001469639 000__ 04145cam\\2200601\i\4500 001469639 001__ 1469639 001469639 003__ OCoLC 001469639 005__ 20230803003340.0 001469639 006__ m\\\\\o\\d\\\\\\\\ 001469639 007__ cr\cn\nnnunnun 001469639 008__ 230614s2023\\\\sz\a\\\\ob\\\\000\0\eng\d 001469639 020__ $$a9783031322761$$q(electronic bk.) 001469639 020__ $$a3031322762$$q(electronic bk.) 001469639 020__ $$z3031322754 001469639 020__ $$z9783031322754 001469639 0247_ $$a10.1007/978-3-031-32276-1$$2doi 001469639 035__ $$aSP(OCoLC)1382386963 001469639 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dEBLCP$$dOCLCF 001469639 049__ $$aISEA 001469639 050_4 $$aQP86 001469639 08204 $$a612.6/7$$223/eng/20230614 001469639 1001_ $$aNydegger, U. E.,$$eauthor. 001469639 24510 $$aSenescence back and forth /$$cUrs Nydegger, Thomas Lung. 001469639 264_1 $$aCham :$$bSpringer,$$c[2023] 001469639 264_4 $$c©2023 001469639 300__ $$a1 online resource (xxiii, 132 pages) :$$billustrations (chiefly color) 001469639 336__ $$atext$$btxt$$2rdacontent 001469639 337__ $$acomputer$$bc$$2rdamedia 001469639 338__ $$aonline resource$$bcr$$2rdacarrier 001469639 504__ $$aIncludes bibliographical references. 001469639 5050_ $$aSenescence opposed to longevity -- Genetics, the language of Proteomics -- Plants Uncover Senescence Animals Way Off Humans -- Rejuvenation stops Senescence -- Overlap of Senescence with Disease -- Mosaic Restricted to the Individuum -- Remaining Time until Death -- Laboratory Checkups -- eroprotectors. 001469639 506__ $$aAccess limited to authorized users. 001469639 520__ $$aThis book is about lifelong ageing of humans. The basic biochemical and genetic mechanisms remain ill known, and differ among individuals. The book starts out to explore the plant and animal kingdoms to answer questions human ageing needs for understanding. First, we come to scrutinize time running out and what normal means with impacts on the genome and on protein half- lives and function. Ageing goes beyond biochemical skid treated by geroprotector drugs, including biosimilars; albeit early diagnosis with standard medical laboratory assays, here addressed, sheds light with focus on basic research. Modern tools, including machine learning, and DNA technology, e.g. genomics, have already provided for unanticipated insights. The chapters then turn around senescence of the entire organism based on variable ageing of single organs embedded in neuronal networks . Psychological stress factors, dementia opposed to vigilance, and distinction of ageing from overt disease are contrasting in humans and are opposed in the book. Senescence, seen as a one way track may be reverted into rejuvenation, made possible by insights into immunosenescence and genomic approaches. Risk management in health insurance finds important clues in this book. The topics addressed between the book covers help to understand the trend to the ever- prolonging life expectancy beyond the centenarian age group; nursing care takers and pharmaceutical industry are invited to understand what is going on in senior people to make their geriatric population remain fit or become frail. 001469639 588__ $$aDescription based on print version record. 001469639 650_0 $$aAging. 001469639 650_0 $$aAge factors in disease. 001469639 655_0 $$aElectronic books. 001469639 7001_ $$aLung, Thomas,$$eauthor. 001469639 77608 $$iPrint version:$$aNYDEGGER, URS. LUNG, THOMAS.$$tSENESCENCE BACK AND FORTH.$$d[Place of publication not identified] : SPRINGER INTERNATIONAL PU, 2023$$z3031322754$$w(OCoLC)1374816275 001469639 852__ $$bebk 001469639 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-031-32276-1$$zOnline Access$$91397441.1 001469639 909CO $$ooai:library.usi.edu:1469639$$pGLOBAL_SET 001469639 980__ $$aBIB 001469639 980__ $$aEBOOK 001469639 982__ $$aEbook 001469639 983__ $$aOnline 001469639 994__ $$a92$$bISE