001453703 000__ 04304cam\a2200529\i\4500 001453703 001__ 1453703 001453703 003__ OCoLC 001453703 005__ 20230314003440.0 001453703 006__ m\\\\\o\\d\\\\\\\\ 001453703 007__ cr\cn\nnnunnun 001453703 008__ 230112s2023\\\\sz\a\\\\o\\\\\000\0\eng\d 001453703 019__ $$a1356796598 001453703 020__ $$a9783031230585$$q(electronic bk.) 001453703 020__ $$a3031230582$$q(electronic bk.) 001453703 020__ $$z9783031230578 001453703 020__ $$z3031230574 001453703 0247_ $$a10.1007/978-3-031-23058-5$$2doi 001453703 035__ $$aSP(OCoLC)1356794942 001453703 040__ $$aYDX$$beng$$erda$$epn$$cYDX$$dGW5XE$$dUKAHL 001453703 049__ $$aISEA 001453703 050_4 $$aRM315 001453703 08204 $$a615.7/8$$223/eng/20230112 001453703 24500 $$aTherapeutic applications of dopamine D3 receptor function :$$bnew insight after 30 years of research /$$cIsabelle Boileau, Ginetta Collo, editors. 001453703 264_1 $$aCham :$$bSpringer,$$c[2023] 001453703 264_4 $$c©2023 001453703 300__ $$a1 online resource (viii, 275 pages) :$$billustrations. 001453703 336__ $$atext$$btxt$$2rdacontent 001453703 337__ $$acomputer$$bc$$2rdamedia 001453703 338__ $$aonline resource$$bcr$$2rdacarrier 001453703 4901_ $$aCurrent topics in behavioral neurosciences,$$x1866-3389 ;$$vvolume 60 001453703 5050_ $$aPreface -- A Historic Review of the D3 Dopamine System from D3 Cloning to Clinical Trials in Schizophrenia and Drug Addiction -- Location, Location, Location: The Expression of D3 Dopamine Receptors in the Nervous System -- Recent Advances in Dopamine D3 Receptor Heterodimers: Focus on Dopamine D3 and D1 Receptor-Receptor Interaction and Striatal Function -- Involvement of DA D3 Receptor and Mitochondrial Functions in Structural Neuroplasticity of the Emotional Brain Circuits: Possible Role in Depression -- Dopamine D3 Receptor in Parkinson Disease: A Prognosis Biomarker and an Intervention Target -- Dopamine D3 Receptors: A Potential Target to Treat Motivational Deficits in Parkinsons Disease -- Therapeutic Challenges of Cognitive Dysfunctions in Neuropsychiatric Disorders: Focus on the Dopamine D3 Receptor -- Dopamine D3 Receptor in Stimulant and Opiate Use Disorders -- The Role of D3 Dopamine-Receptors in Nicotine Dependence: A Synthesis of the Pre-Clinical and Clinical Literature -- The Dopamine D3 receptor in Food Addiction -- The Dopamine D3 Receptor Pharmacology and the Therapeutic Use of D3 Receptor Ligands in Schizophrenia -- D3 receptors and Restless Legs Syndrome -- D3 receptors and PET imaging. 001453703 506__ $$aAccess limited to authorized users. 001453703 520__ $$aThe CTBN volume Therapeutic Applications of Dopamine D3 Receptor Function reviews the state of the knowledge on the dopamine D3 receptor and its role in human behavior and disease (i.e.: neuropsychiatric illnesses including schizophrenia, mood disorders, Parkinsons disease, restless legs syndrome, addictions and substance use disorders). The volume is written by leading experts across multidisciplinary areas (imaging, biobehavioral testing and clinical trials, preclinical models / molecular pharmacology) converging on the therapeutic implications / potential of the D3 receptor. The D3 dopamine receptor is a member of the D2-like family of G protein-coupled receptors. It was cloned and characterized almost 25 years ago. A key feature of the D3 dopamine receptor system, which has attracted considerable attention, is its anatomical localization remarkably restricted to the limbic circuitry. This has spurred the hypothesis that D3 involvement could contribute to the pathophysiology of neuropsychiatric disorders (or to some features of neuropsychiatric disorders), including but not limited to psychosis, addictions and substance abuse, mood and movement disorders. 001453703 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed January 12, 2023). 001453703 650_0 $$aPsychopharmacology. 001453703 650_0 $$aDopamine$$xReceptors. 001453703 655_0 $$aElectronic books. 001453703 7001_ $$aBoileau, Isabelle,$$eeditor. 001453703 7001_ $$aCollo, Ginetta,$$eeditor. 001453703 77608 $$iPrint version: $$z3031230574$$z9783031230578$$w(OCoLC)1351464296 001453703 830_0 $$aCurrent topics in behavioral neurosciences ;$$v60.$$x1866-3389 001453703 852__ $$bebk 001453703 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-031-23058-5$$zOnline Access$$91397441.1 001453703 909CO $$ooai:library.usi.edu:1453703$$pGLOBAL_SET 001453703 980__ $$aBIB 001453703 980__ $$aEBOOK 001453703 982__ $$aEbook 001453703 983__ $$aOnline 001453703 994__ $$a92$$bISE