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Title
Engineering and physical approaches to cancer / Ian Y. Wong, Michelle R. Dawson, editors.
ISBN
9783031228025 (electronic bk.)
3031228022 (electronic bk.)
3031228014
9783031228018
Published
Cham, Switzerland : Springer, 2023.
Language
English
Description
1 online resource (500 pages)
Other Standard Identifiers
10.1007/978-3-031-22802-5 doi
Call Number
RC270.8
Dewey Decimal Classification
616.99/406
Summary
Engineering and Physical Approaches to Cancer addresses the newest research at this interface between cancer biology and the physical sciences. Several chapters address the mechanobiology of collective and individual cell migration, including experimental, theoretical, and computational perspectives. Other chapters consider the crosstalk of biological, chemical, and physical cues in the tumor microenvironment, including the role of senescence, polyploid giant cells, TGF-beta, metabolism, and immune cells. Further, chapters focus on circulating tumor cells and metastatic colonization, highlighting both bioengineered models as well as diagnostic technologies. Further, this book features the work of emerging and diverse investigators in this field, who have already made impressive cross-disciplinary scientific contributions. This book is designed for a general audience, particularly researchers conversant in cancer biology but less familiar with engineering (and vice-versa). Thus, we envision that this book will be suitable for faculty, postdoctoral fellows, and advanced graduate students across medicine, biological sciences, and engineering. We also anticipate this book will be of interest to medical professionals and trainees, as well as researchers in the pharmaceutical and biomedical device industry.
Note
Includes index.
Access Note
Access limited to authorized users.
Source of Description
Description based on print version record.
Series
Current cancer research.
Chapter 1. EMT
Chapter 2. Nuclear/Chromatin Mechanics
Chapter 3. Cell level mechanical changes
Chapter 4. Physical aspects related to metabolism
Chapter 5. Mechanical tropism / Physical aspects of seed and soil
Chapter 6. Tumor microenvironment interactions
Chapter 7. Extracellular Matrix
Chapter 8. Physical Assays Focused on Tumor Heterogeneity
Chapter 9. Ecology / evolution of the tumor microenvironment
Chapter 10. Spatial transcriptomics / proteomics in the Human Tumor Atlas.