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Bioinformatics for evolutionary biologists : a problems approach / Bernhard Haubold, Angelika Börsch-Haubold.

Haubold, Bernhard, 1967- author.; Börsch-Haubold, Angelika, author.
2023
QH324.2
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Title
Bioinformatics for evolutionary biologists : a problems approach / Bernhard Haubold, Angelika Börsch-Haubold.
Author
Haubold, Bernhard, 1967- author.
Edition
Second edition.
ISBN
9783031204142 (electronic bk.)
303120414X (electronic bk.)
9783031204135
3031204131
DOI
https://doi.org/10.1007/978-3-031-20414-2
Published
Cham : Springer, [2023]
Copyright
©2023
Language
English
Description
1 online resource (ix, 411 pages) : illustrations (some color)
Item Number
10.1007/978-3-031-20414-2 doi
Call Number
QH324.2
Dewey Decimal Classification
570.285
Summary
This self-contained textbook covers fundamental aspects of sequence analysis with special emphasis on evolutionary biology, including sequence alignment, exact matching, phylogeny reconstruction, and coalescent simulation. It addresses these topics through a series of over 800 computer problems, ranging from elementary to research level, to enable learning by doing. Students solve the problems in the same computational environment used for decades in science the Unix command line. This is available on all four major operating systems for PCs: Windows, macOS, chromeOS, and Linux. To learn using this powerful system, students analyze sample sequence data by applying generic tools, bioinformatics software, and over 50 programs specifically written for this course and available via GitHub. The solutions for all problems are included, making the book ideal for self-study. Problems are grouped into sections headed by an introduction and a list of new terms. By using practical computing to explore sequence data in an evolutionary context, the book enables readers to tackle their own computational problems.
Bibliography, etc. Note
Includes bibliographical references and index.
Access Note
Access limited to authorized users.
Source of Description
Description based on print version record.
Added Author
Börsch-Haubold, Angelika, author.
Available in Other Form
Bioinformatics for evolutionary biologists.
Linked Resources
Online Access
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Part I Problems
1 The Unix Command Line
1.1 Getting Started
1.2 Files, Directories, and Programs.-1.3 Scripts
2 Optimal Alignment
2.1 Keeping Score
2.2 Construction
2.3 Application
3 Exact Matching
3.1 Keyword Trees
3.2 Suffix Trees
3.3 Suffix Arrays
3.4 Text Compression
4 Fast Alignment
4.1 Global
4.2 Local
4.3 Glocal
4.4 Assembly
4.5 Multiple Sequences
5 Evolution Between Species: Phylogeny
5.1 Trees of Life
5.2 Rooted Trees
5.3 Unrooted Trees
6 Evolution within Populations
6.1 Descent from One or Two Parents
6.2 The Coalescent
7 Interrogating and Storing Data
7.1 Statistics
7.2 Relational Databases
Part II Answers.
1 The Unix Command Line
1.1 Getting Started
1.2 Files, Directories, and Programs
1.3 Scripts
2 Optimal Alignment
2.1 Keeping Score
2.2 Construction
2.3 Application
3 Exact Matching
3.1 Keyword Trees
3.2 Suffix Trees
3.3 Suffix Arrays
3.4 Text Compression
4 Fast Alignment
4.1 Global
4.2 Local
4.3 Glocal
4.4 Assembly
4.5 Multiple Sequences
5 Evolution Between Species: Phylogeny
5.1 Trees of Life
5.2 Rooted Trees
5.3 Unrooted Trees
6 Evolution within Populations
6.1 Descent from One or Two Parents
6.2 The Coalescent
7 Interrogating and Storing Data
7.1 Statistics
7.2 Relational Databases
A. Unix Guide
B. Programs
B.1 Own
B.2 Biobox
B.3 Third-Party
References
Index.

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