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Intro
Introduction
Contents
Contributors
Part I: Behavioral Health
Chapter 1: Treatment Strategies in ADD-1999
Background
Objective
Design and Methods
Results
Importance
Updates
Bottom Line
References
Chapter 2: Cognitive Behavioral Therapy Versus Medications in Depression-2005
Background
Objective
Design and Methods
Results
Importance
Updates
Bottom Line
References
Chapter 3: Treatment for Major Depressive Disorder (STAR*D)-2008
Background
Objective
Design and Methods
Results
Importance
Updates

Bottom Line
References
Chapter 4: Depression Screening Questions-2017
Background
Objective
Design and Methods
Results
Importance
Bottom Line
References
Part II: Cardiovascular Disease
Chapter 5: Pre-operative Clearance (Goldman Criteria)-1977
Background
Objective
Design and Methods
Results
Importance
Updates
Bottom Line
References
Chapter 6: Thrombolysis in Acute Strokes (ECASS-II)-1998
Background
Objective
Design and Methods
Results
Importance
Updates
Bottom Line
References

Chapter 7: Rate Versus Rhythm Control in Atrial Fibrillation (AFFIRM)-2002
Background
Objective
Design and Methods
Results
Importance
Updates
Bottom Line
References
Chapter 8: Defibrillators in Low-Ejection Fraction Patients (MADIT-II)-2002
Background
Objective
Design and Methods
Results
Importance
Updates
Bottom Line
References
Chapter 9: Medical Versus Interventional Management of Stable CAD (COURAGE)-2007
Background
Objective
Design and Methods
Results
Update
Importance
Bottom Line
References

Chapter 10: Dabigatran Versus Warfarin in Atrial Fibrillation (RE-LY)-2009
Background
Objective
Design and Methods
Results
Importance
Updates
Bottom Line
References
Chapter 11: Aspirin and Clopidogrel in Transient Ischemic Attacks (CHANCE)-2013
Background
Objective
Design and Methods
Results
Importance
Updates
Bottom Line
References
Chapter 12: Aspirin and Clopidogrel in High-Risk Transient Ischemic Attacks (POINT)-2018
Background
Objective
Designs and Methods
Results
Importance
Updates
Bottom Line
References

Chapter 13: Dapagliflozin in Low-EF Congestive Heart Failure (DAPA-HF)-2019
Background
Objective
Design and Methods
Results
Importance
Updates
Bottom Line
References
Chapter 14: Early Rhythm Control in Atrial Fibrillation (EAST)2020
Background
Objective
Design and Methods
Results
Importance
Updates
Bottom Line
References
Chapter 15: Empagliflozin in Diastolic Heart Failure (EMPEROR)-2021
Background
Objective
Design and Methods
Results
Importance
Updates
Bottom Line
References
Part III: Diabetes

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