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Table of Contents
Intro
Foreword by Dr. Zaver Bhujwalla
Foreword by Dr. Sachdeva
Foreword by Dr. Bo Fei
Preface
Contents
Imaging Modalities and Their Applications in Cancer Detection Using Nanomaterials
1 Introduction
1.1 History of Nanotechnology
1.2 Nanotechnological Applications
2 Imaging Modalities
2.1 Magnetic Resonance Imaging
2.1.1 Principles of MRI
2.1.2 Applications of Nanoparticles in MRI
2.2 Ultrasonography
2.2.1 Principles
2.2.2 Applications of Nanotechnology in Ultrasonography
2.3 CT Scan
2.3.1 Principles
2.4 PET Scan
2.4.1 Principles
2.5 PET-CT
2.5.1 Principles
2.6 Mammography
3 Nanoparticles for Computed Tomography (CT)
4 A Comparison of CT and MRI
5 Conclusion and Outlook
References
Nanoparticles for Enhanced Radiotherapy and Imaging Applications
1 Introduction
2 Radiotherapy Concepts
2.1 X-Ray Beam Radiotherapy
2.2 Proton Beam Therapy
2.3 Heavy Ion Beam Radiotherapy
2.4 Molecular Radiotherapy (Radioisotope/Radionuclide Therapy)
2.5 Enhancement of Radiotherapy Using Nanoparticles
3 Photodynamic Therapy (PDT)
4 Evolution of Photodynamic Therapy (PDT) to Deep PDT and Radiodynamic Therapy (RDT)
4.1 Deep/Near-Infrared (NIR) PDT
4.2 Nanoparticles for X-Ray Radiodynamic Therapy
4.3 Nanoparticles for Proton Radiodynamic Therapy (Proton RDT)
4.4 Ion Beam Radiodynamic Therapy (Ion Beam RDT)
5 Nanoparticle-Enhanced Molecular Radiotherapies
6 Tumour-Seeking Nanoparticles for Tumour Monitoring, Diagnostics, and Radiotherapy
6.1 Passive Targeting: Preferential Accumulation
6.2 Active Targeting via Ligand/Receptor Interactions
6.3 Crossing Physiological Barriers
7 Conclusion
2.4.1 Applied Alternating Magnetic Field (Hac), Internal Energy, and Power Dissipation
2.4.2 Practical Approach for the Relationship to Material Properties
2.4.3 SAR and ILP Calculations
3 Experimental Methods
4 Magnetic Nanofluid Droplets (MNDs) for Cancer Detection and Therapeutics
4.1 Droplets for Cancer Diagnosis, Therapy, and Theranostics
4.2 MNDs for Cancer Therapy and Theranostics
4.3 Modified MNDs for Cancer Therapy and Theranostics
4.4 Drug-Loaded MNDs for Cancer Therapy and Theranostics
4.5 MNDs for Cancer Diagnosis
Foreword by Dr. Zaver Bhujwalla
Foreword by Dr. Sachdeva
Foreword by Dr. Bo Fei
Preface
Contents
Imaging Modalities and Their Applications in Cancer Detection Using Nanomaterials
1 Introduction
1.1 History of Nanotechnology
1.2 Nanotechnological Applications
2 Imaging Modalities
2.1 Magnetic Resonance Imaging
2.1.1 Principles of MRI
2.1.2 Applications of Nanoparticles in MRI
2.2 Ultrasonography
2.2.1 Principles
2.2.2 Applications of Nanotechnology in Ultrasonography
2.3 CT Scan
2.3.1 Principles
2.4 PET Scan
2.4.1 Principles
2.5 PET-CT
2.5.1 Principles
2.6 Mammography
3 Nanoparticles for Computed Tomography (CT)
4 A Comparison of CT and MRI
5 Conclusion and Outlook
References
Nanoparticles for Enhanced Radiotherapy and Imaging Applications
1 Introduction
2 Radiotherapy Concepts
2.1 X-Ray Beam Radiotherapy
2.2 Proton Beam Therapy
2.3 Heavy Ion Beam Radiotherapy
2.4 Molecular Radiotherapy (Radioisotope/Radionuclide Therapy)
2.5 Enhancement of Radiotherapy Using Nanoparticles
3 Photodynamic Therapy (PDT)
4 Evolution of Photodynamic Therapy (PDT) to Deep PDT and Radiodynamic Therapy (RDT)
4.1 Deep/Near-Infrared (NIR) PDT
4.2 Nanoparticles for X-Ray Radiodynamic Therapy
4.3 Nanoparticles for Proton Radiodynamic Therapy (Proton RDT)
4.4 Ion Beam Radiodynamic Therapy (Ion Beam RDT)
5 Nanoparticle-Enhanced Molecular Radiotherapies
6 Tumour-Seeking Nanoparticles for Tumour Monitoring, Diagnostics, and Radiotherapy
6.1 Passive Targeting: Preferential Accumulation
6.2 Active Targeting via Ligand/Receptor Interactions
6.3 Crossing Physiological Barriers
7 Conclusion
2.4.1 Applied Alternating Magnetic Field (Hac), Internal Energy, and Power Dissipation
2.4.2 Practical Approach for the Relationship to Material Properties
2.4.3 SAR and ILP Calculations
3 Experimental Methods
4 Magnetic Nanofluid Droplets (MNDs) for Cancer Detection and Therapeutics
4.1 Droplets for Cancer Diagnosis, Therapy, and Theranostics
4.2 MNDs for Cancer Therapy and Theranostics
4.3 Modified MNDs for Cancer Therapy and Theranostics
4.4 Drug-Loaded MNDs for Cancer Therapy and Theranostics
4.5 MNDs for Cancer Diagnosis