@article{1461518,
      recid = {1461518},
      author = {Mir, Manzoor Ahmad,},
      title = {Therapeutic potential of cell cycle kinases in breast  cancer /},
      pages = {1 online resource (489 pages) :},
      abstract = {This book highlights the interrelation between cell cycle  regulators and breast cancer phenotypes. It reviews the  roles of Cyclin-Dependent Kinases (CDK) in driving cell  cycle progression, cell cycle checkpoints and dysregulation  in breast cancer. It also examines the prognostic  significance of CDKs in breast cancer. and CDK inhibitors  for the treatment of metastatic breast cancer. Further, the  book discusses the role of different G1 cyclins in  differentiation, chromosome stability, and transcriptional  regulation in breast cancer. Additionally, it examines the  role of immunogenic effects of CDK inhibitors, the  mechanism of resistance and the current clinical trials in  breast cancer treatment. Towards the end, the book explores  cell cycle regulation as an attractive target for targeted  drug therapy in breast cancer. This book is a comprehensive  yet concise resource for oncologists and researchers  interested in exploring the therapeutic potential of  Cyclin-Dependent Kinases in breast cancer.},
      url = {http://library.usi.edu/record/1461518},
      doi = {https://doi.org/10.1007/978-981-19-8911-7},
}