001463389 000__ 04910cam\a22005897i\4500
001463389 001__ 1463389
001463389 003__ OCoLC
001463389 005__ 20230601003318.0
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001463389 008__ 230421s2023\\\\si\\\\\\o\\\\\000\0\eng\d
001463389 019__ $$a1376233090
001463389 020__ $$a9789819903139$$q(electronic bk.)
001463389 020__ $$a9819903130$$q(electronic bk.)
001463389 020__ $$z9819903122
001463389 020__ $$z9789819903122
001463389 0247_ $$a10.1007/978-981-99-0313-9$$2doi
001463389 035__ $$aSP(OCoLC)1376833469
001463389 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dYDX$$dUKAHL$$dYDX
001463389 049__ $$aISEA
001463389 050_4 $$aRC103.A4$$bH97 2023
001463389 08204 $$a616.9/94$$223/eng/20230421
001463389 24500 $$aHypoxia in cancer :$$bsignificance and impact on cancer therapy /$$cSukhes Mukherjee, Jagat Rakesh Kanwar, editors.
001463389 264_1 $$aSingapore :$$bSpringer,$$c2023.
001463389 300__ $$a1 online resource (488 pages) :$$billustrations (black and white, and color).
001463389 336__ $$atext$$btxt$$2rdacontent
001463389 337__ $$acomputer$$bc$$2rdamedia
001463389 338__ $$aonline resource$$bcr$$2rdacarrier
001463389 5050_ $$aChapter 1. Hypoxia and its Biological Implications for Cancer Therapy -- Chapter 2. Hypoxia's function in cancer -- Chapter 3. Role of Hypoxia and Reactive Oxygen Species in cancer biology -- Chapter 4. Hypoxic tumor microenvironment: driver for cancer progression -- Chapter 5. Hypoxia and Senescence: Role of Oxygen in Modulation of Tumor Suppression -- Chapter 6. Hypoxia Regulated Gene Expression and Metastasis -- Chapter 7. piRNA based cancer therapy in hypoxic tumor -- Chapter 8. MicroRNA Signatures of Tumor Hypoxia -- Chapter 9. Hypoxia and the Metastatic Cascade -- Chapter 10. Hypoxia and Extra Cellular Matrix-major drivers of tumor Metastasis -- Chapter 11. Role of Hypoxia in Cancer Therapy Introduction -- Chapter 12. Hypoxic regulation of telomerase gene expression in cancer -- Chapter 13. CRISPR/Cas9-editing-based modeling of tumor hypoxia -- Chapter 14. Tumor-on-a-chip: Microfluidic models for Hypoxic tumor microenvironment -- Chapter 15. Imaging the Hypoxic Tumor microenvironment in cancer models -- Chapter 16. Hypoxia-targeting drugs as new cancer chemotherapy agents Hypoxia-targeting drugs as new cancer chemotherapy agents - Molecular Insights -- Chapter 17. Identification of Hypoxia targeting drugs in the tumor microenvironment and prodrug Strategies for Targeting Tumor Hypoxia -- Chapter 18. Hypoxia Induced Apoptosis in Cancer Development -- Chapter 19. Hypoxia in drug resistance and radioresistance.
001463389 506__ $$aAccess limited to authorized users.
001463389 520__ $$aThis book reviews the central role of hypoxia in cancer initiation and progression. It discusses the mechanisms of hypoxia in chemoresistance, radioresistance, angiogenesis, vasculogenesis, metastasis, metabolic, and genomic instability. It also explores the potential of hypoxia in the diagnosis and treatment of cancer. The book provides an overview of hypoxia imaging, its biological relevance, and mechanism of action. It helps in understanding the molecular mechanisms of the regulation of senescence by hypoxia. It explores the contribution of hypoxia to immune resistance and immune suppression/tolerance and determines the hypoxia-responsive long non-coding RNAs in regulating hypoxic gene expression at chromatin, transcriptional, and post-transcriptional levels. Further, it presents the functional link between hypoxia and miRNA expressions and hypoxia-regulated miRNAs in cancer cell survival in a low oxygen environment. Lastly, it discusses the applications of tumor-on-a-chip technology for the understanding of hypoxia-tumor microenvironment. This book is a valuable source for oncologists and scientists working to understand the role of hypoxia in cancer and therapeutic approaches.
001463389 588__ $$aDescription based on print version record.
001463389 650_0 $$aAnoxemia.
001463389 650_0 $$aCancer.
001463389 655_0 $$aElectronic books.
001463389 7001_ $$aMukherjee, Sukhes,$$eeditor.
001463389 7001_ $$aKanwar, Jagat Rakesh,$$eeditor.
001463389 77608 $$iPrint version:$$tHYPOXIA IN CANCER.$$d[Place of publication not identified] : SPRINGER VERLAG, SINGAPOR, 2023$$z9819903122$$w(OCoLC)1363103788
001463389 852__ $$bebk
001463389 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-981-99-0313-9$$zOnline Access$$91397441.1
001463389 909CO $$ooai:library.usi.edu:1463389$$pGLOBAL_SET
001463389 980__ $$aBIB
001463389 980__ $$aEBOOK
001463389 982__ $$aEbook
001463389 983__ $$aOnline
001463389 994__ $$a92$$bISE