenicity associated with therapeutic proteins, including PEGylation, site specific mutagenesis, exon shuffling, and humanizing of monoclonal antibodies. Further, it presents strategies for improving the typical drawback associated with protein therapeutics including instability and limited penetration through biological barriers. This book covers various computational methods that are commonly used for designing therapeutic proteins and in silico method for predicting and improving in vivo efficacy of the therapeutic molecules. Lastly, the book highlights the recent advances in developing nanosized delivery systems to improve safety and efficacy of protein therapeutics. This book caters to students and researchers of medicinal chemistry, pharmaceutical sciences and therapeutics. It is also useful to clinicians working with therapeutic proteins.
001450395 588__ $$aDescription based on print version record.
001450395 650_0 $$aProtein drugs.
001450395 650_0 $$aProteins$$xTherapeutic use.
001450395 655_0 $$aElectronic books.
001450395 7001_ $$aZahid Balouch, Fahmida Khatoon,$$eeditor.
001450395 77608 $$iPrint version:$$tTHERAPEUTIC PROTEINS AGAINST HUMAN DISEASES.$$d[Place of publication not identified] : SPRINGER, 2022$$z9811678960$$w(OCoLC)1277281402
001450395 852__ $$bebk
001450395 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-981-16-7897-4$$zOnline Access$$91397441.1
001450395 909CO $$ooai:library.usi.edu:1450395$$pGLOBAL_SET
001450395 980__ $$aBIB
001450395 980__ $$aEBOOK
001450395 982__ $$aEbook
001450395 983__ $$aOnline
001450395 994__ $$a92$$bISE