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Table of Contents
1. Experimental methodologies involved in the discovery of drugs
2. Laboratory animals
3. Care and Handling of Laboratory Animals
4. Biological Sample Collection from Experimental Animals
5. Anaesthesia and Euthanasia of Experimental Animals
6. Equipment in experimental Pharmacology
7. Bioassay and experiments on isolated muscle preparations
8. Experiments on Anaesthetized Intact Animals
9. Bioassay of standard compounds
10. PRINCIPLES OF EC50, ED50, pD2 and pA2 VALUES OF DRUGS
11. Physiological salt solutions
12. Validation of animal model
13. Screening Methods for the Evaluation of Antidepressant Drugs
14. Screening methods for evaluation of antiepileptics
15. Screening Methods Involved in the Evaluation of General Anaesthetics
16. Screening methods for evaluation of anti-psychotics
17. Screening methods for evaluation of sedative and hypnotics
18. Screening Methods for the Evaluation of Anxiolytic Drugs
19. Screening methods for evaluation of drugs with Anti-Parkinsonism activities
20. Screening methods for evaluation of drugs for learning and memory
21. Screening Methods Involved in the Evaluation of Antianginal Agents
22. Screening methods involved in the evaluation of Anti-hypertensive agents
23. Screening methods involved in the evaluation of anti arrhythmic agents
24. Screening methods involved in evaluation of cardiotonic drugs (Cardiac Hypertrophy and Insufficiency/ Drugs for Heart Failure)
25. Screening Methods for the Evaluation of Antiplatelet Drugs
26. Screening methods involved in the evaluation of diuretics
27. Screening Methods for anti-hyperlipidemic agents
28. Screening Methods Involved in the Evaluation of Antiulcer Drugs
29. Screening Methods Involved in the Evaluation of Antidiarrheal Drugs (Drugs Affecting Intestinal Motility and Secretion)
30. Screening Methods Involved in the Evaluation of Antiemetics
31. Screening Methods for the Evaluation of Hepatoprotective Agents
32. Screening Methods for the Evaluation of Anti-obesity Drugs
33. Absorption studies
34. Screening methods for evaluation of anti-asthma agents
35. Screening Methods for Evaluation of Antitussives and Expectorants
36. Screening methods involved in the evaluation of anti-diabetic drugs
37. Screening Methods for the Evaluation of Antithyroid Drugs
38. Screening methods for evaluation of antifertility drugs
39. Screening methods for evaluation of Posterior Pituitary, Adrenal Steroid, Testicular, Parathyroid, Ovarian, and Thyroid Hormones
