2.3 Research Applications of PET Imaging in Neuroscience
2.3.1 Dementia
2.3.1.1 18F-FDG PET
2.3.1.2 A[beta] PET
2.3.1.3 Tau PET
2.3.2 Movement Disorders
2.3.2.1 Dopaminergic Imaging
2.3.2.2 18F-FDG PET
2.3.2.3 Molecular Pathology Imaging
2.3.3 Epilepsy
2.3.3.1 18F-FDG PET
2.3.3.2 Neuroreceptor Imaging
2.3.3.3 Other PET Imaging Methods
Suggested Readings
3: Research Applications of Functional Magnetic Resonance Imaging (fMRI) in Neuroscience
3.1 Principles of Blood Oxygen Level-Dependent (BOLD) Imaging

Intro
Preface
Preface
Contents
About the Editors
1: Introduction to Positron Emission Tomography/Magnetic Resonance (PET/MR) Imaging
1.1 History of PET/MR
1.2 PET/MR Equipment
1.2.1 Components of the Integrated PET/MR System
1.2.2 Hardware Compatibility
1.2.3 Principles of PET/MR Imaging
1.2.3.1 Principles of PET Imaging
1.2.3.2 Principles of MR Imaging
1.2.3.3 Attenuation Correction Technology
1.3 PET/MR Scan Protocols
1.3.1 Pre-Scan Preparation
1.3.2 PET/MR Data Acquisition

1.3.2.1 Scanning Coils and Body Positions for Integrated PET/ MR
1.3.2.2 PET Scan Parameters
1.3.2.3 MRI Scan Parameters
Suggested Readings
2: Research Applications of PET Imaging in Neuroscience
2.1 Principles of PET Imaging
2.1.1 Physical Principles of PET Imaging
2.1.2 PET Scanning System
2.1.2.1 Gantry
Detector
Scintillation Detectors
Semiconductor Detectors
2.1.3 PET Image Acquisition
2.1.3.1 Emission Scanning
2D and 3D Acquisition
Static and Dynamic Acquisition
Gated Acquisition
Local and Whole-Body Acquisition

2.1.3.2 Transmission Scanning
2.1.4 PET Image Reconstruction
2.1.4.1 Analytical Methods
2.1.4.2 Iterative Methods
2.1.4.3 Deep Learning Algorithms
2.1.5 Data Correction
2.1.5.1 Detector Normalization
2.1.5.2 Radionuclide Decay Correction
2.1.5.3 Tissue Attenuation Correction
2.1.5.4 Random Coincidence Correction
2.1.5.5 Scatter Correction
2.1.5.6 Dead-Time Correction
2.1.6 Performance Evaluation of PET Systems
2.1.6.1 Energy Resolution
2.1.6.2 Spatial Resolution
2.1.6.3 Temporal Resolution
2.1.6.4 Noise Equivalent Count Rate

2.1.6.5 System Sensitivity
2.1.6.6 Maximum Count Rate
2.2 Post-processing of PET Data
2.2.1 Image Pre-Processing
2.2.1.1 Head Motion Correction
2.2.1.2 Registration
2.2.1.3 Partial Volume Correction
MG Method
ROI-Based PVC
2.2.1.4 Spatial Normalization
2.2.1.5 Smoothing
2.2.2 Quantitative Analysis
2.2.2.1 Absolute Quantitative Analysis
2.2.2.2 Semi-Quantitative Analysis
2.2.3 SPM
2.2.4 Other Methods of Image Analysis
2.2.4.1 Spatial Covariance Analysis
2.2.4.2 Metabolic Brain Network Analysis