Discovery DMPK quick guide: guide to data interpretation and integration / S. Cyrus Khojasteh, Harvey Wong, Donglu Zhang, Cornelis E.C.A. Hop.
Khojasteh, Siamak Cyrus.; Wong, Harvey.; Zhang, Donglu.; Hop, Cornelis E. C. A.
2022
RM301.25
Available Online

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Title Discovery DMPK quick guide: guide to data interpretation and integration / S. Cyrus Khojasteh, Harvey Wong, Donglu Zhang, Cornelis E.C.A. Hop.
Author Khojasteh, Siamak Cyrus.
ISBN 9783031106910 (electronic bk.)
3031106911 (electronic bk.)
3031106903
9783031106903
DOI https://doi.org/10.1007/978-3-031-10691-0
Publication Details Cham : Springer, 2022.
Language English
Description 1 online resource (241 p.)
Item Number 10.1007/978-3-031-10691-0 doi
Call Number RM301.25
Dewey Decimal Classification 615.1/9
Summary This book is intended for a broad readership, in particular, those working or interested in drug discovery coming from various disciplines such as medicinal chemistry, pharmacology, drug metabolism and pharmacokinetics, bioanalysis, clinical sciences, biochemistry, pharmaceutics, and toxicology. It provides, for the first time, a completely integrated look at multiple aspects of ADME sciences (absorption, distribution, metabolism, and excretion) in a summary format that is clear, concise, and self-explanatory. DMPK in Drug Discovery - Guide to Data Interpretation and integration leverages the prior knowledge from the first book that covers the basics of each concept (Drug Metabolism and Pharmacokinetics Quick Guide). This reference book is meant to be used day to day and provides many useful tables (used for data interpretation), figures, and case studies that can facilitate drug discovery. The case studies are intended to be short and relevant to the topic discussed and present another dimension to the discussions.
Access Note Access limited to authorized users.
Source of Description Online resource; title from PDF title page (SpringerLink, viewed January 6, 2023).
Added Author Wong, Harvey.
Zhang, Donglu.
Hop, Cornelis E. C. A.
Available in Other Form Discovery DMPK Quick Guide
Linked Resources Online Access
Record Appears in Online Resources > Ebooks
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Goals for DMPK during drug optimizations
Drug Properties
DMPK in lead optimization
Candidate tranlational characterization
Q&A of DMPK issues and tools for drug discovery
ADME assays
Regulatory documents for IND to Support FIH
Appendix: Chemical nomenclature.

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