Intro
Foreword
Preface
Contents
Contributors
Chapter 1: WHO Critical Priority Escherichia coli in Latin America: A One Health Challenge for a Post-Pandemic World
1.1 Introduction
1.1.1 Critical Priority E. coli in Brazil
1.1.2 Critical Priority E. coli in Argentina
1.1.3 Critical Priority E. coli in Uruguay
1.1.4 Critical Priority E. coli in Chile
1.1.5 Critical Priority E. coli in Ecuador
1.1.6 Critical Priority E. coli in Bolivia
1.1.7 Critical Priority E. coli in Peru
1.2 Conclusions
References
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Chapter 2: Recent Progress on Enterotoxigenic E. coli (ETEC) and Antibiotic Resistance in Pathogenic E. coli
2.1 General Concepts About ETEC
2.1.1 ETEC Is a Major Human Pathogen
2.1.2 ETEC Can Be a Food and Waterborne Pathogen
2.1.3 Animal ETEC
2.2 Recent Discoveries in Virulence and Pathogenesis
2.3 Epidemiology of ETEC in Latin America
2.4 Deciphering ETEC Evolution and Dissemination Through Genomics
2.5 The Microbiome and ETEC
2.6 ETEC Vaccines
2.7 Updates on Antibiotic Resistance in Intestinal and Extraintestinal E. coli

2.7.1 Antibiotic Resistance in Diarrheagenic E. coli (DEC)
2.7.2 Antibiotic Resistance in Extraintestinal E. coli (ExPEC)
References
Chapter 3: New Concepts on Domestic and Wild Reservoirs and Transmission of E. coli and Its Environment
3.1 Introduction
3.2 Animal Reservoirs of Several Pathotypes Described in the Last Years
3.2.1 Small Ruminants
3.2.2 Other Ungulates
3.2.3 Pets
3.2.4 Birds
3.2.5 Rodents
3.2.6 Other Reports from Wild Animals
3.3 E. coli Outside the Host
3.3.1 E. coli in the Aquatic Environment: Fecal Source or Adaptation?

3.3.2 E. coli in Soil
3.3.3 E. coli in the Soil of Urban Areas
3.3.4 STEC in the Environment of Farm
3.4 E. coli as a Source of Antimicrobial Resistance
3.4.1 Antimicrobial Resistance Crisis and Commensal E. coli
3.4.2 AMR in the Environment
3.4.3 AMR in the Food
3.4.4 Directionality of Domestic Animals and Humans
References
Chapter 4: New Molecular Mechanisms of Virulence and Pathogenesis in E. coli
4.1 Introduction
4.2 The Type III Secretion System (T3SS) in E. coli
4.2.1 Architecture of the Type III Secretion System

4.2.2 Hierarchical Substrate Secretion: Molecular Switches
4.3 Type III Secretion System as Targets of Anti-virulence Agents for Pathogenic E. coli
4.4 Role of the Type VI Secretion System (T6SS) in E. coli
4.4.1 Structure of the T6SS
4.4.2 E. coli T6SS Effectors
4.5 Virulence Response of Pathogenic E. coli to the Microbiota
4.5.1 Regulation of E. coli Virulence Factors by the Microbiota
4.5.2 Modulation of E. coli Pathogenesis by Bacterial Proteases
4.5.3 Interbacterial Competition Using the T6SS