001461385 000__ 04334cam\a2200649\i\4500 001461385 001__ 1461385 001461385 003__ OCoLC 001461385 005__ 20230503003350.0 001461385 006__ m\\\\\o\\d\\\\\\\\ 001461385 007__ cr\cn\nnnunnun 001461385 008__ 230314s2023\\\\sz\a\\\\ob\\\\000\0\eng\d 001461385 019__ $$a1373338333 001461385 020__ $$a9783031175725$$q(electronic bk.) 001461385 020__ $$a3031175727$$q(electronic bk.) 001461385 020__ $$z3031175719 001461385 020__ $$z9783031175718 001461385 0247_ $$a10.1007/978-3-031-17572-5$$2doi 001461385 035__ $$aSP(OCoLC)1372557455 001461385 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dEBLCP$$dYDX$$dUKAHL 001461385 049__ $$aISEA 001461385 050_4 $$aQR186 001461385 08204 $$a616.07/9$$223/eng/20230314 001461385 24500 $$aManagement of dysregulated immune response in the critically ill /$$cZsolt Molnar, Marlies Ostermann, Manu Shankar-Hari, editors. 001461385 264_1 $$aCham :$$bSpringer,$$c[2023] 001461385 264_4 $$c©2023 001461385 300__ $$a1 online resource (xxiii, 311) :$$billustrations (chiefly color). 001461385 336__ $$atext$$btxt$$2rdacontent 001461385 337__ $$acomputer$$bc$$2rdamedia 001461385 338__ $$aonline resource$$bcr$$2rdacarrier 001461385 4901_ $$aLessons from the ICU 001461385 504__ $$aIncludes bibliographical references. 001461385 5050_ $$aForeword -- Preface -- Part I. The Host Immune Response -- Phenotypes -- The Dysregulated Host Response -- What is Cytokine Storm? -- Hemophagocytic Lymphohistiocytosis -- Extracorporeal Circulation Related Immune response -- Vasoplegic Shock -- Part II. Assessing Dysregulated Immune Response at the Bedside -- Pro- and anti-inflammatory biomarkers -- How to interpret procalcitonin? -- Assessment of the macro-, and microcirculation -- Part III. Dysregulated Immune Response and organ dysfunction -- Heart and circulation -- Brain -- Kidneys -- Liver -- Hemostasis -- The muscles -- Part IV. Modulating the immune response -- The Role of Steroids -- Why did Anti-Cytokine Therapies Fail in the Past? -- Extracorporeal cytokine removal. 001461385 506__ $$aAccess limited to authorized users. 001461385 520__ $$aThis book, part of the European Society of Intensive Care Medicine (ESICM) textbook series, deals with dysregulated host response a relatively new term introduced by the Sepsis-3 definitions in 2016. In contrast to systemic inflammatory response syndrome (SIRS) that has been used for nearly 30 years, this is a fundamentally new concept, which requires some sort of a paradigm shift in the way of thinking of critical care physicians. This change obviously requires time and after 5 years, time is ripe to summarize the knowledge in the form of a comprehensive book. The book is split in 4 sections. In the first one, the host immune response is explained in 11 chapters, followed by the next part, summarizing the possible tools for assessment at the bedside. The third and the fourth parts focus on the effects of dysregulated immune response on vital organ function and on the possible ways of immunomodulation. Written by internationally acclaimed experts of the field, the book is of value for all those intensivists and allied professionals working in ICUs. 001461385 588__ $$aDescription based on print version record. 001461385 650_0 $$aImmune response$$xRegulation. 001461385 650_0 $$aCritical care medicine. 001461385 655_0 $$aElectronic books. 001461385 7001_ $$aMolnar, Zsolt,$$eeditor. 001461385 7001_ $$aOstermann, Marlies,$$eeditor. 001461385 7001_ $$aShankar-Hari, Manu,$$eeditor. 001461385 77608 $$iPrint version:$$tMANAGEMENT OF DYSREGULATED IMMUNE RESPONSE IN THE CRITICALLY ILL.$$d[Place of publication not identified] : SPRINGER INTERNATIONAL PU, 2023$$z3031175719$$w(OCoLC)1342623072 001461385 830_0 $$aLessons from the ICU. 001461385 852__ $$bebk 001461385 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-031-17572-5$$zOnline Access$$91397441.1 001461385 909CO $$ooai:library.usi.edu:1461385$$pGLOBAL_SET 001461385 980__ $$aBIB 001461385 980__ $$aEBOOK 001461385 982__ $$aEbook 001461385 983__ $$aOnline 001461385 994__ $$a92$$bISE