001451386 000__ 04587cam\a2200505\a\4500 001451386 001__ 1451386 001451386 003__ OCoLC 001451386 005__ 20230310004657.0 001451386 006__ m\\\\\o\\d\\\\\\\\ 001451386 007__ cr\un\nnnunnun 001451386 008__ 221119s2022\\\\sz\\\\\\o\\\\\001\0\eng\d 001451386 019__ $$a1350866398 001451386 020__ $$a9783031148484$$q(electronic bk.) 001451386 020__ $$a3031148487$$q(electronic bk.) 001451386 020__ $$z3031148479 001451386 020__ $$z9783031148477 001451386 0247_ $$a10.1007/978-3-031-14848-4$$2doi 001451386 035__ $$aSP(OCoLC)1351201596 001451386 040__ $$aEBLCP$$beng$$cEBLCP$$dYDX$$dGW5XE$$dSFB$$dOCLCF$$dUKAHL$$dOCLCQ 001451386 049__ $$aISEA 001451386 050_4 $$aRC270.8 001451386 08204 $$a616.99/406$$223/eng/20221129 001451386 24500 $$aPolymeric nanoparticles for the treatment of solid tumors /$$cSantwana Padhi, Anindita Behera, Eric Lichtfouse, editors. 001451386 260__ $$aCham :$$bSpringer,$$c2022. 001451386 300__ $$a1 online resource (515 p.). 001451386 4901_ $$aEnvironmental Chemistry for a Sustainable World ;$$vv.71 001451386 500__ $$aIncludes index. 001451386 5050_ $$aChapter 1. The tumor microenvironment -- Chapter 2. Methods of formulation of polymeric nanoparticles -- Chapter 3. Natural polymers based nanoparticles targeted to solid tumors -- Chapter 4. Optimization of physicochemical properties of polymeric nanoparticles for targeting solid tumors -- Chapter 5. Passive and active targeting approaches for solid tumors -- Chapter 6. Polymeric nanoparticles entrapping natural drugs for cancer therapy -- Chapter 7. Polymeric nanoparticles entrapping drug combinations targeted to solid tumors -- Chapter 8. Ligands specific to over-expressed receptors in solid tumors -- Chapter 9. Ligand targeted polymeric nanoparticles for cancer chemotherapy -- Chapter 10. Polymeric nanoparticles as theranostics for targeting solid tumors -- Chapter 11. Oral delivery of polymeric nanoparticles for solid tumors -- Chapter 12. Polymeric nanoparticles to target glioblastoma tumors -- Chapter 13. Polymeric nanoparticles to target lung cancer -- Chapter 14. Polymer based nanoplatforms for targeting breast cancer -- Chapter 15. PH-Sensitive polymeric nanoparticles for cancer treatment -- Chapter 16. Polymeric nanoplatforms for targeted treatment of prostate cancer -- Chapter 17. Cellular internalization and toxicity of polymeric nanoparticles -- Chapter 18. Prospects and challenges in the treatment of solid tumors. 001451386 506__ $$aAccess limited to authorized users. 001451386 520__ $$aThis book focuses on the emerging research in the field of treatment of solid tumors or cancer with new drug delivery systems using nanotechnology. Nanotechnology has given us a good scope for development of new innovative drug delivery strategies to increase the therapeutic efficacy of anticancer drugs with reduced off-target side effects. Cancer is one of the main causes of death worldwide due to the limitations of classical therapies such as low solubility of active drugs, toxic side effects on healthy cells and resistance of tumor cells. These issues are partly solved by the recent development of polymeric nanoparticles, which improve drug absorption and the therapeutic index, while reducing side effects. Drug carriers must be biocompatible, biodegradable and non-immunogenic. Coupled to a ligand that has affinity for that particular cell, polymeric nanoparticles are used to target specifically malignant cells or tissues and, in turn, improve drug stability. This book presents the latest advances in the application of polymeric particles for cancer treatment, with focus on the tumor microenvironment, synthesis, active and passive targeting, patents, targeting over-expressed receptors, tumor-targeting ligands, theranostics, glioblastoma tumors, lung cancer, breast cancer, prostate cancer and pH-responsive nanoparticles. 001451386 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed November 29, 2022). 001451386 650_0 $$aCancer$$xTreatment$$xTechnological innovations. 001451386 650_0 $$aNanoparticles$$xTherapeutic use. 001451386 655_0 $$aElectronic books. 001451386 7001_ $$aPadhi, Santwana. 001451386 7001_ $$aBehera, Anindita. 001451386 7001_ $$aLichtfouse, Eric. 001451386 77608 $$iPrint version:$$aPadhi, Santwana$$tPolymeric Nanoparticles for the Treatment of Solid Tumors$$dCham : Springer International Publishing AG,c2022$$z9783031148477 001451386 830_0 $$aEnvironmental chemistry for a sustainable world ;$$vv. 71. 001451386 852__ $$bebk 001451386 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-031-14848-4$$zOnline Access$$91397441.1 001451386 909CO $$ooai:library.usi.edu:1451386$$pGLOBAL_SET 001451386 980__ $$aBIB 001451386 980__ $$aEBOOK 001451386 982__ $$aEbook 001451386 983__ $$aOnline 001451386 994__ $$a92$$bISE