Protein-based therapeutics / Dev Bukhsh Singh, Timir Tripathi, editors.
Singh, Dev Bukhsh, editor.; Tripathi, Timir, editor.
2023
RS431.P75 P76 2023
Available Online

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Title Protein-based therapeutics / Dev Bukhsh Singh, Timir Tripathi, editors.
ISBN 9789811982491 (electronic bk.)
981198249X (electronic bk.)
9811982481
9789811982484
DOI https://doi.org/10.1007/978-981-19-8249-1
Published Singapore : Springer, [2023]
Language English
Description 1 online resource
Other Standard Identifiers 10.1007/978-981-19-8249-1 doi
Call Number RS431.P75 P76 2023
Dewey Decimal Classification 615.3
Summary This book provides an overview of the essential characteristics and clinical applications of therapeutic proteins against human diseases, including cancers, immune disorders, infections, and other diseases. It presents the latest advancements in protein engineering techniques for producing desirable therapeutic proteins. The book also covers the strategies used to formulate and deliver systemic therapeutic proteins, approved protein therapeutics and their targets, and pharmacogenetic biomarkers. Further, it discusses challenges associated with the clinical implications of therapeutic proteins, including safety, immunogenicity, protein stability, degradation, and efficacy. It illustrates the development of biosimilar antibodies, optimization strategies for producing biobetter antibodies, and presents fundamental concepts about biosuperior therapeutics. Lastly, it includes a discussion about protein-based vaccines against bacterial and viral infections.
Access Note Access limited to authorized users.
Source of Description Online resource; title from PDF title page (SpringerLink, viewed March 16, 2023).
Added Author Singh, Dev Bukhsh, editor.
Tripathi, Timir, editor.
Available in Other Form Print version: 9789811982484
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Chapter 1_Introduction to Protein Therapeutics.
Chapter 2_Clinical Applications of Protein-based Therapeutics Against Various Diseases.
Chapter 3_Protein Engineering Methods for the Design of Protein Therapeutics
Chapter 4_Recombinant Production of Therapeutic Proteins
Chapter 5_Antibodies as Protein Therapeutics
Chapter 6_Streptokinase: The Success Story of a Therapeutic Protein
Chapter 7_Strategies for Formulation and Systemic Delivery of Therapeutic Proteins
Chapter 8_Approved Protein Therapeutics and Their Biochemical Targets
Chapter 9_Pharmacogenetic Biomarkers of Protein Therapeutics
Chapter 10_Immunogenicity of Therapeutic Proteins
Chapter 11_Efficacy and Safety Issues of Therapeutic Proteins
Chapter 12_Emerging Trends, Challenges, and Opportunities in Protein Therapeutics
Chapter 13_Biosimilar, Biobetter & Biosuperior Therapeutic Proteins
Chapter 14_Therapeutic Protein-based Vaccines.

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