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Intro
Preface
Contents
Part I: Materials for Cancer Nanotechnology
Lipid Nanocarriers for Breast Cancer Treatment
1 Introduction
2 Properties and Advantages of Lipid Nanocarriers for Breast Cancer Management
3 Lipid-Based Nanocarriers for Breast Cancer: Approved and Under Development
4 Nanocarriers for Parenteral Administration
4.1 Liposomes
4.1.1 Co-encapsulation of Drugs
4.1.2 Long-Circulating Liposomes
4.1.3 Stimulus-Responsive Liposomes
4.1.4 Ligand-Targeted Liposome
4.1.5 Liposome-Based Gene Therapy
4.1.6 Liposomes for Theranostics

4.2 Solid Lipid Nanoparticles and Nanostructured Lipid Carriers
4.3 Nanoemulsions and Microemulsions
4.4 Liquid Crystalline Phases
5 Nanocarriers for Oral Administration
5.1 Liposomes
5.2 Solid Lipid Nanoparticles (SLN) and Nanostructured Lipid Carriers (NLC)
5.3 Micro- and Nanoemulsions
5.4 Liquid Crystalline Nanoparticles (LCNPs)
6 Nanocarriers for Localized Treatment
6.1 Intraductal Therapy
6.1.1 Liposomes
6.1.2 Nanoemulsions
6.2 Topical-Transdermal Therapy
6.2.1 Vesicles
6.2.2 Micro- and Nanoemulsions
6.2.3 Lipid Nanoparticles

6.2.4 Liquid Crystalline Nanoparticles
6.3 Subcutaneous Delivery
6.3.1 Microemulsions
6.3.2 Solid Lipid Nanoparticles
7 Conclusions
References
Polymeric Nanocarriers in Cancer Theranostics
1 Introduction
2 Nanostructured Carriers and Cancer Treatment
3 Photodynamic (PDT) and Photothermal (PTT) Cancer Therapies
3.1 Photodynamic Therapy (PDT)
3.2 Photothermal Therapy (PTT)
4 Imaging Agents and Techniques in Cancer Theranostics
5 Fluorophores as Photosensitizers in Theranostics
6 Polymeric Nanoparticles as Nanotheranostics

7 Inorganic-Based Probes in Polymeric Nanoparticles for Imaging
8 Polymeric Nanoparticles with Organic Fluorescent Tracers and Photosensitizers
9 Concluding Remarks
References
Functionalization of Nanosystems in Cancer Treatment
1 Introduction
2 Strategies for Functionalization of Nanostructures
2.1 Non-covalent Functionalization
2.2 Covalent Functionalization
2.2.1 Carbodiimide Chemistry
2.2.2 Maleimide Chemistry
2.2.3 Click Chemistry
3 Active Targeting Strategies
3.1 Proteins
3.2 Peptides
3.3 Small Molecules
4 Conclusion and Future Perspectives

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