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Document Delivery Supplied
Can lend chapters, not whole ebooks
Title
The centrosome and its functions and dysfunctions / Heide Schatten.
ISBN
9783031208485 (electronic bk.)
303120848X (electronic bk.)
9783031208478
3031208471
Published
Cham, Switzerland : Springer, 2022.
Language
English
Description
1 online resource (vii, 111 pages) : illustrations (some color).
Item Number
10.1007/978-3-031-20848-5 doi
Call Number
QH597
Dewey Decimal Classification
571.6/5
Summary
The book provides a comprehensive overview of classic and modern approaches of centrosome research, including new aspects of centrosome functions focusing on primary cilia and their implications in numerous diseases. In addition, several chapters raise awareness of centrosomes in areas that have not yet fully considered the centrosome as an organelle that impacts other organelle functions directly or indirectly. It further relates centrosome functions to other research areas such as aging and stem cell research. Since its discovery almost 150 years ago the centrosome is increasingly being recognized as a most impactful organelle for its role, not only as primary microtubule organizing center (MTOC) but also as a major communication center for signal transduction pathways and as a center for proteolytic activities. Its significance for cell cycle regulation has been well studied and we now also know that centrosome dysfunctions are implicated in numerous diseases and disorders including cancer, cystic diseases of the kidney, liver fibrosis, cardiac defects, obesity and several other diseases and disorders. This new volume reviews the latest advances in the field and provides valuable background information that is readily understandable for the newcomer and the experienced centrosome researcher alike. Due to the interdisciplinary of the subject, it is a valuable resource for researchers and clinicians working in biomedical research, cell biology, cancer biology, reproduction and developmental biology, neuroscience and stem cell research.
Access Note
Access limited to authorized users.
Source of Description
Online resource; title from PDF title page (SpringerLink, viewed December 21, 2022).
Series
Advances in anatomy, embryology, and cell biology ; v. 235. 2192-7065
Available in Other Form
Print version: 9783031208478
Cell and Molecular Biology of Centrosome Structure and Function
The centrosome Cycle within the cell cycle
Centrosome as center for proteolytic activity and dysfunctions associated with pathogenesis of human disease
Centrosome dysfunctions in cancer
Virus exploitation of centrosomes
Centrosomes in reproduction
Transition from centrosomal to non-centrosomal microtubule organization during cellular polarization
External and environmental effects on Centrosomes
Centrosomes and centrosome equivalents in other systems
Non-centrosomal microtubule organization in plant cells.
