Intro
Preface
Contents
About the Author
Part I: Extracorporeal Circulation and Low Invasiveness
1: Experience of Minimally Invasive Extracorporeal Circulation
1.1 Introduction
1.2 Implications of Invasion and Minimally Invasiveness in Cardiac Surgery
1.3 Extracorporeal Circulation Method for Minimally Invasive
1.4 History of Minimally Invasive Measures at Sakakibara Heart Institute
1.4.1 Establishment and Clinical Effect of Ultrafiltration Method
1.4.1.1 ECUM Effect in Infant VSD (1990)

1.4.1.2 ECUM Effect in Complete Atrioventricular Septal Defect (AVSD) (1992-1993)
1.4.2 Problems with Ultrafiltration
1.4.2.1 Protein Leakage (1991-1992)
1.4.2.2 Arrhythmia (1991-1993)
1.4.3 Advances in Ultrafiltration Methods
1.4.3.1 Measurement of Inflammatory Reactive Substances (1991-1993)
ECUM Only After the Start of Rewarming
Ultrafiltration During Aortic Cross-Clamp + During Rewarming
1.4.3.2 Measurement of Inflammatory Reactive Substances (1994-1995)
1.4.3.3 New Heart-Lung Machine and Inflammatory Reactive Substances (1997-1998)

1.5 Summary of Minimally Invasive
References
2: Development of Cardiopulmonary Bypass System and Devices Aiming for Minimally Invasive
2.1 Introduction
2.2 Development History
2.2.1 Low-Volume Oxygenator 1
2.2.2 Component Type Heart-Lung Machine
2.2.3 Low-Volume Oxygenator 2
2.2.4 Low-Volume Oxygenator 3
2.2.5 Isolated Pump-Controller Heart-Lung Machine 1
2.2.6 Low-Volume Oxygenator 4
2.2.7 Isolated Pump-Controller Heart-Lung Machine 2
2.2.8 Isolated Pump-Controller Heart-Lung Machine 3
2.2.9 The New Sakakibara Heart Institute

2.2.10 Transition of Priming Volume Reduction, Vacuum-Assisted Venous Drainage (VAVD)
2.2.11 Isolated Pump-Controller Heart-Lung Machine 4
2.2.12 Change in Priming Volume New Device
2.2.13 Current Priming Volume
2.3 Summary of Extracorporeal Circulation Devices
References
3: Advances in Bloodless Open-Heart Surgery
3.1 Introduction
3.2 Bloodless Open-Heart Surgery and Homologous Blood Transfusion
3.3 Bloodless Open-Heart Surgery for Acyanotic Congenital Heart Disease with Pulmonary Hypertension
3.3.1 1983-1992
3.3.2 1993
3.3.3 1994

3.3.4 Possibility of Bloodless Open-Heart Surgery for VSD Infant Weighing 4 kg (1995)
3.3.5 Bloodless Open-Heart Surgery in VSD Infants Weighing 3-4 kg (1997)
3.3.6 Bloodless Open-Heart Surgery for Complete AVSD: Comparison with VSD
3.3.7 Number of Blood Transfusions Used in Blood Priming Cases
3.4 Management and Measures for Bloodless Open-Heart Surgery in Low-Weight Infant
3.4.1 Determination of Indication for Bloodless Open-Heart Surgery
3.4.1.1 Indication Decision by Clinical Evaluation
3.4.1.2 Indication Decision by Hemodilution
3.4.2 Surgery
3.4.3 Anesthesia Management