001468385 000__ 04118cam\\22006137i\4500
001468385 001__ 1468385
001468385 003__ OCoLC
001468385 005__ 20230707003249.0
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001468385 008__ 230601s2023\\\\sz\a\\\\ob\\\\001\0\eng\d
001468385 019__ $$a1380745138
001468385 020__ $$a9783031295416$$q(electronic bk.)
001468385 020__ $$a3031295412$$q(electronic bk.)
001468385 020__ $$z9783031295409
001468385 020__ $$z3031295404
001468385 0247_ $$a10.1007/978-3-031-29541-6$$2doi
001468385 035__ $$aSP(OCoLC)1380875404
001468385 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dYDX$$dEBLCP
001468385 049__ $$aISEA
001468385 050_4 $$aRM301.5
001468385 08204 $$a615.7$$223/eng/20230601
001468385 24500 $$aAdvances in pharmacokinetics and pharmacodynamics /$$cPanos Macheras, editor.
001468385 264_1 $$aCham :$$bSpringer,$$c2023.
001468385 300__ $$a1 online resource (xi, 204 pages) :$$billustrations (some color)
001468385 336__ $$atext$$btxt$$2rdacontent
001468385 337__ $$acomputer$$bc$$2rdamedia
001468385 338__ $$aonline resource$$bcr$$2rdacarrier
001468385 4901_ $$aAAPS introductions in the pharmaceutical sciences,$$x2522-8358 ;$$vvolume 9
001468385 504__ $$aIncludes bibliographical references and index.
001468385 5050_ $$aPharmacokinetics -- Chapter 1: Current status in PBPK modeling -- Chapter 2: Physiologically based biopharmaceutics modeling (PBBM) Application on Food Effect Assessment -- Chapter 3: Physiologically based finite time pharmacokinetic (PBFTPK) models: Inception and development -- Chapter 4: Physiologically based finite time pharmacokinetic (PBFTPK) models: Applications -- Pharmacodynamics -- Chapter 5: Pharmacokinetic – Pharmacodynamic Modelling and Simulation in Clinical Practice and Studies -- Chapter 6: On the Verge of Impossibility: Accounting for Variability Arising from Permutations of Comorbidities that Affect the Fate of Drugs in the Human Body -- Chapter 7: Impact of Clinical Pharmacology on the Modernization of Drug Development and Regulation.
001468385 506__ $$aAccess limited to authorized users.
001468385 520__ $$aThis book provides a concise overview of recent advances in Pharmacokinetics (PK) and Pharmacodynamics (PD). The pharmacokinetics section covers the state of the art in Physiologically Based Pharmacokinetic (PBPK) modeling (Chapter 1) as well as the assessment of food effect on drug absorption using PBPK modeling (Chapter 2). Chapters 3 and 4 describe the recent development of Physiologically Based Finite Time Pharmacokinetic (PBFTPK) models and their applications to pharmacokinetic data. The pharmacodynamics section focuses on PK/PD modeling. Chapter 5 provides an overview of PK/PD modeling and simulation in clinical practice and studies. Chapter 6 deals with the subject/physiology variability issue encountered in PK/PD studies, while Chapter 7 reviews the influence of clinical pharmacology in the modernization of drug development and regulation. This book is an essential reference for pharmaceutical scientists.
001468385 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed June 1, 2023).
001468385 650_0 $$aPharmacokinetics.
001468385 650_0 $$aDrugs$$xPhysiological effect.
001468385 655_0 $$aElectronic books.
001468385 7001_ $$aMacheras, P.$$q(Panos),$$eeditor.$$1https://orcid.org/0000-0003-2375-0552
001468385 77608 $$iPrint version: $$z3031295404$$z9783031295409$$w(OCoLC)1371400337
001468385 830_0 $$aAAPS introductions in the pharmaceutical sciences ;$$vv. 9.$$x2522-8358
001468385 852__ $$bebk
001468385 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-031-29541-6$$zOnline Access$$91397441.1
001468385 909CO $$ooai:library.usi.edu:1468385$$pGLOBAL_SET
001468385 980__ $$aBIB
001468385 980__ $$aEBOOK
001468385 982__ $$aEbook
001468385 983__ $$aOnline
001468385 994__ $$a92$$bISE