001450787 000__ 05385cam\a2200493\a\4500 001450787 001__ 1450787 001450787 003__ OCoLC 001450787 005__ 20230310004543.0 001450787 006__ m\\\\\o\\d\\\\\\\\ 001450787 007__ cr\un\nnnunnun 001450787 008__ 221031s2022\\\\sz\\\\\\o\\\\\001\0\eng\d 001450787 020__ $$a9783031076343$$q(electronic bk.) 001450787 020__ $$a3031076346$$q(electronic bk.) 001450787 020__ $$z3031076338 001450787 020__ $$z9783031076336 001450787 0247_ $$a10.1007/978-3-031-07634-3$$2doi 001450787 035__ $$aSP(OCoLC)1349309709 001450787 040__ $$aYDX$$beng$$cYDX$$dGW5XE$$dOCLCF$$dUKAHL 001450787 049__ $$aISEA 001450787 050_4 $$aRC268.4 001450787 08204 $$a616.994042$$223/eng/20221101 001450787 24500 $$aMetabolism and epigenetic regulation :$$bimplications in cancer /$$cTapas Kumar Kundu, Chandrima Das, editors. 001450787 260__ $$aCham, Switzerland :$$bSpringer,$$c2022. 001450787 300__ $$a1 online resource 001450787 4901_ $$aSubcellular Biochemistry,$$x2542-8810 ;$$vvolume 100 001450787 500__ $$aIncludes index. 001450787 5050_ $$aPart 1: Regulation Of Key Metabolic Pathways In Cancer -- Chapter 1: Reprogramming Carbohydrate Metabolism In Cancer And Its Role In Regulating The Tumor Microenvironment. Chapter 2: Iron In Cancer Progression: Does Bach1 Promote Metastasis By Altering Iron Homeostasis? -- Chapter 3: Regulation Of Lipid Metabolism Under Stress And Its Role In Cancer -- Chapter 4: Role Of The Histone Acetyl Transferase Mof And The Histone Deacetylase Sirtuins In Regulation Of H4k16ac During Dna Damage Repair And Metabolic Programming: Implications In Cancer And Aging -- Chapter 5: Autophagy In Cancer: A Metabolic Perspective -- Part 2: Epigenetic Regulation Of Cellular Metabolic Pathways -- Chapter 6: Long Noncoding Rnas; Lnc(Ing) Rna Metabolism, To Cancer Biology -- Chapter 7: Modulation Of Dna/Rna Methylation Signalling Mediating Metabolic Homeostasis In Cancer -- Chapter 8: Nutritional Epigenetics: How Metabolism Epigenetically Controls Cellular Physiology, Gene Expression And Disease -- Chapter 9: Epigenetic Reprogramming Of The Glucose Metabolic Pathways By The Chromatin Effectors During Cancer -- Chapter 10: Sirtuin 6 Is A Critical Epigenetic Regulator Of Cancer -- Chapter 11: Epigenetic Regulation During Hypoxia And Its Implications In Cancer -- Part 3: Epigenetic Regulation In Cancer -- Chapter 12: Metabolic Regulation Of Lysine Acetylation: Implications In Cancer -- Chapter 13: The Cross-Talk Between Epigenetic Gene Regulation And Signaling Pathways Regulates Cancer Pathogenesis -- Chapter 14: Epigenetic Regulation Towards Acquired Drug Resistance In Cancer -- Chapter 15: Structural Basis Of Targeted Imaging And Therapy In Cancer- Explorations With The Epigenetic Drugs -- Chapter 16: Epigenetic Small Molecule Modulators Targeting Metabolic Pathways In Cancer -- Chapter 17: Modulation Of Dna/Rna Methylation By Small Molecule Modulators And Their Implications In Cancer -- Chapter 18: Understanding The Cross-Talk Between Epigenetics And Immunometabolism To Combat Cancer. . 001450787 506__ $$aAccess limited to authorized users. 001450787 520__ $$aMetabolic programs of individuals are key determinants for disease susceptibility and immune response. This book, edited by experts in the field, summarizes epigenetic signaling pathways that regulate metabolic programs associated with cancer and cancer-related secondary diseases. The first part of the book highlights key metabolic pathways that are implicated in cancer and provides a comprehensive overview on the carbohydrate, protein, lipid, amino- and nucleic acid metabolic pathways that are deregulated in cancer. Special attention is paid to the altered tumor micro-environment that is influenced by the metabolic milieu. Furthermore, the fundamental relationship between the cellular metabolic environment and cell death-mediated autophagy is discussed. The second part of the book covers our understanding of the fundamental epigenetic regulations that are implicated in controlling the metabolic programs in cancer cells. Many aspects of epigenetic regulation of non-coding RNAs as well as DNA/RNA methylation, which influencing metabolic homeostasis in cancer, are discussed in detail. Special emphasis is placed on the epigenetic regulation of the amino acid, glucose/carbohydrate metabolism and epigenetic regulation during hypoxia and its connection to cancer. Last but not least, the third part of the book covers small molecule modulators of histone modifying enzymes, which can be used as therapeutic tools. The readers learn about the cross-talk between epigenetics and immunometabolims, as well as the epigenetic regulation of oncometabolites to combat cancer. Given its scope, the book will appeal to a broad readership interested in epigenetic, cancer and metabolic research. 001450787 588__ $$aOnline resource; title from PDF title page (Library Ideas, viewed Nov. 1, 2022). 001450787 650_0 $$aCancer$$xGenetic aspects. 001450787 650_0 $$aEpigenetics. 001450787 650_0 $$aGenetic regulation. 001450787 655_0 $$aElectronic books. 001450787 7001_ $$aKundu, Tapas K.,$$eeditor. 001450787 7001_ $$aDas, Chandrima,$$eeditor. 001450787 77608 $$iPrint version: $$z3031076338$$z9783031076336$$w(OCoLC)1317839599 001450787 830_0 $$aSub-cellular biochemistry ;$$vv. 100. 001450787 852__ $$bebk 001450787 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-031-07634-3$$zOnline Access$$91397441.1 001450787 909CO $$ooai:library.usi.edu:1450787$$pGLOBAL_SET 001450787 980__ $$aBIB 001450787 980__ $$aEBOOK 001450787 982__ $$aEbook 001450787 983__ $$aOnline 001450787 994__ $$a92$$bISE