001461518 000__ 04438cam\a22005897i\4500 001461518 001__ 1461518 001461518 003__ OCoLC 001461518 005__ 20230503003357.0 001461518 006__ m\\\\\o\\d\\\\\\\\ 001461518 007__ cr\cn\nnnunnun 001461518 008__ 230317s2023\\\\si\a\\\\o\\\\\000\0\eng\d 001461518 019__ $$a1372015689$$a1372397523 001461518 020__ $$a9789811989117$$q(electronic bk.) 001461518 020__ $$a9811989117$$q(electronic bk.) 001461518 020__ $$z9811989109 001461518 020__ $$z9789811989100 001461518 0247_ $$a10.1007/978-981-19-8911-7$$2doi 001461518 035__ $$aSP(OCoLC)1373262566 001461518 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dEBLCP$$dYDX$$dUKAHL$$dOCLCF 001461518 049__ $$aISEA 001461518 050_4 $$aRC280.B8 001461518 08204 $$a616.99/449$$223/eng/20230317 001461518 24500 $$aTherapeutic potential of cell cycle kinases in breast cancer /$$cManzoor Ahmad Mir, editor. 001461518 264_1 $$aSingapore :$$bSpringer,$$c2023. 001461518 300__ $$a1 online resource (489 pages) :$$billustrations (black and white, and colour). 001461518 336__ $$atext$$btxt$$2rdacontent 001461518 337__ $$acomputer$$bc$$2rdamedia 001461518 338__ $$aonline resource$$bcr$$2rdacarrier 001461518 5050_ $$aChapter 1 An introduction to breast cancer -- Chapter 2 Current treatment approaches to breast cancer. Chapter 3 Introduction to cell cycle and its regulators -- Chapter 4 Cell cycle and cancer -- Chapter 5 cell cycle dysregulation in breast cancer -- Chapter 6 Molecular Subtypes of breast cancer and CDK dysregulation -- Chapter 7 Breast tumor micro environment and CDks -- Chapter 8 CDK Dysregulation in Breast Cancer: A Bioinformatics Analysis -- Chapter 9 CDK1 Dysregulation in Breast Cancer -- Chapter 10 CDK4/CDK6 dysregulation in estrogen positive receptor breast cancers -- Chapter 11 Therapeutic implications of CDKs in Breast Cancer -- Chapter 12 Novel CDK Inhibitors in Breast Cancer -- Chapter 13 Targeting CDKs with other chemotherapeutic drugs- A combinatorial approach -- Chapter 14 CDKs in cell-cycle progression and therapeutic strategies in Human breast cancer -- Chapter 15 CDk inhibitor for treatment of breast cancer -- Chapter 16 Response of therapy in cell cycle regulatory genes in breast cancer -- Chapter 17 Different cyclins and their significance in Breast cancer. 001461518 506__ $$aAccess limited to authorized users. 001461518 520__ $$aThis book highlights the interrelation between cell cycle regulators and breast cancer phenotypes. It reviews the roles of Cyclin-Dependent Kinases (CDK) in driving cell cycle progression, cell cycle checkpoints and dysregulation in breast cancer. It also examines the prognostic significance of CDKs in breast cancer. and CDK inhibitors for the treatment of metastatic breast cancer. Further, the book discusses the role of different G1 cyclins in differentiation, chromosome stability, and transcriptional regulation in breast cancer. Additionally, it examines the role of immunogenic effects of CDK inhibitors, the mechanism of resistance and the current clinical trials in breast cancer treatment. Towards the end, the book explores cell cycle regulation as an attractive target for targeted drug therapy in breast cancer. This book is a comprehensive yet concise resource for oncologists and researchers interested in exploring the therapeutic potential of Cyclin-Dependent Kinases in breast cancer. 001461518 588__ $$aDescription based on print version record. 001461518 650_0 $$aBreast$$xCancer$$xTreatment. 001461518 650_0 $$aCyclin-dependent kinases$$xTherapeutic use. 001461518 650_0 $$aCell cycle. 001461518 655_0 $$aElectronic books. 001461518 7001_ $$aMir, Manzoor Ahmad,$$eeditor. 001461518 77608 $$iPrint version:$$tTHERAPEUTIC POTENTIAL OF CELL CYCLE KINASES IN BREAST CANCER.$$d[Place of publication not identified] : SPRINGER VERLAG, SINGAPOR, 2023$$z9811989109$$w(OCoLC)1351462780 001461518 852__ $$bebk 001461518 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-981-19-8911-7$$zOnline Access$$91397441.1 001461518 909CO $$ooai:library.usi.edu:1461518$$pGLOBAL_SET 001461518 980__ $$aBIB 001461518 980__ $$aEBOOK 001461518 982__ $$aEbook 001461518 983__ $$aOnline 001461518 994__ $$a92$$bISE