Endolysosomal voltage-dependent cation channels / Christian Wahl-Schott, Martin Biel, editors.
Wahl-Schott, Christian, editor.; Biel, Martin, editor.
2023
QH603.I54 E53 2023
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Title
Endolysosomal voltage-dependent cation channels / Christian Wahl-Schott, Martin Biel, editors.
ISBN
9783031315237 (electronic bk.)
3031315235 (electronic bk.)
3031315227
9783031315220
DOI
https://doi.org/10.1007/978-3-031-31523-7
Published
Cham : Springer, [2023]
Language
English
Description
1 online resource (310 p.).
Item Number
10.1007/978-3-031-31523-7 doi
Call Number
QH603.I54 E53 2023
Dewey Decimal Classification
571.6/4
Summary
This book covers the molecular structures and the cellular and in vivo function of endosomes and lysosomes, i.e. intracellular vesicles which are involved in many cellular processes such as endocytosis, intracellular trafficking, degradation of material from inside (e.g. autophagy) and outside the cell as well as exocytosis. Membranes of endolysosomal organelles contain an amazing number and diversity of ion channels. These ion channels are the topic of the present book that focusses on describing the structure, the biophysical properties, physiological functions of endolysosomal ion channels at the molecular, cellular and in vivo level.
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Access limited to authorized users.
Source of Description
Online resource; title from PDF title page (SpringerLink, viewed May 4, 2023).
Added Author
Wahl-Schott, Christian, editor.
Biel, Martin, editor.
Series
Handbook of experimental pharmacology ; v. 278.
Available in Other Form
Endolysosomal Voltage-Dependent Cation Channels
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Part I: Physiological Functions of Endo-lysosomal Cation Channels
NAADP-Mediated Ca2+ Signalling
NAADP-Dependent TPC Current
NAADP-Evoked Ca2+ Signaling: The DUOX2���HN1L/JPT2���Ryanodine Receptor 1 Axis
TPC Functions in the Immune System
Lysosomal Ion Channels and Lysosome��� 1 Organelle Interactions
TRPML1 and TFEB, an Intimate Affair
Lysosomal Potassium Channels
Part II Structure and Composition of TPC and TRPML Channels
Structure and Function of Plant and Mammalian TPC Channels
A Structural Overview of TRPML1 and the TRPML Family
Endo-Lysosomal Two-Pore Channels and Their Protein Partners
Part III: Tools and Methods to Characterize Endolysosomal Cation Channels
Electrophysiological Techniques on the Study of Endolysosomal Ion Channels
The Plant Vacuole as Heterologous System to Characterize the Functional Properties of TPC Channels
Expanding the Toolbox: Novel Modulators of Endolysosomal Cation Channels
Characterization of Endo-Lysosomal Cation Channels Using Calcium Imaging.

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