40. Screening methods involved in the evaluation of drugs with analgesic, anti-inflammatory, and antipyretic activity
41. Screening Methods Involved in the Evaluation of Drugs with Ophthalmologic Activity
42. SCREENING METHODS FOR THE EVALUATION OF DRUGS AFFECTING PERIPHERAL NERVE FUNCTION
43. MUTAGENIC TOXICITY TESTING
44. Screening methods for evaluation of anticancer drugs
45. Screening Methods Involved in the Evaluation of Drugs for Benign Prostatic Hyperplasia
46. Evaluation of Drugs Acting on Autonomic Nervous System
47. Screening Methods for the Evaluation of Antifungal, Anthelminthic, Antibacterial, and Antiviral Agents
48. Preclinical toxicity studies
49. Ethical Issues in Animal Research
50. Good Laboratory Practice (GLP)
51. Basic principles and applications of simple analytical methods
52. Principles of Quantitative Estimation of Drugs, Endogenous Compounds, and Poisons
53. Principles of quantitative estimation of drugs, endogenous compounds, and poisons - 2
54. Plant extraction methods
55. Literature search
56. STUDY DESIGNS
57. Ethical Issues Related to Medical Research on Human Participants
58. Basic principles and application of statistics in drug research
59. Calculation of Basic Statistical Parameters
60. Hypothesis Testing
61. Parametric tests
62. NON-PARAMETRIC TESTS
63. Common errors in using statistical tools and data presentation.
2. Laboratory animals
3. Care and Handling of Laboratory Animals
4. Biological Sample Collection from Experimental Animals
5. Anaesthesia and Euthanasia of Experimental Animals
6. Equipment in experimental Pharmacology
7. Bioassay and experiments on isolated muscle preparations
8. Experiments on Anaesthetized Intact Animals
9. Bioassay of standard compounds
10. PRINCIPLES OF EC50, ED50, pD2 and pA2 VALUES OF DRUGS
11. Physiological salt solutions
12. Validation of animal model
13. Screening Methods for the Evaluation of Antidepressant Drugs
14. Screening methods for evaluation of antiepileptics
15. Screening Methods Involved in the Evaluation of General Anaesthetics
16. Screening methods for evaluation of anti-psychotics
17. Screening methods for evaluation of sedative and hypnotics
18. Screening Methods for the Evaluation of Anxiolytic Drugs
19. Screening methods for evaluation of drugs with Anti-Parkinsonism activities
20. Screening methods for evaluation of drugs for learning and memory
21. Screening Methods Involved in the Evaluation of Antianginal Agents
22. Screening methods involved in the evaluation of Anti-hypertensive agents
23. Screening methods involved in the evaluation of anti arrhythmic agents
24. Screening methods involved in evaluation of cardiotonic drugs (Cardiac Hypertrophy and Insufficiency/ Drugs for Heart Failure)
25. Screening Methods for the Evaluation of Antiplatelet Drugs
26. Screening methods involved in the evaluation of diuretics
27. Screening Methods for anti-hyperlipidemic agents
28. Screening Methods Involved in the Evaluation of Antiulcer Drugs
29. Screening Methods Involved in the Evaluation of Antidiarrheal Drugs (Drugs Affecting Intestinal Motility and Secretion)
30. Screening Methods Involved in the Evaluation of Antiemetics
31. Screening Methods for the Evaluation of Hepatoprotective Agents
32. Screening Methods for the Evaluation of Anti-obesity Drugs
33. Absorption studies
34. Screening methods for evaluation of anti-asthma agents
35. Screening Methods for Evaluation of Antitussives and Expectorants
36. Screening methods involved in the evaluation of anti-diabetic drugs
37. Screening Methods for the Evaluation of Antithyroid Drugs
38. Screening methods for evaluation of antifertility drugs
39. Screening methods for evaluation of Posterior Pituitary, Adrenal Steroid, Testicular, Parathyroid, Ovarian, and Thyroid Hormones
40. Screening methods involved in the evaluation of drugs with analgesic, anti-inflammatory, and antipyretic activity
41. Screening Methods Involved in the Evaluation of Drugs with Ophthalmologic Activity
42. SCREENING METHODS FOR THE EVALUATION OF DRUGS AFFECTING PERIPHERAL NERVE FUNCTION
43. MUTAGENIC TOXICITY TESTING
44. Screening methods for evaluation of anticancer drugs
45. Screening Methods Involved in the Evaluation of Drugs for Benign Prostatic Hyperplasia
46. Evaluation of Drugs Acting on Autonomic Nervous System
47. Screening Methods for the Evaluation of Antifungal, Anthelminthic, Antibacterial, and Antiviral Agents
48. Preclinical toxicity studies
49. Ethical Issues in Animal Research
50. Good Laboratory Practice (GLP)
51. Basic principles and applications of simple analytical methods
52. Principles of Quantitative Estimation of Drugs, Endogenous Compounds, and Poisons
53. Principles of quantitative estimation of drugs, endogenous compounds, and poisons - 2
54. Plant extraction methods
55. Literature search
56. STUDY DESIGNS
57. Ethical Issues Related to Medical Research on Human Participants
58. Basic principles and application of statistics in drug research
59. Calculation of Basic Statistical Parameters
60. Hypothesis Testing
61. Parametric tests
62. NON-PARAMETRIC TESTS
63. Common errors in using statistical tools and data presentation.