001461784 000__ 04494cam\a22006017i\4500
001461784 001__ 1461784
001461784 003__ OCoLC
001461784 005__ 20230503003410.0
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001461784 008__ 230328s2023\\\\si\a\\\\o\\\\\000\0\eng\d
001461784 019__ $$a1373930097$$a1373986512
001461784 020__ $$a9789811977329$$q(electronic bk.)
001461784 020__ $$a9811977321$$q(electronic bk.)
001461784 020__ $$z9789811977312
001461784 020__ $$z9811977313
001461784 0247_ $$a10.1007/978-981-19-7732-9$$2doi
001461784 035__ $$aSP(OCoLC)1374131837
001461784 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dEBLCP$$dYDX$$dOCLCF
001461784 049__ $$aISEA
001461784 050_4 $$aRC268.4
001461784 08204 $$a616.994$$223/eng/20230328
001461784 24500 $$aGlycosignals in cancer :$$bmolecular assembly and recognition /$$cKoichi Furukawa, Minoru Fukuda, editors.
001461784 250__ $$aSecond edition.
001461784 264_1 $$aSingapore :$$bSpringer,$$c2023.
001461784 300__ $$a1 online resource (291 pages) :$$billustrations (black and white, and colour).
001461784 336__ $$atext$$btxt$$2rdacontent
001461784 337__ $$acomputer$$bc$$2rdamedia
001461784 338__ $$aonline resource$$bcr$$2rdacarrier
001461784 5050_ $$aPart I. Search for novel tumor epitopes related to carbohydrates -- Chapter 1.1. The ganglioside structures: chemistry and biochemistry -- Chapter 1.2. Fucosylated proteins as cancer biomarkers -- Part II. Assembly of glycoconjugates -- Chapter 2.1. Siglec-7 and synthetic sialylpolymer -- Chapter 2.2. Role of Sialyl-Tn antigen in Cancer Metastasis -- Chapter 2.3. Insights into the Role of Chondroitin Sulfate in Cancer -- Part III. Signaling pathways modulated by glycosylation -- Chapter 3.1. Significance of FUT8in pancreatic cancer and others -- Chapter 3.2. Effects of Bullfrog sialic acid-binding lectin in cancer cells -- Part IV. Interaction between carbohydrate and carbohydrate-recognizing molecules -- Chapter 4.1. Opposite functions of mono- and disialylated glycosphingolipids on the membrane of cancer cells -- Chapter 4.2. Tumor progression through interaction of mucins with lectins and subsequent signal transduction -- Part V. Clinical trials targeting glycosignals -- Chapter 5.1. Immunotherapy of Neuroblastoma Targeting GD2 and Beyond.
001461784 506__ $$aAccess limited to authorized users.
001461784 520__ $$aThis book, now in an extensively revised second edition, provides a comprehensive summary of the latest knowledge regarding glycosignals and a thorough analysis of their involvement in not only cancers but also other refractory conditions such as chronic inflammatory disorders. Many relevant topics are covered, including the search for novel tumor epitopes related to carbohydrates, the assembly of glycoconjugates, the modulation of signaling pathways by glycosylation, and interactions between complex carbohydrates and their recognition molecules. The role of various research approaches, for example advanced mass spectrometry, high-resolution imaging, and bioinformatics, is closely examined, and the results of novel therapeutic trials targeting glycosignals are discussed. The book will be essential reading for students and young researchers with an interest in glycoscience. In presenting new results and approaches and identifying areas for future research, it will also be of benefit for specialists in the field.
001461784 588__ $$aDescription based on print version record.
001461784 650_0 $$aCancer$$xMolecular aspects.
001461784 650_0 $$aGlycomics.
001461784 655_0 $$aElectronic books.
001461784 7001_ $$aFurukawa, Kōichi,$$cProfessor,$$eeditor.$$1https://isni.org/isni/0000000036371066
001461784 7001_ $$aFukuda, Minoru,$$d1945-$$eeditor.$$1https://isni.org/isni/0000000116602645
001461784 77608 $$iPrint version:$$tGlycosignals in cancer.$$bSecond edition.$$dSingapore : Springer Nature Singapore, 2023$$z9789811977312$$w(OCoLC)1356960363
001461784 852__ $$bebk
001461784 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-981-19-7732-9$$zOnline Access$$91397441.1
001461784 909CO $$ooai:library.usi.edu:1461784$$pGLOBAL_SET
001461784 980__ $$aBIB
001461784 980__ $$aEBOOK
001461784 982__ $$aEbook
001461784 983__ $$aOnline
001461784 994__ $$a92$$bISE