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Table of Contents
Intro
Contents
Editors Biography
Part I Clinical Applications
Medical Photon-Counting CT: Status and Clinical ApplicationsReview
1 Introduction
2 Principles of Medical Photon-Counting CT
2.1 Properties of Solid-State Scintillation Detectors
2.2 Properties of Photon-Counting Detectors
2.3 Challenges for Photon-Counting Detectors in Medical CT
3 Pre-clinical Evaluation of Photon-Counting CT
References
Coronary Artery Calcifications Assessment with Photon-counting Detector Computed Tomography
1 Introduction
2 The Agatston Score (AS) for CAC Scoring
2.1 Definition of the Agatston Score
2.2 Phantom Inserts for AS Performance Assessment
2.3 Impact of the Blooming Artifact
3 Comparison of EID-CT and PCD-CT for Calcium Scoring
3.1 Agatston Score Values
3.2 Noise Reduction
3.3 Resolution Increase
3.4 Dose Robustness
3.5 Discussion and Limits
3.6 Clinical Implications
4 Spectral Information for Calcium Scoring
4.1 Virtual Monoenergetic Images (VMIs)
4.2 Material Classification
5 Conclusion
References
MARS for Orthopaedic Pathology
1 Introduction
2 Background
2.1 Conventional Imaging Modalities for Orthopaedic Applications
2.2 Spectral Photon-Counting CT with the MARS Imaging System
3 Applications of MARS Spectral Photon-Counting CT
3.1 Acute Fractures
3.2 Evaluation of Fracture Healing
3.3 Bone-Metal Interface Imaging
3.4 Bone Marrow Oedema Measurements
3.5 Bone Quality Measures: Bone Structure and Material Maps
4 Summary
References
MARS for Molecular Imaging and Preclinical Studies
1 Introduction
2 Background
3 Molecular Imaging Applications
3.1 Infectious Disease: Pulmonary Tuberculosis
3.2 Cancer
3.3 Characterization of Atherosclerotic Plaque
3.4 Bone Health
3.5 Cartilage Health
3.6 Crystal-Induced Arthropathies
4 Summary
References
Quantitative Breast Lesion Characterization with Spectral Mammography: A Feasibility Study
1 Introduction
2 Materials and Methods
2.1 Spectral Mammography System
2.2 Dual-Energy Calibration
2.3 Phantom and Tissue Validation
2.4 Image Processing
3 Results
4 Discussions
5 Conclusions
References
Quantitative Breast Imaging with Low-Dose Spectral Mammography
1 Introduction
2 Theory
2.1 Theoretical Conversion
2.2 Experimental Conversion
3 Dual-Energy Material Decomposition Using Spectral Mammography: A Simulation Study
4 Dual-Energy Breast Density Quantification Using Spectral Mammography: A Phantom Study
4.1 Spectral Mammography System
4.2 Tissue-Equivalent Phantoms
4.3 Results
5 Quantification of Water and Lipid Density with Dual-Energy Mammography: Validation in Postmortem Breasts
5.1 Image Acquisition and Processing
5.2 Chemical Analysis
5.3 Results
5.4 Discussions
6 Conclusions
References
Contents
Editors Biography
Part I Clinical Applications
Medical Photon-Counting CT: Status and Clinical ApplicationsReview
1 Introduction
2 Principles of Medical Photon-Counting CT
2.1 Properties of Solid-State Scintillation Detectors
2.2 Properties of Photon-Counting Detectors
2.3 Challenges for Photon-Counting Detectors in Medical CT
3 Pre-clinical Evaluation of Photon-Counting CT
References
Coronary Artery Calcifications Assessment with Photon-counting Detector Computed Tomography
1 Introduction
2 The Agatston Score (AS) for CAC Scoring
2.1 Definition of the Agatston Score
2.2 Phantom Inserts for AS Performance Assessment
2.3 Impact of the Blooming Artifact
3 Comparison of EID-CT and PCD-CT for Calcium Scoring
3.1 Agatston Score Values
3.2 Noise Reduction
3.3 Resolution Increase
3.4 Dose Robustness
3.5 Discussion and Limits
3.6 Clinical Implications
4 Spectral Information for Calcium Scoring
4.1 Virtual Monoenergetic Images (VMIs)
4.2 Material Classification
5 Conclusion
References
MARS for Orthopaedic Pathology
1 Introduction
2 Background
2.1 Conventional Imaging Modalities for Orthopaedic Applications
2.2 Spectral Photon-Counting CT with the MARS Imaging System
3 Applications of MARS Spectral Photon-Counting CT
3.1 Acute Fractures
3.2 Evaluation of Fracture Healing
3.3 Bone-Metal Interface Imaging
3.4 Bone Marrow Oedema Measurements
3.5 Bone Quality Measures: Bone Structure and Material Maps
4 Summary
References
MARS for Molecular Imaging and Preclinical Studies
1 Introduction
2 Background
3 Molecular Imaging Applications
3.1 Infectious Disease: Pulmonary Tuberculosis
3.2 Cancer
3.3 Characterization of Atherosclerotic Plaque
3.4 Bone Health
3.5 Cartilage Health
3.6 Crystal-Induced Arthropathies
4 Summary
References
Quantitative Breast Lesion Characterization with Spectral Mammography: A Feasibility Study
1 Introduction
2 Materials and Methods
2.1 Spectral Mammography System
2.2 Dual-Energy Calibration
2.3 Phantom and Tissue Validation
2.4 Image Processing
3 Results
4 Discussions
5 Conclusions
References
Quantitative Breast Imaging with Low-Dose Spectral Mammography
1 Introduction
2 Theory
2.1 Theoretical Conversion
2.2 Experimental Conversion
3 Dual-Energy Material Decomposition Using Spectral Mammography: A Simulation Study
4 Dual-Energy Breast Density Quantification Using Spectral Mammography: A Phantom Study
4.1 Spectral Mammography System
4.2 Tissue-Equivalent Phantoms
4.3 Results
5 Quantification of Water and Lipid Density with Dual-Energy Mammography: Validation in Postmortem Breasts
5.1 Image Acquisition and Processing
5.2 Chemical Analysis
5.3 Results
5.4 Discussions
6 Conclusions
References