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001471918 001__ 1471918
001471918 003__ OCoLC
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001471918 019__ $$a1390915736
001471918 020__ $$a9783031325540$$q(electronic bk.)
001471918 020__ $$a3031325540$$q(electronic bk.)
001471918 020__ $$z3031325532
001471918 020__ $$z9783031325533
001471918 0247_ $$a10.1007/978-3-031-32554-0$$2doi
001471918 035__ $$aSP(OCoLC)1390918149
001471918 040__ $$aEBLCP$$beng$$cEBLCP$$dGW5XE$$dYDX$$dEBLCP$$dOCLCQ
001471918 049__ $$aISEA
001471918 050_4 $$aRG524
001471918 08204 $$a618.2
001471918 24500 $$aAdvances in maternal-fetal biomedicine :$$bcellular and molecular mechanisms of pregnancy pathologies /$$cMarcelo Gonzalez-Ortiz, editor.
001471918 260__ $$aCham :$$bSpringer,$$c2023.
001471918 300__ $$a1 online resource (314 p.).
001471918 4901_ $$aAdvances in Experimental Medicine and Biology ;$$vv. 1428
001471918 500__ $$a4.6 Interaction Between Folate, Vitamin B12, DHA, and Maternal Obesity
001471918 500__ $$aIncludes index.
001471918 5050_ $$aIntro -- About This Book -- Contents -- About the Editor -- 1: Feto-placental Unit: From Development to Function -- 1.1 Development of the Placenta -- 1.1.1 The Origin of Trophoblast -- 1.1.2 Lacunar Stage -- 1.1.3 Villous Stage -- 1.1.4 Cell Types of Human Placenta -- 1.1.4.1 Trophoblastic Cell Linage -- 1.1.4.2 Non-trophoblastic Cell Lineage -- 1.2 Placenta During the Final Embryonic Stage and the Fetal Period -- 1.2.1 Fetal Annexes -- 1.2.1.1 Umbilical Cord -- 1.2.1.2 Extraembryonic Membranes -- 1.2.2 Amniotic Fluid -- 1.2.2.1 Amniotic Fluid Pathologies
001471918 5058_ $$a1.2.3 Placental Pathologies -- 1.2.3.1 Abnormally Invasive Placenta -- 1.2.3.2 Gestational Trophoblastic Disease -- 1.2.3.3 Infectious Processes -- 1.3 Maternal-Fetal-Placental  Unit -- 1.3.1 Oxygen -- 1.3.2 Influence of Placental Architecture on Oxygen Transport -- 1.3.3 Oxygen-Induced Molecular Control of Placental Architecture/Performance -- 1.3.3.1 Hypoxia-Induced Factor (HIF) -- 1.3.3.2 HIF Is Necessary for Placental Development -- 1.3.3.3 HIF Controls the Placental Cell Fate -- 1.3.3.4 HIF Requirement for Angiogenesis in the Placenta -- 1.4 Placental Transport
001471918 5058_ $$a1.4.1 Endocytosis and Exocytosis -- 1.4.2 Channels -- 1.4.2.1 Transporters -- 1.5 Conclusion -- References -- 2: Role of Hormones During Gestation and Early Development: Pathways Involved in Developmental Programming -- 2.1 Introduction -- 2.2 Steroids -- 2.2.1 Androgens -- 2.2.2 Estrogens -- 2.2.3 Progesterone -- 2.3 Thyroid Hormones -- 2.4 Insulin-Like Growth Factors System -- 2.5 Developmental Programming -- 2.5.1 Androgens and Estrogens in Developmental Programming -- 2.5.1.1 PCOS as a Case -- 2.5.2 THs in Developmental Programming -- 2.5.3 IGFs and Developmental Programming
001471918 5058_ $$a2.5.4 Adipokines and Hormonal Regulation: Contribution of Adipose Tissue to Developmental Programming Effects -- 2.6 Epigenetic and Developmental Programming -- 2.6.1 Epigenetic Regulation During Gestation -- 2.6.2 Milk MicroRNAs in Lactation -- 2.7 Conclusions -- References -- 3: Physiological and Pathophysiological Role of Large-Conductance Calcium-Activated Potassium Channels (BKCa) in HUVECs and Placenta -- 3.1 Placental Function -- 3.2 Fetoplacental Circulation -- 3.3 Regulation of Placental Circulation by Potassium Channels -- 3.4 The Large Conductance Potassium Channels (BKCa)
001471918 5058_ $$a3.5 The Expression and Activity of BKCa in Human Umbilical Vein Endothelial Cells (HUVECs) -- 3.6 Potential Roles of BKCa in Placental Pathologies -- 3.7 Concluding Remarks -- References -- 4: Metabolic Interaction Between Folate, Vitamin B12, and Polyunsaturated Fatty Acids in Pregnancy -- 4.1 Introduction -- 4.2 Maternal and Fetal Folates and Vitamin B12 Requirements During Gestation -- 4.3 Biological Functions of Folate and Vitamin B12 -- 4.4 Folate and Vitamin B12 Imbalance During Pregnancy -- 4.5 DHA in Pregnancy and Biological Functions
001471918 506__ $$aAccess limited to authorized users.
001471918 520__ $$aThis textbook aims to describe physiological and pathophysiological mechanisms that underlie human maternal-fetal interactions. The book emphasizes the structure and development of the fetoplacental unit, the endocrine and nutritional regulation of fetal development, nitric oxide signalling, solute carriers function and ion channels regulation in healthy pregnancies and diseases, like preeclampsia, gestational diabetes, and maternal obesity, among others. Also, we highlight novel mechanisms associated with language impairment in children, the use of serotonin inhibitors or cannabis during pregnancy, and maternal conditions' potential impact on cerebrovascular development in newborns and infants. The cellular and molecular understanding of maternal-fetal physiology and pathophysiology will allow the readers to understand the impact of diseases or conditions that are highly prevalent in pregnant women.
001471918 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed July 26, 2023).
001471918 650_0 $$aObstetrics.
001471918 650_0 $$aBiomedical engineering.
001471918 655_0 $$aElectronic books.
001471918 7001_ $$aGonzalez-Ortiz, Marcelo.
001471918 77608 $$iPrint version:$$aGonzalez-Ortiz, Marcelo$$tAdvances in Maternal-Fetal Biomedicine$$dCham : Springer International Publishing AG,c2023$$z9783031325533
001471918 830_0 $$aAdvances in experimental medicine and biology ;$$vv. 1428.
001471918 852__ $$bebk
001471918 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-031-32554-0$$zOnline Access$$91397441.1
001471918 909CO $$ooai:library.usi.edu:1471918$$pGLOBAL_SET
001471918 980__ $$aBIB
001471918 980__ $$aEBOOK
001471918 982__ $$aEbook
001471918 983__ $$aOnline
001471918 994__ $$a92$$bISE