001461154 000__ 04070cam\a22005897i\4500 001461154 001__ 1461154 001461154 003__ OCoLC 001461154 005__ 20230502014307.0 001461154 006__ m\\\\\o\\d\\\\\\\\ 001461154 007__ cr\cn\nnnunnun 001461154 008__ 230307s2023\\\\si\\\\\\o\\\\\000\0\eng\d 001461154 019__ $$a1372399025 001461154 020__ $$a9789811982491$$q(electronic bk.) 001461154 020__ $$a981198249X$$q(electronic bk.) 001461154 020__ $$z9811982481 001461154 020__ $$z9789811982484 001461154 0247_ $$a10.1007/978-981-19-8249-1$$2doi 001461154 035__ $$aSP(OCoLC)1371483969 001461154 040__ $$aYDX$$beng$$erda$$cYDX$$dGW5XE$$dEBLCP$$dYDX$$dUKAHL$$dOCLCF 001461154 049__ $$aISEA 001461154 050_4 $$aRS431.P75$$bP76 2023 001461154 08204 $$a615.3$$223/eng/20230316 001461154 24500 $$aProtein-based therapeutics /$$cDev Bukhsh Singh, Timir Tripathi, editors. 001461154 264_1 $$aSingapore :$$bSpringer,$$c[2023] 001461154 300__ $$a1 online resource 001461154 336__ $$atext$$btxt$$2rdacontent 001461154 337__ $$acomputer$$bc$$2rdamedia 001461154 338__ $$aonline resource$$bcr$$2rdacarrier 001461154 5050_ $$aChapter 1_Introduction to Protein Therapeutics. -- Chapter 2_Clinical Applications of Protein-based Therapeutics Against Various Diseases. -- Chapter 3_Protein Engineering Methods for the Design of Protein Therapeutics -- Chapter 4_Recombinant Production of Therapeutic Proteins -- Chapter 5_Antibodies as Protein Therapeutics -- Chapter 6_Streptokinase: The Success Story of a Therapeutic Protein -- Chapter 7_Strategies for Formulation and Systemic Delivery of Therapeutic Proteins -- Chapter 8_Approved Protein Therapeutics and Their Biochemical Targets -- Chapter 9_Pharmacogenetic Biomarkers of Protein Therapeutics -- Chapter 10_Immunogenicity of Therapeutic Proteins -- Chapter 11_Efficacy and Safety Issues of Therapeutic Proteins -- Chapter 12_Emerging Trends, Challenges, and Opportunities in Protein Therapeutics -- Chapter 13_Biosimilar, Biobetter & Biosuperior Therapeutic Proteins -- Chapter 14_Therapeutic Protein-based Vaccines. 001461154 506__ $$aAccess limited to authorized users. 001461154 520__ $$aThis book provides an overview of the essential characteristics and clinical applications of therapeutic proteins against human diseases, including cancers, immune disorders, infections, and other diseases. It presents the latest advancements in protein engineering techniques for producing desirable therapeutic proteins. The book also covers the strategies used to formulate and deliver systemic therapeutic proteins, approved protein therapeutics and their targets, and pharmacogenetic biomarkers. Further, it discusses challenges associated with the clinical implications of therapeutic proteins, including safety, immunogenicity, protein stability, degradation, and efficacy. It illustrates the development of biosimilar antibodies, optimization strategies for producing biobetter antibodies, and presents fundamental concepts about biosuperior therapeutics. Lastly, it includes a discussion about protein-based vaccines against bacterial and viral infections. 001461154 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed March 16, 2023). 001461154 650_0 $$aProteins$$xTherapeutic use. 001461154 650_0 $$aProtein drugs. 001461154 655_0 $$aElectronic books. 001461154 7001_ $$aSingh, Dev Bukhsh,$$eeditor. 001461154 7001_ $$aTripathi, Timir,$$eeditor. 001461154 77608 $$iPrint version: $$z9811982481$$z9789811982484$$w(OCoLC)1348380441 001461154 852__ $$bebk 001461154 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-981-19-8249-1$$zOnline Access$$91397441.1 001461154 909CO $$ooai:library.usi.edu:1461154$$pGLOBAL_SET 001461154 980__ $$aBIB 001461154 980__ $$aEBOOK 001461154 982__ $$aEbook 001461154 983__ $$aOnline 001461154 994__ $$a92$$bISE