The molecular basis of human cancer / edited by William B. Coleman and Gregory J. Tsongalis.
Coleman, William B.; Tsongalis, Gregory J.
2002
RC268.5 .M6335 2002
Available Online

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Title The molecular basis of human cancer / edited by William B. Coleman and Gregory J. Tsongalis.
ISBN 9781592591251 (electronic bk.)
1592591256 (electronic bk.)
9781617371073 (print)
1617371076 (print)
9781597454582
1597454583
0896036340 (alk. paper)
9780896036345 (alk. paper)
DOI https://doi.org/10.1007/978-1-59259-125-1
Publication Details Totowa, N.J. : Humana Press, ©2002.
Language English
Description 1 online resource (xii, 588 pages) : illustrations
Item Number 10.1007/978-1-59259-125-1 doi
Call Number RC268.5 .M6335 2002
Dewey Decimal Classification 616.99/4042
Summary Molecular biology holds great promise for the development of new strategies for cancer prevention and treatment. In The Molecular Basis of Human Cancer, internationally renowned basic and clinical scientists provide an account of our best current understanding of the genetics of cancer. These authoritative contributors describe in detail each of the known molecular mechanisms governing neoplastic transformation in the breast, prostate, lung, liver, colon, skin, and in the leukemias and lymphomas. Their discussion illuminates both recent developments and established concepts in epidemiology, molecular techniques, oncogenesis, and mutation mechanisms, as well as the chemical, viral, and physical mechanisms of cancer induction. They also consider the future directions of research, including discussions of the exploitation of molecular targets for developing anticancer drugs, recent developments in gene therapy, and the appropriate use of molecular information in genetic counseling. Up-to-date and forward-looking, The Molecular Basis of Human Cancer offers a critically integrated survey of the full range of state-of-the-art cancer molecular biology and genetics and constitutes indispensable reading for all cancer researchers today.
Bibliography, etc. Note Includes bibliographical references and index.
Access Note Restrictions unspecified
Access limited to authorized users.
System Details Note Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. (http://purl.oclc.org/DLF/benchrepro0212)
Digital File Characteristics text file
PDF
Source of Description Description based on print version record.
Added Author Coleman, William B.
Tsongalis, Gregory J.
Available in Other Form Molecular basis of human cancer.
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Ch. 1. Cancer epidemiology: incidence and etiology of human neoplasms
Ch. 2. Essential concepts and techniques in molecular biology
Ch. 3. Cancer genes
Ch. 4. Positive mediators of cell proliferation in neoplastic transformation
Ch. 5. Inactivation of negative growth regulators during neoplastic transformation
Ch. 6. The role of genomic instability in the development of human cancer
Ch. 7. Chromosomes and chromosomal instability in human cancer
Ch. 8. Hereditary cancer
Ch. 9. Evolution of research in cancer etiology
Ch. 10. Cellular responses to chemical carcinogens
Ch. 11. Physical agents in human carcinogenesis
Ch. 12. Viral mechanisms of human carcinogenesis
Ch. 13. The molecular biology of colorectal carcinoma: importance of the Wg/Wnt signal transduction pathway
Ch. 14. Molecular genetic alterations in primary hepatocellular neoplasms: hepatocellular adenoma, hepatocellular carcinoma, and hepatoblastoma
Ch. 15. The molecular basis of breast carcinogenesis
Ch. 16. The molecular basis of prostate carcinogenesis
Ch. 17. The molecular basis of lung carcinogenesis
Ch. 18. The molecular basis of skin carcinogenesis
Ch. 19. The molecular biology of leukemias
Ch. 20. Molecular genetic applications to the diagnosis of Non-Hodgkin's lymphoma
Ch. 21. Cancer genetic counseling
Ch. 22. Molecular genetic diagnosis of inherited cancer predisposition
Ch. 23. Novel molecular targets for cancer drug discovery
Ch. 24. Gene therapy in the treatment of human cancer.

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