001463704 000__ 04175cam\a2200601\i\4500
001463704 001__ 1463704
001463704 003__ OCoLC
001463704 005__ 20230601003333.0
001463704 006__ m\\\\\o\\d\\\\\\\\
001463704 007__ cr\un\nnnunnun
001463704 008__ 230506s2023\\\\si\a\\\\ob\\\\000\0\eng\d
001463704 019__ $$a1378093243
001463704 020__ $$a9789811985201$$qelectronic book
001463704 020__ $$a9811985200$$qelectronic book
001463704 020__ $$z9811985197
001463704 020__ $$z9789811985195
001463704 0247_ $$a10.1007/978-981-19-8520-1$$2doi
001463704 035__ $$aSP(OCoLC)1378389099
001463704 040__ $$aEBLCP$$beng$$erda$$cEBLCP$$dYDX$$dGW5XE$$dNOC$$dEBLCP$$dYDX
001463704 049__ $$aISEA
001463704 050_4 $$aRM666.N87$$bN83 2023
001463704 08204 $$a611/.01816$$223/eng/20230516
001463704 24500 $$aNucleic acid biology and its application in human diseases /$$cSubhrangsu Chatterjee, Samit Chattopadhyay, editors.
001463704 264_1 $$aSingapore :$$bSpringer,$$c[2023]
001463704 300__ $$a1 online resource (xii, 416  pages) :$$billustrations (some color)
001463704 336__ $$atext$$btxt$$2rdacontent
001463704 337__ $$acomputer$$bc$$2rdamedia
001463704 338__ $$aonline resource$$bcr$$2rdacarrier
001463704 504__ $$aIncludes bibliographical references.
001463704 5050_ $$aChapter 1. Nucleic Acid Structure and biology -- Chapter 2 . Nucleic acid-mediated inflammatory diseases -- Chapter 3. Alternative splicing and cancer -- Chapter 4. Nucleic acid-based strategies to treat neurodegenerative movement -- Chapter 5. Human Diseases induced by Oxidative damage in DNA -- Chapter 6. Nucleic Acid in Nanotechnology -- Chapter 7. Nucleic Acid in Diagnostics -- Chapter 8. Nucleic Acid sensors and logic gates -- Chapter 9. Nucleic Acid Therapeutics in Cancer Biology -- Chapter 10. RNA vaccines -- Chapter 11. Nucleic Acid Editing.
001463704 506__ $$aAccess limited to authorized users.
001463704 520__ $$aThis book reviews the structure-function relationship of nucleic acids, their role in the pathophysiology of the diseases, and as therapeutic targets for human diseases. The chapters discuss the role of nucleic acids in inflammatory diseases, neurodegenerative diseases, and cancer. The book also describes recent advancements in nucleic acid-based therapy, the application of nucleic acids in diagnostics, in the development of nano-carriers, logic gates, and sensors. It explores the use of nucleic acids (RNA and DNA) as a unique and multifunctional platform for numerous applications, including therapeutics, diagnostics, nanodevices, and materials. It further examines the role of DNA methylation, histone modifiers and readers, chromatin remodelers, microRNAs, and other components of chromatin in the progression of cancer. The book also discusses the applications of nucleic acid as a vaccine and as a gene-editing tool. It also provides an overview of the clinical trials using genome editing platforms for disease treatment and the challenges in implementing the editing technology. Finally, the book elucidates a representative description of challenges associated with nucleic acid-mediated therapy.
001463704 588__ $$aDescription based on online resource; title from digital title page (viewed on May 16, 2023).
001463704 650_0 $$aNucleic acids$$xTherapeutic use.
001463704 650_0 $$aDiseases.
001463704 655_0 $$aElectronic books.
001463704 7001_ $$aChatterjee, Subhrangsu,$$eeditor.
001463704 7001_ $$aChattopadhyay, Samit,$$eeditor.
001463704 77608 $$iPrint version:$$aChatterjee, Subhrangsu$$tNucleic Acid Biology and Its Application in Human Diseases$$dSingapore : Springer,c2023$$z9789811985195
001463704 852__ $$bebk
001463704 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-981-19-8520-1$$zOnline Access$$91397441.1
001463704 909CO $$ooai:library.usi.edu:1463704$$pGLOBAL_SET
001463704 980__ $$aBIB
001463704 980__ $$aEBOOK
001463704 982__ $$aEbook
001463704 983__ $$aOnline
001463704 994__ $$a92$$bISE