001461718 000__ 04564cam\a22005657a\4500 001461718 001__ 1461718 001461718 003__ OCoLC 001461718 005__ 20230503003407.0 001461718 006__ m\\\\\o\\d\\\\\\\\ 001461718 007__ cr\un\nnnunnun 001461718 008__ 230328s2023\\\\sz\a\\\\o\\\\\001\0\eng\d 001461718 020__ $$a9783031257025$$q(electronic bk.) 001461718 020__ $$a3031257022$$q(electronic bk.) 001461718 020__ $$z3031257014 001461718 020__ $$z9783031257018 001461718 0247_ $$a10.1007/978-3-031-25702-5$$2doi 001461718 035__ $$aSP(OCoLC)1374035566 001461718 040__ $$aYDX$$beng$$cYDX$$dGW5XE$$dEBLCP$$dOCLCF 001461718 049__ $$aISEA 001461718 050_4 $$aRB127 001461718 08204 $$a616/.0472$$223/eng/20230330 001461718 24500 $$aVisceral pain /$$cStuart M. Brierley, Nick J. Spencer, editors. 001461718 260__ $$aCham, Switzerland :$$bSpringer,$$c2023. 001461718 300__ $$a1 online resource (viii, 255 pages) :$$billustrations (chiefly color). 001461718 500__ $$aIncludes index. 001461718 5050_ $$aTools for optogenetic probing of nociceptive pathways; Monitoring activity -- An open science model to accelerate the generation, implementation and distribution of optogenetics and viral tools -- Vagal neuroinflammation accompanying respiratory viral infection: An overview of mechanisms and possible clinical significance -- Stress-induced Visceral Analgesia: Concept and Pathways -- Evidence of early life stress exposure and epigenetic modifications in functional chronic pain disorders -- EPIGENETIC REGULATION OF STRESS-INDUCED VISCERAL PAIN -- The biomechanics and mechanotransduction in visceral nociception -- VISCERAL NOCICEPTION IN GASTROINTESTINAL DISEASE -- Epithelial-Neuronal Communication in Visceral Pain -- Physiological Mechanisms Underpinning Heightened Perception of Visceral Afferent Signalling in Irritable Bowel Syndrome -- A fentanyl analogue that activates u-opioid receptors in acidified tissues inhibits colitis pain without opioid side effects -- Signalling in the Gut -- Translating colonic sensory afferent peripheral mechanosensitivity into the spinal cord dorsal horn -- Translating colonic afferent peripheral sensitivity into the spinal cord dorsal horn -- Neuron-Microglia Dynamic Duo in Chronic Abdominal Pain -- Pre-clinical Models of Endometriosis -- Spinal afferent innervation of the uterus -- Post-infectious bladder hypersensitivity in the development of Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS). 001461718 506__ $$aAccess limited to authorized users. 001461718 520__ $$aThe chapters in this book are based on the Visceral Pain conference in Adelaide, Australia, under the auspices of the International Federation for Neurogastroenterology and Motility in 2021. This is one of the hottest fields of science and includes mechanisms involving how the microbiome communicates with the brain and how, when disordered, these mechanisms contribute to clinical diseases such as Irritable Bowel Syndrome and Inflammatory Bowel Disease. Researchers from around the globe presented their latest findings as a review of the current state of the art in the field from both the clinical and scientific points of view. These systems are now appreciated as being critical for shaping our well-being and their disorders underlie chronic clinical conditions of significant morbidity and mortality. The author team includes long-established authorities who significantly contributed to the advances in visceral pain research over the past two decades and the new generation that will continue to contribute to advancing our understanding of the field. 001461718 588__ $$aDescription based on print version record. 001461718 650_0 $$aPain$$xResearch. 001461718 650_0 $$aViscera$$xDiseases. 001461718 650_0 $$aGastroenterology. 001461718 655_0 $$aElectronic books. 001461718 7001_ $$aBrierley, Stuart,$$eeditor. 001461718 7001_ $$aSpencer, Nick J.$$eeditor. 001461718 77608 $$iPrint version: $$z3031257014$$z9783031257018$$w(OCoLC)1360313807 001461718 852__ $$bebk 001461718 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-031-25702-5$$zOnline Access$$91397441.1 001461718 909CO $$ooai:library.usi.edu:1461718$$pGLOBAL_SET 001461718 980__ $$aBIB 001461718 980__ $$aEBOOK 001461718 982__ $$aEbook 001461718 983__ $$aOnline 001461718 994__ $$a92$$bISE