001451673 000__ 03109cam\a2200529\i\4500
001451673 001__ 1451673
001451673 003__ OCoLC
001451673 005__ 20230310004712.0
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001451673 008__ 221206s2022\\\\sz\\\\\\o\\\\\000\0\eng\d
001451673 019__ $$a1352234303$$a1352974305
001451673 020__ $$a9783031186295$$q(electronic bk.)
001451673 020__ $$a303118629X$$q(electronic bk.)
001451673 020__ $$z9783031186288
001451673 020__ $$z3031186281
001451673 0247_ $$a10.1007/978-3-031-18629-5$$2doi
001451673 035__ $$aSP(OCoLC)1353296907
001451673 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dYDX$$dEBLCP$$dOCLCF$$dUKAHL$$dOCLCQ
001451673 049__ $$aISEA
001451673 050_4 $$aRS419
001451673 08204 $$a615.1/9$$223/eng/20221206
001451673 24500 $$aDNA-encoded libraries /$$cAndreas Brunschweiger, Damian W. Young, editors ; with contributions by M.J. Anderson [and 24 others].
001451673 264_1 $$aCham :$$bSpringer,$$c[2022]
001451673 264_4 $$c©2022
001451673 300__ $$a1 online resource (ix, 276 pages).
001451673 336__ $$atext$$btxt$$2rdacontent
001451673 337__ $$acomputer$$bc$$2rdamedia
001451673 338__ $$aonline resource$$bcr$$2rdacarrier
001451673 4901_ $$aTopics in medicinal chemistry ;$$vvolume 40
001451673 5050_ $$aA History of Selection-Based High-Throughput Screening Technologies for Hit Identification -- Barcoding Strategies for the Synthesis of Genetically Encoded Chemical Libraries -- Advancements in DEL-Compatible Chemical Reactions -- Design Considerations in Constructing and Screening DNA-Encoded Libraries -- Cheminformatics Approaches Aiding the Design and Selection of DNA-Encoded Libraries -- Selection Strategies in DNA-Encoded Libraries -- From DEL Selections to Validated Hits to Clinical Leads -- A Perspective on 30 Years of DNA-Encoded Chemistry. .
001451673 506__ $$aAccess limited to authorized users.
001451673 520__ $$aThis book deals with the recent advances in DNA-Encoded Library (DEL) technology that has emerged as an alternative to high throughput screening(HTS) over the last decade and has been heralded as a "disruptive" technology for drug discovery. The book aims to provide a comprehensive overview of all of the major components of the DEL process from conception to bench execution and clinical investigations. The contributions from experts in the field combine different perspectives from academia and industry. The book will be of interest to researchers in the drug discovery field as well as graduate students and scholars who are interested in this rapidly improving technology.
001451673 588__ $$aDescription based on print version record.
001451673 650_0 $$aCombinatorial chemistry.
001451673 650_0 $$aDNA$$xSynthesis.
001451673 655_0 $$aElectronic books.
001451673 7001_ $$aBrunschweiger, Andreas,$$eeditor.
001451673 7001_ $$aYoung, Damian W.,$$eeditor.
001451673 77608 $$iPrint version:$$tDNA-encoded libraries.$$dCham : Springer, 2022$$z9783031186288$$w(OCoLC)1346942339
001451673 830_0 $$aTopics in medicinal chemistry (Springer (Firm)) ;$$vv. 40.
001451673 852__ $$bebk
001451673 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-031-18629-5$$zOnline Access$$91397441.1
001451673 909CO $$ooai:library.usi.edu:1451673$$pGLOBAL_SET
001451673 980__ $$aBIB
001451673 980__ $$aEBOOK
001451673 982__ $$aEbook
001451673 983__ $$aOnline
001451673 994__ $$a92$$bISE