@article{1461741,
      recid = {1461741},
      author = {Macaluso, Matthew, and Preskorn, Sheldon, and Shelton,  Richard C.,},
      title = {Drug development in psychiatry /},
      pages = {1 online resource (519 pages) :},
      abstract = {This new book reviews clinical trial methodology as it  pertains to drug development in psychiatry. The authors  will describe the process of drug development in psychiatry  from discovery through marketing with the help of  clinically relevant examples. The history of drug  development in psychiatry is explored dating back to the  era of serendipitous discovery and culminating in an era of  new and highly focused targets. The book will delineate how  drug development in psychiatry has changed and adapted with  the discovery of drugs with novel mechanisms of action.  Drug Development in Psychiatry elucidates how biomarkers,  genetics, and advances in neuroscience and neuroimaging  have influenced drug development approaches, which will  ultimately change the practice of psychiatry. The book  charts the early years of drug discovery by chance  observation, reviews the developments of the past 50 years  of refined targeting of CNS drugs without the discovery of  mechanistically new drugs, and looks to the discovery of  mechanistically new drugs, the examination of new targets,  genetics, and biomarkers.},
      url = {http://library.usi.edu/record/1461741},
      doi = {https://doi.org/10.1007/978-3-031-21054-9},
}