001452851 000__ 03083cam\a2200505\i\4500
001452851 001__ 1452851
001452851 003__ OCoLC
001452851 005__ 20230314003321.0
001452851 006__ m\\\\\o\\d\\\\\\\\
001452851 007__ cr\cn\nnnunnun
001452851 008__ 220822s2023\\\\si\\\\\\ob\\\\000\0\eng\d
001452851 020__ $$a9789811942747$$q(electronic bk.)
001452851 020__ $$a9811942749$$q(electronic bk.)
001452851 020__ $$z9789811942730
001452851 0247_ $$a10.1007/978-981-19-4274-7$$2doi
001452851 035__ $$aSP(OCoLC)1341675067
001452851 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dOCLCF$$dOCLCQ
001452851 049__ $$aISEA
001452851 050_4 $$aTA164
001452851 08204 $$a570.28$$223/eng/20220822
001452851 1001_ $$aChoi, Hansol,$$eauthor.
001452851 24510 $$aPurifying and indexing technology for nucleic acids-based next generation storage medium /$$cHansol Choi.
001452851 264_1 $$aSingapore :$$bSpringer,$$c[2023]
001452851 300__ $$a1 online resource (xv, 42 pages) :$$billustrations (some color).
001452851 336__ $$atext$$btxt$$2rdacontent
001452851 337__ $$acomputer$$bc$$2rdamedia
001452851 338__ $$aonline resource$$bcr$$2rdacarrier
001452851 4901_ $$aSpringer theses,$$x2190-5061
001452851 500__ $$a"Doctoral Thesis accepted by Seoul National University, Seoul, South Korea."
001452851 504__ $$aIncludes bibliographical references.
001452851 5050_ $$aIntroduction -- Synthetic Nucleic Acids Storage -- Highly Parallel Oligonucleotide Libraries Purification -- Conclusion and Discussion.
001452851 506__ $$aAccess limited to authorized users.
001452851 520__ $$aThis book introduces novel purification technology for the complex oligonucleotide libraries. Since the concept of synthesizing oligonucleotides (oligos) has been proposed, research fields such as nucleic acid-based therapies (CRISPR-Cas9, DNA/RNA vaccines, RNAi), synthetic biology, protein engineering, and DNA-based data storage have bloomed. The COVID-19 pandemic underscores the potential of nucleic acid-based technologies, such as vaccines or diagnostics. As they emerge as the most promising weapons against the current pandemic, increasing need for highly accessible nucleic acid purification technologies is expected. To meet this demand, an oligo purification technology that can be applied to complex oligo libraries and can purify oligos with single-base resolution is developed. In addition, the purification technology can be applied to highly complex oligo libraries of different lengths, enabling the simultaneous purification of complex oligo libraries with different lengths. The proposed technology can be easily accessed by users and would help accelerate numerous research fields that utilize oligos as fundamental building blocks.
001452851 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed August 22, 2022).
001452851 650_0 $$aSynthetic biology.
001452851 650_0 $$aNucleic acids$$xBiotechnology.
001452851 650_0 $$aNanobiotechnology.
001452851 655_0 $$aElectronic books.
001452851 830_0 $$aSpringer theses,$$x2190-5061
001452851 852__ $$bebk
001452851 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-981-19-4274-7$$zOnline Access$$91397441.1
001452851 909CO $$ooai:library.usi.edu:1452851$$pGLOBAL_SET
001452851 980__ $$aBIB
001452851 980__ $$aEBOOK
001452851 982__ $$aEbook
001452851 983__ $$aOnline
001452851 994__ $$a92$$bISE