001461558 000__ 06536cam\a22006497a\4500 001461558 001__ 1461558 001461558 003__ OCoLC 001461558 005__ 20230503003359.0 001461558 006__ m\\\\\o\\d\\\\\\\\ 001461558 007__ cr\un\nnnunnun 001461558 008__ 230318s2023\\\\si\\\\\\o\\\\\000\0\eng\d 001461558 019__ $$a1373232022 001461558 020__ $$a9789811983429$$q(electronic bk.) 001461558 020__ $$a9811983429$$q(electronic bk.) 001461558 020__ $$z9811983410 001461558 020__ $$z9789811983412 001461558 0247_ $$a10.1007/978-981-19-8342-9$$2doi 001461558 035__ $$aSP(OCoLC)1373346754 001461558 040__ $$aEBLCP$$beng$$cEBLCP$$dGW5XE$$dEBLCP$$dYDX$$dUKAHL$$dOCLCF 001461558 049__ $$aISEA 001461558 050_4 $$aRB131 001461558 08204 $$a616/.0473$$223/eng/20230324 001461558 24500 $$aBiotechnology applied to inflammatory diseases :$$bcellular mechanisms and nanomedicine /$$cDaniele Ribeiro de Araujo, Marcela Sorelli Carneiro-Ramos, editors. 001461558 260__ $$aSingapore :$$bSpringer,$$c2023. 001461558 300__ $$a1 online resource (345 p.). 001461558 4901_ $$aInterdisciplinary biotechnological advances 001461558 500__ $$a6.1.4 Glucose Phosphorylation at Mitochondria in Mammalian Cells by Hexokinase. A Signal to Survive and Control of Apoptosis. ... 001461558 5058_ $$a5.1.2.4 Challenges and Concerns in Therapeutic Nucleic Acids/Gene Therapy -- 5.2 Conclusion and Prospects -- References -- Chapter 6: Coupling Glucose Phosphorylation to Oxygen in Brain Mitochondria: Would It Be a Redox Set Point-- 6.1 Introduction -- 6.1.1 Glucose and Oxygen Fluxes in Brain, ROS and Dependence to Mitochondrial [delta]p -- 6.1.2 Controlling the Flow Mixture of Glucose and Oxygen in Brain. Do Mitochondria Play a Role-- 6.1.3 Glucose Phosphorylation at Mitochondria in Mammalian Cells by Hexokinase. Or Why Otto Meyerhof Failed to Activate Glucos... 001461558 5050_ $$aIntro -- Preface -- Contents -- About the Editors -- Chapter 1: Cardioimmunology: An Interdisciplinary Approach -- 1.1 The Heart -- 1.2 Immune System and Cardiovascular Diseases -- 1.2.1 Inflammation and Heart -- 1.2.1.1 Innate Response -- 1.2.1.2 Adaptive Response -- 1.2.1.3 Adaptative-Innate Immune Response Crosstalk and Heart -- 1.3 Biotechnological Tools Applied to the Treatment of Cardiovascular Diseases: New Insights -- 1.4 Final Considerations -- References -- Chapter 2: Vascular Inflammation: From Cellular Mechanisms to Biotechnology Advances -- 2.1 Introduction 001461558 5058_ $$a2.2 Blood Vessels and Vascular Inflammation -- 2.3 Cellular Markers of Vascular Inflammation -- 2.4 Chemical Markers of Vascular Inflammation -- 2.5 Molecular Markers of Vascular Inflammation -- 2.6 Biotechnology Advances in Diagnosis and Therapies for Vascular Inflammation -- 2.7 Conclusion and Prospects -- References -- Chapter 3: Methods for the Analysis of Arachidonic Acid-Derived Metabolites in Platelets -- 3.1 Introduction -- 3.2 AA Metabolism in Platelets: COX and LOX -- 3.3 Analytical Techniques to Detect and Quantify Bioactive Lipids in Platelets -- 3.3.1 HPLC with Ultraviolet Detection 001461558 5058_ $$a3.3.2 HPLC with Fluorimetric Detection -- 3.3.3 MS Analysis of AA-Derived Metabolites -- 3.4 Analysis of Arachidonic Acid-Derived Metabolites on Platelet Mitochondria -- 3.5 Concluding Remarks -- References -- Chapter 4: Cancer Therapy-Induced Inflammation and Its Consequences -- 4.1 How Cancer Therapy Induces Inflammation? -- 4.1.1 The Role of Cell Death -- 4.1.2 How Cell Death Signals in Inflammation and Immunity? -- 4.1.3 Cytokines, Driving Mediators of Dying Cell-Induced Inflammatory Response -- 4.2 Beyond Cytokines. The Role of Lipid Mediators Produced by Cancer Therapy 001461558 5058_ $$a4.2.1 Prostaglandin E2 (PGE2) -- 4.2.2 Platelet Activating Factor (PAF) -- 4.2.3 Resolvins -- 4.3 Modulating Inflammation for Cancer Therapy by Nanobiotechnology -- 4.4 Conclusion and Prospects -- References -- Chapter 5: Advanced Therapies for Patients with COVID-19 -- 5.1 Introduction -- 5.1.1 Mesenchymal Stromal Cell Therapy for COVID-19 -- 5.1.1.1 Use of MSCs to Treat Other Viral Infections -- 5.1.1.2 Rationale for Use of MSCs in COVID-19 -- 5.1.2 Therapeutic Nucleic Acids/Gene Therapy -- 5.1.2.1 CRISPR-Cas System -- 5.1.2.2 Antisense Oligonucleotides -- 5.1.2.3 mRNA-Based Vaccines 001461558 506__ $$aAccess limited to authorized users. 001461558 520__ $$aBiotechnology involves an interdisciplinary science that provides an interface between biological, molecular and cellular aspects of living organisms with broad technologies applicable in the fields of health, environment and materials. This book Biotechnology applied to inflammatory diseases: Cellular mechanisms and nanomedicine is focused on elaborating especially on two trendy areas from Biotechnology. In this volume, different inflammatory pathologies in terms of cellular and molecular mechanisms are characterized to better understand the science behind current precision medicine. The second part of the book focuses on the main biotechnological advancements for the understanding of the molecular mechanisms involved in the progression of various types of inflammatory diseases, highlighting up-to-date contributions of nanomedicine. The reader will be able to explore the utilization of technologies for various inflammatory diseases and will be able to enable an engaging and valuable knowledge for further research and clinically applied scenarios. 001461558 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed March 24, 2023). 001461558 650_0 $$aInflammation$$xTreatment. 001461558 650_0 $$aBiotechnology. 001461558 650_0 $$aNanomedicine. 001461558 655_0 $$aElectronic books. 001461558 7001_ $$aRibeiro de Araujo, Daniele. 001461558 7001_ $$aCarneiro-Ramos, Marcela. 001461558 77608 $$iPrint version:$$aRibeiro de Araujo, Daniele$$tBiotechnology Applied to Inflammatory Diseases$$dSingapore : Springer,c2023$$z9789811983412 001461558 830_0 $$aInterdisciplinary biotechnological advances. 001461558 852__ $$bebk 001461558 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-981-19-8342-9$$zOnline Access$$91397441.1 001461558 909CO $$ooai:library.usi.edu:1461558$$pGLOBAL_SET 001461558 980__ $$aBIB 001461558 980__ $$aEBOOK 001461558 982__ $$aEbook 001461558 983__ $$aOnline 001461558 994__ $$a92$$bISE