001463330 000__ 04210cam\a22006377i\4500 001463330 001__ 1463330 001463330 003__ OCoLC 001463330 005__ 20230601003316.0 001463330 006__ m\\\\\o\\d\\\\\\\\ 001463330 007__ cr\cn\nnnunnun 001463330 008__ 230419s2023\\\\sz\\\\\\o\\\\\001\0\eng\d 001463330 019__ $$a1376165014 001463330 020__ $$a9783031228025$$q(electronic bk.) 001463330 020__ $$a3031228022$$q(electronic bk.) 001463330 020__ $$z3031228014 001463330 020__ $$z9783031228018 001463330 0247_ $$a10.1007/978-3-031-22802-5$$2doi 001463330 035__ $$aSP(OCoLC)1376457714 001463330 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dYDX$$dUKAHL 001463330 049__ $$aISEA 001463330 050_4 $$aRC270.8 001463330 08204 $$a616.99/406$$223/eng/20230419 001463330 24500 $$aEngineering and physical approaches to cancer /$$cIan Y. Wong, Michelle R. Dawson, editors. 001463330 264_1 $$aCham, Switzerland :$$bSpringer,$$c2023. 001463330 300__ $$a1 online resource (500 pages) 001463330 336__ $$atext$$btxt$$2rdacontent 001463330 337__ $$acomputer$$bc$$2rdamedia 001463330 338__ $$aonline resource$$bcr$$2rdacarrier 001463330 4901_ $$aCurrent cancer research 001463330 500__ $$aIncludes index. 001463330 5050_ $$aChapter 1. EMT -- Chapter 2. Nuclear/Chromatin Mechanics -- Chapter 3. Cell level mechanical changes -- Chapter 4. Physical aspects related to metabolism -- Chapter 5. Mechanical tropism / Physical aspects of seed and soil -- Chapter 6. Tumor microenvironment interactions -- Chapter 7. Extracellular Matrix -- Chapter 8. Physical Assays Focused on Tumor Heterogeneity -- Chapter 9. Ecology / evolution of the tumor microenvironment -- Chapter 10. Spatial transcriptomics / proteomics in the Human Tumor Atlas. 001463330 506__ $$aAccess limited to authorized users. 001463330 520__ $$aEngineering and Physical Approaches to Cancer addresses the newest research at this interface between cancer biology and the physical sciences. Several chapters address the mechanobiology of collective and individual cell migration, including experimental, theoretical, and computational perspectives. Other chapters consider the crosstalk of biological, chemical, and physical cues in the tumor microenvironment, including the role of senescence, polyploid giant cells, TGF-beta, metabolism, and immune cells. Further, chapters focus on circulating tumor cells and metastatic colonization, highlighting both bioengineered models as well as diagnostic technologies. Further, this book features the work of emerging and diverse investigators in this field, who have already made impressive cross-disciplinary scientific contributions. This book is designed for a general audience, particularly researchers conversant in cancer biology but less familiar with engineering (and vice-versa). Thus, we envision that this book will be suitable for faculty, postdoctoral fellows, and advanced graduate students across medicine, biological sciences, and engineering. We also anticipate this book will be of interest to medical professionals and trainees, as well as researchers in the pharmaceutical and biomedical device industry. 001463330 588__ $$aDescription based on print version record. 001463330 650_0 $$aCancer$$xTreatment. 001463330 650_0 $$aCancer$$xImaging. 001463330 650_0 $$aBiomechanics. 001463330 655_0 $$aElectronic books. 001463330 7001_ $$aWong, Ian Y.$$eeditor. 001463330 7001_ $$aDawson, Michelle R.$$eeditor. 001463330 77608 $$iPrint version:$$tENGINEERING AND PHYSICAL APPROACHES TO CANCER.$$d[Place of publication not identified] : SPRINGER INTERNATIONAL PU, 2023$$z3031228014$$w(OCoLC)1350417595 001463330 830_0 $$aCurrent cancer research. 001463330 852__ $$bebk 001463330 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-031-22802-5$$zOnline Access$$91397441.1 001463330 909CO $$ooai:library.usi.edu:1463330$$pGLOBAL_SET 001463330 980__ $$aBIB 001463330 980__ $$aEBOOK 001463330 982__ $$aEbook 001463330 983__ $$aOnline 001463330 994__ $$a92$$bISE