001461872 000__ 03898cam\a2200649\i\4500 001461872 001__ 1461872 001461872 003__ OCoLC 001461872 005__ 20230503003415.0 001461872 006__ m\\\\\o\\d\\\\\\\\ 001461872 007__ cr\cn\nnnunnun 001461872 008__ 230330s2023\\\\ne\a\\\\ob\\\\001\0\eng\d 001461872 019__ $$a1374190772 001461872 020__ $$a9789402411911$$q(electronic bk.) 001461872 020__ $$a9402411917$$q(electronic bk.) 001461872 020__ $$z9789402411904 001461872 020__ $$z9402411909 001461872 0247_ $$a10.1007/978-94-024-1191-1$$2doi 001461872 035__ $$aSP(OCoLC)1374244644 001461872 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dYDX$$dEBLCP 001461872 049__ $$aISEA 001461872 050_4 $$aRS165.C16 001461872 08204 $$a615.3/21$$223/eng/20230330 001461872 1001_ $$aRobinson, Brian,$$eauthor. 001461872 24514 $$aThe Calabar bean and its alkaloids :$$bfrom magic, via miracle, to memory /$$cBrian Robinson. 001461872 264_1 $$aDordrecht :$$bSpringer,$$c[2023] 001461872 264_4 $$c©2023 001461872 300__ $$a1 online resource (xxvi, 267 pages) :$$billustrations 001461872 336__ $$atext$$btxt$$2rdacontent 001461872 337__ $$acomputer$$bc$$2rdamedia 001461872 338__ $$aonline resource$$bcr$$2rdacarrier 001461872 504__ $$aIncludes bibliographical references and index. 001461872 5050_ $$aChronology -- Abbreviations -- Preface and acknowledgements -- 1. Introduction -- 2. l-Physostigmine (eserine) -- 3. l-Physovenine -- 4. l-Eseramine -- 5. l-N(8)-Norphysostigmine -- 6. l-Geneserine -- 7. 1H-, 13C- and 15N-Nuclear magnetic resonance spectra of the alkaloids of the Calabar bean -- 8. Other alkaloids of, as yet, unknown structures that have been isolated, or allegedly so, from the Calabar bean -- 9. Non-alkaloidal components of the Calabar bean -- 10. Biological activities of the alkaloids of the Calabar bean -- 11. Notes -- 12. References -- 13. Index. 001461872 506__ $$aAccess limited to authorized users. 001461872 520__ $$aInvestigations into Calabar beans (the dried ripe seeds of Physostigma venenosum) and their alkaloidal components compose a classical scientific journey throughout some one-and-a-half centuries and not only represent a fascinating aspect of the history of medicine but which is, moreover, still ongoing at the forefront of chemical and medical discovery. Those in particular involving its major such component, l-physostigmine, have led to an understanding of some of the fundamental mechanisms occurring in physiology, pharmacology and biochemistry and, either actually or potentially (by providing a template and thereby acting as a lead compound) have provided a useful treatment for a variety of neurological disorders associated with irregularities in cholinergic transmission in which augmentation of cholinergic activity has proved to be beneficial. 001461872 588__ $$aDescription based on print version record. 001461872 650_0 $$aCalabar bean$$xTherapeutic use. 001461872 650_0 $$aCalabar bean$$xAnalysis. 001461872 650_0 $$aMateria medica, Vegetable. 001461872 650_0 $$aBotanical chemistry. 001461872 650_6 $$aPhytothérapie.$$0(CaQQLa)201-0029328 001461872 650_6 $$aChimie végétale.$$0(CaQQLa)201-0004280 001461872 655_0 $$aElectronic books. 001461872 77608 $$iPrint version:$$aRobinson, Brian.$$tCalabar bean and its alkaloids.$$dDordrecht : Springer, 2022$$z9789402411904$$w(OCoLC)1295150478 001461872 852__ $$bebk 001461872 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-94-024-1191-1$$zOnline Access$$91397441.1 001461872 909CO $$ooai:library.usi.edu:1461872$$pGLOBAL_SET 001461872 980__ $$aBIB 001461872 980__ $$aEBOOK 001461872 982__ $$aEbook 001461872 983__ $$aOnline 001461872 994__ $$a92$$bISE