001469618 000__ 04244nam\\2200601\i\4500 001469618 001__ 1469618 001469618 003__ OCoLC 001469618 005__ 20230803003339.0 001469618 006__ m\\\\\o\\d\\\\\\\\ 001469618 007__ cr\cn\nnnunnun 001469618 008__ 230613s2023\\\\sz\a\\\\ob\\\\000\0\eng\d 001469618 020__ $$a9783031069208$$q(electronic bk.) 001469618 020__ $$a303106920X$$q(electronic bk.) 001469618 020__ $$z9783031069192 001469618 020__ $$z3031069196 001469618 0247_ $$a10.1007/978-3-031-06920-8$$2doi 001469618 035__ $$aSP(OCoLC)1382339285 001469618 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE 001469618 049__ $$aISEA 001469618 050_4 $$aRD123 001469618 08204 $$a617.4/710592$$223/eng/20230613 001469618 1001_ $$aRosenberg, Nahum,$$eauthor. 001469618 24510 $$aAutologous bone grafting and regeneration :$$bclinical applications of biophysical osteoblast stimulation /$$cNahum Rosenberg. 001469618 264_1 $$aCham :$$bSpringer,$$c[2023] 001469618 264_4 $$c©2023 001469618 300__ $$a1 online resource (xv, 76 pages) :$$billustrations (some color) 001469618 336__ $$atext$$btxt$$2rdacontent 001469618 337__ $$acomputer$$bc$$2rdamedia 001469618 338__ $$aonline resource$$bcr$$2rdacarrier 001469618 504__ $$aIncludes bibliographical references. 001469618 5050_ $$a1 Theoretical framework supporting the research of biophysical stimulation of osteoblasts -- 2. Methodologies used and their rationale -- 3. Osteoblast explant cultures -- 4. End parameters -- 5. Determination of in vitro generated tissue -- 6. In vitro safety studies -- 7. In vivo safety evaluation -- 8. Efficacy in vivo studies -- 9. Setups for external application of biophysical energy -- 10. Mechanical stimulation -- 11. The original contribution to knowledge -- 12. Contribution to developing the theory in the field -- 13. The impact of the work on professional practice -- 14. The nature of the works academic impact -- 15. The strengths and weaknesses of the methodologies used (critical analysis) -- 16. Conclusion. 001469618 506__ $$aAccess limited to authorized users. 001469618 520__ $$aThis book integrates the current basic and clinical knowledge in the area of biophysical stimulation of osteoblast for in vitro and in vivo live bone generation. This innovative methodology and its applications are presented and discussed in several clinical conditions: treatment of fracture nonunion, spine stabilization, bone replacement after tumor resections, stabilization of failed joint endoprostheses in revision surgery and in treatment of bone loss (osteoporosis and osteopenia). The author analyses different types of biophysical stimulation of osteoblasts for bone regeneration, e.g. mechanical (static and alternating, including distraction osteogenesis), electromagnetic (pulsed, alternating, static), light (at different spectrum range, including laser), acoustic (including ultrasound), RF etc. Moreover, he summarizes and discusses the most significant findings for in vitro bone generation and its resulting clinical use as autologous bone graft without surgical morbidity. Reflecting the authors extensive experience this book is an excellent source of knowledge and a valuable aid to clinical practice for all orthopedic surgeons, fellows, and researchers wanting to gain insights into this promising field. . 001469618 588__ $$aDescription based on print version record. 001469618 650_0 $$aBone-grafting. 001469618 650_0 $$aBone regeneration. 001469618 650_0 $$aBone substitutes. 001469618 655_0 $$aElectronic books. 001469618 77608 $$iPrint version:$$aRosenberg, Nahum.$$tAutologous bone grafting and regeneration.$$dCham : Springer, 2022$$z9783031069192$$w(OCoLC)1338675445 001469618 852__ $$bebk 001469618 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-031-06920-8$$zOnline Access$$91397441.1 001469618 909CO $$ooai:library.usi.edu:1469618$$pGLOBAL_SET 001469618 980__ $$aBIB 001469618 980__ $$aEBOOK 001469618 982__ $$aEbook 001469618 983__ $$aOnline 001469618 994__ $$a92$$bISE