001471871 000__ 04397cam\\22006017i\4500 001471871 001__ 1471871 001471871 003__ OCoLC 001471871 005__ 20230908003319.0 001471871 006__ m\\\\\o\\d\\\\\\\\ 001471871 007__ cr\un\nnnunnun 001471871 008__ 230719s2023\\\\sz\a\\\\o\\\\\001\0\eng\d 001471871 020__ $$a9783031269455$$q(electronic bk.) 001471871 020__ $$a3031269454$$q(electronic bk.) 001471871 020__ $$z9783031269448 001471871 0247_ $$a10.1007/978-3-031-26945-5$$2doi 001471871 035__ $$aSP(OCoLC)1390750138 001471871 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dEBLCP$$dOCLCQ 001471871 049__ $$aISEA 001471871 050_4 $$aQP801.P8 001471871 08204 $$a547/.596$$223/eng/20230719 001471871 24500 $$aPurinergic signaling in neurodevelopment, neuroinflammation and neurodegeneration /$$cHenning Ulrich, Peter Illes, Talita Glaser, editors. 001471871 264_1 $$aCham :$$bSpringer,$$c2023. 001471871 300__ $$a1 online resource (x, 376 pages) :$$billustrations (some color) 001471871 336__ $$atext$$btxt$$2rdacontent 001471871 337__ $$acomputer$$bc$$2rdamedia 001471871 338__ $$aonline resource$$bcr$$2rdacarrier 001471871 500__ $$aIncludes index. 001471871 5050_ $$aThe Purinergic Signaling: Overview -- Adenosine A2A Receptor-containing Heteromers and Neuroprotection -- Purinergic Signaling in Brain Physiology -- Neurotrophic Actions of Adenosine and Guanosine: Implications for Neural Development and Regeneration? -- Purinergic Signaling in Neurogenesis and Neural Fate Determination: Current Knowledge and Future Challenges -- Purinergic Signaling in Autism Spectrum Disorder -- Purinergic Signaling in Depression -- Roles of Purinergic Receptors in Alzheimer's Disease -- Purinergic Signaling in Basal Ganglia Diseases: Parkinson's Disease -- A Step in the ALS Direction: Lessons from the Purinome -- Purinergic P2 Receptors in Epilepsy -- Purinergic Signaling in Neuroinflammation -- Purinergic Signaling in Brain Tumors -- Development of Purinergic Receptor Agonists and Antagonists -- Acupuncture for Counteracting P2X4 and P2X7 Receptor Involvement in Neuroinflammation. 001471871 506__ $$aAccess limited to authorized users. 001471871 520__ $$aThis volume explores the quickly evolving field of Purinergic signaling, and examines how receptors for ATP and other nucleotides, and receptors for adenosine, act in neuronal transmission, control of synaptic activity, proliferation, differentiation and cell death regulation in the CNS. This book focuses on the participation of purinergic receptors and ectonucleotidases, degrading ATP into adenosine, in embryonic and adult neurogenesis in vitro and in vivo as well as in synaptic transmission and pathophysiology. Further, the chapters discuss varying brain diseases, including Parkinson's, and Alzheimer's disease, autism, mood disorders and epilepsy, as well as brain tumors, in the context of purinergic signaling and its clinical aspects. The development of purinergic receptor agonists is also an important issue of this book. This book provides a critical review of the current state of science and will be useful for both scientists and students who are or would like to get involved in this area. Furthermore, this book addresses neuroscientists, physician and professionals from the industry, who would like to update themselves in this exciting and rapidly growing field of neuroscience. 001471871 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed July 19, 2023). 001471871 650_0 $$aPurines$$xReceptors. 001471871 650_0 $$aPurine nucleotides. 001471871 650_0 $$aPurine nucleosides. 001471871 650_0 $$aNervous system$$xDegeneration$$xMolecular aspects. 001471871 655_0 $$aElectronic books. 001471871 7001_ $$aUlrich, Henning,$$eeditor. 001471871 7001_ $$aIlles, Peter,$$eeditor. 001471871 7001_ $$aGlaser, Talita,$$eeditor. 001471871 852__ $$bebk 001471871 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-031-26945-5$$zOnline Access$$91397441.1 001471871 909CO $$ooai:library.usi.edu:1471871$$pGLOBAL_SET 001471871 980__ $$aBIB 001471871 980__ $$aEBOOK 001471871 982__ $$aEbook 001471871 983__ $$aOnline 001471871 994__ $$a92$$bISE