001467774 000__ 07116cam\\22006137a\4500 001467774 001__ 1467774 001467774 003__ OCoLC 001467774 005__ 20230707003338.0 001467774 006__ m\\\\\o\\d\\\\\\\\ 001467774 007__ cr\un\nnnunnun 001467774 008__ 230506s2023\\\\sz\\\\\\ob\\\\000\0\eng\d 001467774 019__ $$a1378295493 001467774 020__ $$a9783031263224$$q(electronic bk.) 001467774 020__ $$a3031263227$$q(electronic bk.) 001467774 020__ $$z3031263219 001467774 020__ $$z9783031263217 001467774 0247_ $$a10.1007/978-3-031-26322-4$$2doi 001467774 035__ $$aSP(OCoLC)1378391564 001467774 040__ $$aEBLCP$$beng$$cEBLCP$$dYDX$$dGW5XE 001467774 049__ $$aISEA 001467774 050_4 $$aQR171.I6 001467774 08204 $$a616.3/401$$223/eng/20230516 001467774 1001_ $$aBlachier, François. 001467774 24510 $$aMetabolism of alimentary compounds by the intestinal microbiota and health /$$cFrançois Blachier. 001467774 260__ $$aCham :$$bSpringer,$$c2023. 001467774 300__ $$a1 online resource (265 p.) 001467774 500__ $$a4.3 Dietary Compounds, Bacterial Metabolites, and Diarrhea 001467774 504__ $$aIncludes bibliographical references. 001467774 5050_ $$aIntro -- Preface -- Acknowledgments -- Contents -- About the Author -- 1: Physiological and Metabolic Functions of the Intestinal Epithelium: From the Small to the Large Intestine -- 1.1 The Intestine Displays Multiple Physiological Functions in Addition to Absorption of Components Originating from Food -- 1.2 The Intestinal Epithelium Represents a Border Between the Outdoor and the Internal Environment -- 1.3 Structure and Functions of the Small Intestine Epithelium: Metabolism of Nutrients in Epithelial Cells 001467774 5058_ $$a1.4 Structure and Functions of the Large Intestine Epithelium: Metabolism of Nutrients in the Colonocytes -- References -- 2: Intestine Offers Board and Lodging for Intestinal Microbes on a Short- or Long-Term Stay -- 2.1 The Human Intestinal Microbiota: A Complex Mixture -- 2.2 Bacteria Concentration, Composition, and Diversity During the Whole Life -- References -- 3: Metabolism of Dietary Substrates by Intestinal Bacteria and Consequences for the Host Intestine -- 3.1 Metabolism of Proteins and Amino Acids by the Intestinal Microbiota and Impact on the Intestinal Epithelium Metabolism and... 001467774 5058_ $$aAmino Acid-Derived Bacterial Metabolites and Effects on the Intestinal Epithelium -- Effects of the Amounts of Dietary Proteins on the Intestinal Ecosystem and Consequences -- 3.2 Metabolism of Polysaccharides by the Intestinal Microbiota and Impact on the Intestinal Epithelium Metabolism and Functions -- Polysaccharide-Derived Bacterial Metabolites and Effects on the Intestinal Epithelium -- Effects of the Amount of Dietary Polysaccharide on the Intestinal Ecosystem and Consequences -- 3.3 Metabolism of Lipids by the Intestinal Microbiota 001467774 5058_ $$aLipid-Derived Bacterial Metabolites and Effects on the Intestinal Ecosystem -- Effects of the Amount of Dietary Lipids on the Intestinal Ecosystem and Consequences -- 3.4 Metabolism of Purine Nucleotide by the Intestinal Microbiota -- 3.5 Metabolism of Phytochemicals by the Intestinal Microbiota and Impact on the Intestinal Epithelium Metabolism and Functions -- 3.6 Osmolality and pH of the Intestinal Luminal Fluid and Effects on the Intestinal Epithelium -- 3.7 Bacterial Metabolites and the Intestinal Immune System 001467774 5058_ $$a3.8 Minerals and the Intestinal Microbiota: Consequences for the Intestinal Ecosystem -- 3.9 Vitamins and the Intestinal Microbiota: Consequences for the Intestinal Ecosystem -- 3.10 Food Additives and Compounds Produced during Cooking Processes and the Intestinal Microbiota: Consequences for the Intest... -- References -- 4: Alimentation, Bacterial Metabolites, and Host Intestinal Epithelium -- 4.1 Dietary Compounds, Bacterial Metabolites, and Mucosal Inflammation and Subsequent Healing -- 4.2 Dietary Compounds, Bacterial Metabolites, and Colorectal Cancer 001467774 506__ $$aAccess limited to authorized users. 001467774 520__ $$aThis book provides an overview of the metabolism of dietary compounds by the intestinal microbiota, and on the consequences of such metabolic activity on host metabolism and physiological functions; both in intestinal and peripheral tissues. Over the last years, our understanding of the causal links between microbiota metabolic activity towards dietary and endogenous substrates and human health status has evolved extensively. In this context, the book starts with a comprehensive introduction devoted to the physiological and metabolic functions of the intestinal epithelium, followed by a part dedicated to the way intestine offers board and lodging for microbes being on a short- or long-term stay. The next chapters focus on the utilization of the available substrates from diet by the intestinal bacteria to produce numerous bacterial metabolites, and on the impact of such microbial activity, in the first place for communication between microbes, and for communication between microbes and lodging host. As will be detailed, this latter process of interkingdom communication leads to either beneficial or deleterious effects on intestinal physiology and metabolism. Special attention is given to selected pathophysiological processes namely chronic intestinal inflammation, colorectal carcinogenesis, and diarrhea. Then, the effects of modifications of bacterial metabolites and other bioactive compounds by the host after intestinal absorption, and consequences for peripheral tissue functions are presented. Summarizing the state of the art on what is known about the metabolic crosstalk between gut microbiota and human metabolism, as well as perspectives for further experimental and clinical research, this book provides a useful resource for researchers, professionals, and students with a background in biology, and/or nutrition, medicine, pharmacology, and for those which are involved in the agriculture and food production. By explaining technical terms all along the text, this book should be understandable also for interested non-specialists. 001467774 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed May 16, 2023). 001467774 650_0 $$aIntestines$$xMicrobiology. 001467774 650_0 $$aIntestines$$xMetabolism. 001467774 655_0 $$aElectronic books. 001467774 77608 $$iPrint version:$$aBlachier, François$$tMetabolism of Alimentary Compounds by the Intestinal Microbiota and Health$$dCham : Springer International Publishing AG,c2023$$z9783031263217 001467774 852__ $$bebk 001467774 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-031-26322-4$$zOnline Access$$91397441.1 001467774 909CO $$ooai:library.usi.edu:1467774$$pGLOBAL_SET 001467774 980__ $$aBIB 001467774 980__ $$aEBOOK 001467774 982__ $$aEbook 001467774 983__ $$aOnline 001467774 994__ $$a92$$bISE