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Table of Contents
Intro
Contents
Stereotactic Radioablation for Treatment of Ventricular Tachycardia
1 Introduction
2 Mechanisms of Scar-Related Ventricular Tachycardia and Radiofrequency Catheter Ablation Treatment
3 Basic Principles of STAR and Pre-clinical Studies
4 Clinical Studies
4.1 Treatment Efficacy
4.2 Treatment Safety
5 STAR Diagnostic Workup
5.1 Cardiovascular Evaluation
5.2 Radiotherapy Planning and Delivery
6 Ongoing Trials and Registries
References
Pulsed Field Ablation for the Interventional Treatment of Cardiac Arrhythmias
1 Introduction
2 From Irreversible Electroporation to Pulsed Field Ablation
2.1 Preclinical Investigation
2.2 Clinical Investigation
3 Modeling Electroporation to Aid Clinical Therapy
4 Current Open Issues with Pulsed Field Ablation and Conclusions
References
High-Power Short-Duration Radiofrequency Ablation of Atrial Fibrillation
1 Introduction
2 RF Lesion Formation
3 HPSD Ablation Characteristic
4 HPSD Ablation Outcomes
5 Safety of HPSD Ablation
6 Limitations of HPSD Ablation
7 Conclusions
References
The Evolving Role of the Cardiac Conduction System in Cardiac Resynchronisation Therapy and Cardiac Pacing
1 Introduction
2 Conduction System Pacing for Cardiac Resynchronisation
2.1 Anatomy of the Conduction System
2.2 Implantation Procedure
2.3 Types of Capture and ECG Characteristics of CSP
2.4 CSP in LBBB
2.5 CSP in Non-LBBB
2.6 CSP in Patients with Pacing-Induced Cardiomyopathy
2.7 CSP as Prevention of Pacing-Induced Cardiomyopathy When a High Ventricular Pacing Burden is Expected
2.8 CSP Testing and Device Programming
2.9 CSP Limitations
3 Conclusions
4 Images
5 Further Types of Data
6 Outlook and Conclusion
References
Cardiac Digital Twin Modeling
1 Introduction
2 Construction of Anatomical Models
2.1 Geometrical Model Acquisition
2.2 Model Augmentation
3 Functional Twinning
3.1 Cellular Characteristics
3.2 Tissue Characteristics
4 Applications in Risk Prediction and Therapy Planning
4.1 Prediction of Ablation Targets for Atrial Fibrillation and Atrial Flutter
4.2 Prediction of Sudden Cardiac Death Risk
4.3 Optimal Electrode and Implantable Cardioverter Defibrillator Placement Evaluation
Contents
Stereotactic Radioablation for Treatment of Ventricular Tachycardia
1 Introduction
2 Mechanisms of Scar-Related Ventricular Tachycardia and Radiofrequency Catheter Ablation Treatment
3 Basic Principles of STAR and Pre-clinical Studies
4 Clinical Studies
4.1 Treatment Efficacy
4.2 Treatment Safety
5 STAR Diagnostic Workup
5.1 Cardiovascular Evaluation
5.2 Radiotherapy Planning and Delivery
6 Ongoing Trials and Registries
References
Pulsed Field Ablation for the Interventional Treatment of Cardiac Arrhythmias
1 Introduction
2 From Irreversible Electroporation to Pulsed Field Ablation
2.1 Preclinical Investigation
2.2 Clinical Investigation
3 Modeling Electroporation to Aid Clinical Therapy
4 Current Open Issues with Pulsed Field Ablation and Conclusions
References
High-Power Short-Duration Radiofrequency Ablation of Atrial Fibrillation
1 Introduction
2 RF Lesion Formation
3 HPSD Ablation Characteristic
4 HPSD Ablation Outcomes
5 Safety of HPSD Ablation
6 Limitations of HPSD Ablation
7 Conclusions
References
The Evolving Role of the Cardiac Conduction System in Cardiac Resynchronisation Therapy and Cardiac Pacing
1 Introduction
2 Conduction System Pacing for Cardiac Resynchronisation
2.1 Anatomy of the Conduction System
2.2 Implantation Procedure
2.3 Types of Capture and ECG Characteristics of CSP
2.4 CSP in LBBB
2.5 CSP in Non-LBBB
2.6 CSP in Patients with Pacing-Induced Cardiomyopathy
2.7 CSP as Prevention of Pacing-Induced Cardiomyopathy When a High Ventricular Pacing Burden is Expected
2.8 CSP Testing and Device Programming
2.9 CSP Limitations
3 Conclusions
4 Images
5 Further Types of Data
6 Outlook and Conclusion
References
Cardiac Digital Twin Modeling
1 Introduction
2 Construction of Anatomical Models
2.1 Geometrical Model Acquisition
2.2 Model Augmentation
3 Functional Twinning
3.1 Cellular Characteristics
3.2 Tissue Characteristics
4 Applications in Risk Prediction and Therapy Planning
4.1 Prediction of Ablation Targets for Atrial Fibrillation and Atrial Flutter
4.2 Prediction of Sudden Cardiac Death Risk
4.3 Optimal Electrode and Implantable Cardioverter Defibrillator Placement Evaluation