Bayesian adaptive design for immunotherapy and targeted therapy / Haitao Pan, Ying Yuan.
2023
RM276
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Title
Bayesian adaptive design for immunotherapy and targeted therapy / Haitao Pan, Ying Yuan.
Author
ISBN
9789811981760 (electronic bk.)
9811981760 (electronic bk.)
9811984670
9789811984679
9789811981746
9811981744
9811981760 (electronic bk.)
9811984670
9789811984679
9789811981746
9811981744
Published
Singapore : Springer, [2023]
Copyright
©2023
Language
English
Description
1 online resource (xi, 262 pages) : illustrations (some color)
Item Number
10.1007/978-981-19-8176-0 doi
Call Number
RM276
Dewey Decimal Classification
615.3/70151
Summary
This book provides a comprehensive review of novel adaptive trial designs for targeted therapies and immunotherapies. This book covers a wide range of novel statistical designs for various clinical settings, including early phase dose-escalation study, proof-of-concept trials, and confirmatory studies with registrational. The book includes real-life examples and software to facilitate practitioners to learn and use the designs in practice.
Bibliography, etc. Note
Includes bibliographical references.
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Access limited to authorized users.
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Table of Contents
Introduction to Adaptive Design and Delayed Outcomes
Basics of Bayesian Statistics
Phase I Dose-finding Design
Phase II Design for Interim Monitoring
Phase I-II Dose-finding Design
Drug Combination Trial Design
Conclusion.
Basics of Bayesian Statistics
Phase I Dose-finding Design
Phase II Design for Interim Monitoring
Phase I-II Dose-finding Design
Drug Combination Trial Design
Conclusion.