Free Radical Biology of and Endocrine, Metabolic Immune Disorders. Free radical biology of and endocrine, metabolic immune disorders / edited by Asis Bala.
2022
QP514.2 .F744 2022
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Title
Free Radical Biology of and Endocrine, Metabolic Immune Disorders.
Free radical biology of and endocrine, metabolic immune disorders / edited by Asis Bala.
Free radical biology of and endocrine, metabolic immune disorders / edited by Asis Bala.
Author
Edition
1st ed.
ISBN
9789815049237
9789815049220
9789815049220
Published
Singapore : Bentham Science Publishers Pte. Ltd., [2022]
Copyright
©2022
Language
English
Description
1 online resource (147 pages) : illustrations.
Call Number
QP514.2 .F744 2022
Dewey Decimal Classification
574.192
Summary
This reference explores the science of signaling mechanisms associated with diseases like endocrine, metabolic and immune disorders which are linked to oxidative stress mediated disease mechanisms. The common diseases in these categories include diabetes mellitus and arthritis and conditions defined by inflammation and autoimmunity. These diseases involve metabolic pathways mediated by reactive oxygen species or free radicals. The pathways are targets in the mechanism of drugs which aim to treat related disorders. The book covers key topics in free radical biology that help to understand the nature of the pathways and the pharmacology of the drugs that are designed to target them.5 chapters elucidate the free radical biology of the diseases.1. Role of free radical biology in diabetes mellitus2. Role of GSK3 in regulation of insulin release and glucose metabolism3. Regulatory role of NRF2 in rheumatoid arthritis4. Role of free radical biology in Alzheimer's disease5. Regulatory role of immune cells mediated antibody on rheumatoid arthritis Key features:- Elucidates the key biochemical and pharmacological mechanisms that are mediated by free radicals in common endocrine, metabolic and immune diseases- Explains the activation of immunological factors (like RF and ACPA) that trigger inflammation and arthritis- Covers the role of free radicals in Alzheimer's disease and new interventions that target mitochondrial mechanisms- Systematically explains the molecular biology of free radicals with the help of schematic diagrams - Includes references for further reading The accessible and structured text in this reference make it a suitable resource for all biomedical scientists, faculty and postgraduate students in academia and industry.
Bibliography, etc. Note
Includes bibliographical references.
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Access limited to authorized users.
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