TY - GEN N2 - This new edition provides comprehensive coverage of the variety and complexity of the roles that glycoconjugates play in the cells of the nervous system. Basic fundamental principles as well as the latest developments in neural glycobiology are discussed. Topics covered range from the structure and metabolism of the saccharide chains and current approaches used in their study, to changes glycoconjugates undergo during development and aging of the nervous system and the roles they have in neurological disease. New topics include a detailed discussion of cells found within the nervous system, an extensive listing of congenital disorders of glycosylation of both proteins and lipids, the roles of glycans in neuronal axon growth/guidance and voltage-gated channels, the role of intra-lysosomal luminal vesicles in lysosomal storage disorders, and, in the time of the COVID-19 pandemic, the role of carbohydrates in infection by SARS-CoV-2. The breadth and depth of topics covered make this an essential reference for those new to the field as well as for more experienced investigators. DO - 10.1007/978-3-031-12390-0 DO - doi AB - This new edition provides comprehensive coverage of the variety and complexity of the roles that glycoconjugates play in the cells of the nervous system. Basic fundamental principles as well as the latest developments in neural glycobiology are discussed. Topics covered range from the structure and metabolism of the saccharide chains and current approaches used in their study, to changes glycoconjugates undergo during development and aging of the nervous system and the roles they have in neurological disease. New topics include a detailed discussion of cells found within the nervous system, an extensive listing of congenital disorders of glycosylation of both proteins and lipids, the roles of glycans in neuronal axon growth/guidance and voltage-gated channels, the role of intra-lysosomal luminal vesicles in lysosomal storage disorders, and, in the time of the COVID-19 pandemic, the role of carbohydrates in infection by SARS-CoV-2. The breadth and depth of topics covered make this an essential reference for those new to the field as well as for more experienced investigators. T1 - Glycobiology of the nervous system / AU - Yu, Robert K., AU - Schengrund, Cara-Lynne, ET - Second edition. VL - volume 29 CN - QP702.G577 N1 - Previous edition: 2014. ID - 1453121 KW - Glycomics. KW - Nervous system KW - Glycoconjugates. KW - Neurobiology. SN - 9783031123900 SN - 3031123905 TI - Glycobiology of the nervous system / LK - https://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-031-12390-0 UR - https://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-031-12390-0 ER -