Intro
Foreword
Preface
Contents
1: Introduction to Diagnosis and Treatment in Pancreatic Neoplasms
1.1 The Environment for Nihilism in Pancreatic Cancer
1.2 Key Points in the Diagnosis of Pancreatic Cancer
1.2.1 Molecular Diagnosis: Toward the Early Diagnosis in Pancreatic Cancer
1.2.2 Radiomics: Diagnostic Imaging as a Tool for Pathological Specification and Prognosis in Pancreatic Cancer
1.3 Key Points in the Treatment of Pancreatic Cancer
1.3.1 Medical Treatment: Personalized and Precision Therapy in Pancreatic Cancer

1.3.2 The Surgical Approach as a Guarantor of the Locoregional Eradication of Pancreatic Cancer
References
2: Pancreatic Cystic Neoplasms: Serous Cystadenoma, Mucinous Cystadenoma
2.1 Serous Cystadenoma
2.2 Mucinous Cystic Neoplasia (MCN) (Tables 2.2 and 2.3)
References
3: Intraductal Papillary Mucinous Tumors Principal and Lateral Branch of IPMT: Preoperative Management, Surgical Indications, and Surgical Techniques
3.1 Definition
3.2 Epidemiology
3.3 Classification
3.4 Pathogenesis
3.5 Clinical Presentation
3.6 Diagnostic Approach

3.7 Clinical and Surgical Management According to Published Guidelines
References
4: Pancreatic Neuroendocrine Tumors: Diagnosis, Management, and Intraoperative Techniques
4.1 Background
4.2 Diagnosis of pNETs: Imagining and Histological Diagnosis
4.2.1 Imaging Studies
4.2.1.1 Ultrasound (US)
4.2.1.2 Computed Tomography
4.2.1.3 Magnetic Resonance Imaging
4.2.1.4 Endoscopic Ultrasonography
4.2.1.5 Somatostatin Receptor-Based Imaging and Positron Emission Tomography
4.2.2 Histological Diagnosis
4.3 Classification
4.4 Neuroendocrine Syndromes

4.4.1 Functioning Pancreatic Neuroendocrine Tumors
4.4.1.1 Insulinoma
4.4.1.2 Gastrinoma
4.4.1.3 VIPoma
4.4.1.4 Glucagonoma
4.4.2 Non-functioning Pancreatic Neuroendocrine Tumors
4.5 Localized pNETs Management
4.5.1 How Should Small Non-functioning (NF) pNETs Be Treated?
4.5.2 How Should Functional Lesions Be Treated?
4.5.3 What Is the Role of Parenchymal-Sparing Surgical Techniques (PSRs)?
4.5.4 What Is the Role of Splenic Preservation During DP as the Management of pNETs?
4.5.5 What Is the Role of Lymphadenectomy in pNETs?

4.5.6 What Is the Role of Minimally Invasive Surgery in the Treatment of pNETs?
4.5.7 How Should We Manage pNETs in MEN1 Syndrome and Other Familial Diseases?
4.6 Management of Metastatic pNETS
4.6.1 Primary Tumor Resection in Patients with Metastatic PNET
4.6.2 Hepatic Cytoreduction
4.6.3 Liver Transplantation
4.6.4 Combined Pancreatectomy and Liver Debulking
4.6.5 Removing Primary Tumor When Unresectable Metastatic Disease Is Present
4.6.6 Primary Tumor Resection or Hepatic Cytoreduction When There Is Extrahepatic Disease
4.7 Systemic Therapy