001468585 000__ 06009cam\\22006137i\4500 001468585 001__ 1468585 001468585 003__ OCoLC 001468585 005__ 20230707003258.0 001468585 006__ m\\\\\o\\d\\\\\\\\ 001468585 007__ cr\un\nnnunnun 001468585 008__ 230612s2023\\\\sz\a\\\\ob\\\\000\0\eng\d 001468585 019__ $$a1380745214$$a1381096600 001468585 020__ $$a9783031316326$$q(electronic bk.) 001468585 020__ $$a3031316320$$q(electronic bk.) 001468585 020__ $$z9783031316319 001468585 020__ $$z3031316312 001468585 0247_ $$a10.1007/978-3-031-31632-6$$2doi 001468585 035__ $$aSP(OCoLC)1381871183 001468585 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dYDX$$dEBLCP 001468585 049__ $$aISEA 001468585 050_4 $$aR853.S7 001468585 08204 $$a610.727$$223/eng/20230612 001468585 1001_ $$aCleophas, Ton J. M.,$$eauthor. 001468585 24510 $$aModern survival analysis in clinical research :$$bCox regressions versus accelerated failure time models /$$cTon J. Cleophas, Aeilko H. Zwinderman. 001468585 264_1 $$aCham :$$bSpringer,$$c2023. 001468585 300__ $$a1 online resource (xiv, 224 pages) :$$billustrations 001468585 336__ $$atext$$btxt$$2rdacontent 001468585 337__ $$acomputer$$bc$$2rdamedia 001468585 338__ $$aonline resource$$bcr$$2rdacarrier 001468585 504__ $$aIncludes bibliographical references. 001468585 5050_ $$aPreface -- Chapter 1: Regression Analysis -- Chapter 2: Cox Regressions -- Chapter 3: Accelerated Failure Time Models -- Chapter 4: Simple Dataset with Event as Outcome and Treatment as Predictor -- Chapter 5: Simple Dataset with Death as Outcome and Treatment Modality, Cholesterol, and Age as Predictors -- Chapter 6: Glioma Brain Cancer -- Chapter 7: Linoleic Acid for Colonic Carcinoma -- Chapter 8: The Effect on Survival of Maintained Chemotherapy with Acute Myelogenous Leucemia -- Chapter 9: Eighty Four Month Parallel Group Mortality Study -- Chapter 10: The Effect on Survival from Stages 1 and 2 Histiocytic Lymphoma -- Chapter 11: Survival of 64 Lymphoma Patients with or without B Symptoms -- Chapter 12: Effect on Time-to-Event of Group Membership -- Chapter 13: The Effect on Survival of Group Membership -- Chapter 14: Deaths from Carcinoma after Exposure to Carcinogens in Rats -- Chapter 15: Effect of Group Membership on Survival -- Chapter 16: Multiple Variables Regression Study of 2421 Stroke Patients Assessed for Time to Second Stroke -- Chapter 17: Hypothesized 55 Patient Study of Effect of Treatment Modality on Survival -- Chapter 18: One Year Follow-up Study with Many Censored Patients -- Chapter 19: Alcohol Relapse after Detox Program Treated with or without Personal Coach -- Chapter 20: Alcohol Relapse after Detox Program with 3 Predictors -- Chapter 21: Ayurvedic Therapy for Human Immunodeficiency Virus -- Chapter 22: Time to Event other Than Cox -- Chapter 23: Abstracts of the Chapters 1 to 22. 001468585 506__ $$aAccess limited to authorized users. 001468585 520__ $$aAn important novel menu for Survival Analysis entitled Accelerated Failure Time (AFT) models has been published by IBM (international Businesss Machines) in its SPSS statistical software update of 2023. Unlike the traditional Cox regressions that work with hazards, which are the ratio of deaths and non-deaths in a sample, it works with risk of death, which is the proportion of deaths in the same sample. The latter approach may provide better sensitivity of testing, but has been seldom applied, because with computers risks are tricky and hazards because they are odds are fine. This was underscored in 1997 by Keiding and colleague statisticians from Copenhagen University who showed better-sensitive goodness of fit and null-hypothesis tests with AFT than with Cox survival tests. So far, a controlled study of a representative sample of clinical Kaplan Meier assessments, where the sensitivity of Cox regression is systematically tested against that of AFT modeling, has not been accomplished. This edition is the first textbook and tutorial of AFT modeling both for medical and healthcare students and for professionals. Each chapter can be studied as a standalone, and, using, real as well as hypothesized data, it tests the performance of the novel methodology against traditional Cox regressions. Step by step analyses of over 20 data files stored at Supplementary Files at Springer Interlink are included for self-assessment. We should add that the authors are well qualified in their field. Professor Zwinderman is past-president of the International Society of Biostatistics (2012-2015) and Professor Cleophas is past-president of the American College of Angiology (2000-2002). From their expertise they should be able to make adequate selections of modern data analysis methods for the benefit of physicians, students, and investigators. The authors have been working and publishing together for 25 years and their research can be characterized as a continued effort to demonstrate that clinical data analysis is not mathematics but rather a discipline at the interface of biology and mathematics. 001468585 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed June 12, 2023). 001468585 650_0 $$aSurvival analysis (Biometry) 001468585 650_0 $$aFailure time data analysis. 001468585 650_0 $$aRegression analysis. 001468585 655_0 $$aElectronic books. 001468585 7001_ $$aZwinderman, Aeilko H.,$$eauthor. 001468585 77608 $$iPrint version: $$z3031316312$$z9783031316319$$w(OCoLC)1374113172 001468585 852__ $$bebk 001468585 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-031-31632-6$$zOnline Access$$91397441.1 001468585 909CO $$ooai:library.usi.edu:1468585$$pGLOBAL_SET 001468585 980__ $$aBIB 001468585 980__ $$aEBOOK 001468585 982__ $$aEbook 001468585 983__ $$aOnline 001468585 994__ $$a92$$bISE