Plant-based therapeutics. Volume 1 : cannabis sativa / Ivan A. Ross.
Ross, Ivan A., author.
2023
RM666.C266
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Title
Plant-based therapeutics. Volume 1 : cannabis sativa / Ivan A. Ross.
Author
Ross, Ivan A., author.
ISBN
9783031351556
303135155X
DOI
https://doi.org/10.1007/978-3-031-35155-6
Publication Details
Cham, Switzerland : Springer, [2023]
Language
English
Description
1 online resource (670 p.)
Item Number
10.1007/978-3-031-35155-6 doi
Call Number
RM666.C266
Dewey Decimal Classification
615.7/827
Summary
By examining historical applications of the compounds found in plants, this five-volume series serves as a reference for quality assurance, research, product development, and regulatory guidance of the compounds found in plant-based medicines. This work supports the growing consumers' interest in herbal medicine for wellness and health. Plant-Based Therapeutics, Volume 1: Cannabis sativa, the first in the series, covers a unique plant species and provides the framework to integrate its evidence-based scientific discoveries with healthcare therapies. Cannabis has been used in religious ceremonies and medical purposes for thousands of years. Cannabidiol (CBD), the main non-psychoactive component of Cannabis, was isolated in the 1940s, and its structure was established in the 1960s. In 1964 tetrahydrocannabinol (THC), the psychoactive component, was isolated. Cannabis has more than 500 components, of which 104 cannabinoids have been identified. Two of them, THC and CBD, have been the primary components of scientific investigations. They were approved by the FDA for chemotherapy-induced nausea and vomiting in 1985; for appetite stimulation in wasting conditions, such as AIDS, in 1992, and in 2018 for treating two forms of pediatric epilepsy, Dravet syndrome and Lennox-Gastaut syndrome. Beyond the indications for which cannabinoids are FDA-approved, the evidence reveals that cannabinoid receptors are present throughout the body, embedded in cell membranes, and are believed to be more numerous than any other receptor system. When cannabinoid receptors are stimulated, a variety of physiologic processes ensue. Thus, other constituents of Cannabis are extremely promising either as individual compounds or their potential synergistic or entourage effects in the treatment of numerous medical conditions. .
Note
Description based upon print version of record.
Includes index.
Cannabis on Heart Rate and EEG
Access Note
Access limited to authorized users.
Available in Other Form
Plant-Based Therapeutics, Volume 1
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Intro
Contents
Abbreviations
Chapter 1: The History of Cannabis
Cannabis sativa L., fam. Cannabinaceae
Botanical Description
Origin and Distribution
Chapter 2: The Bioactive Components of Plants
Flavonoids
Proteins and Peptides
Glycosides
Alkaloids
Lignans
Resins
Saponins
References
Chapter 3: Chemical Constituents of Cannabis
Chemical Constituents
References
Chapter 4: The Bioactive Components of Cannabis
The Endocannabinoid System
The Entourage Effect of the Phytochemicals
Biosynthetic Pathways
Cannabinoid Receptors

Endocannabinoids in the Circulation
Endocannabinoids and Food
Endocannabinoids and Body Mass Index
Endocannabinoid and Circadian Rhythm
Endocannabinoids and Exercise
Endocannabinoids and Inflammation
The Endocannabinoids and Stress
Endocannabinoids and Chronic SNS or HPA Axis Activation
Endocannabinoids in Reward, Anxiety, and Cognition
Cannabinoids and Cognitive Functions
The Endocannabinoids and Pain
Terpenes
Phenols
Trichomes
Adverse Effects of Cannabinoids
References
Chapter 5: Neurological Effects of Cannabis

Factors Affecting the Impact of Cannabis Use on the Brain
Duration of Abstinence
Age of Onset of Cannabis Use
Frequency and Magnitude of Cannabis Use
Errors in Monitoring Awareness, Reward Processing, and Affective Processing
Functional MRI Studies on Cannabis
Endocannabinoid-Mediated LTP in Learning
The Homosynaptic and Heterosynaptic eCB-Mediated Potentiation
Memory and Cognitive Impairments
Cannabis on Attention and Working Memory
Cannabis and Spatial Working Memory
Cannabis and Executive Function
Neuropsychological Functioning in First-Episode Psychosis

Neurobiological Alterations During Pregnancy and Breastfeeding
Cannabis in Adolescence
Cannabis and Schizophrenia
Cannabis and Bipolar Disorder
Cannabis in Alzheimer's and Parkinson's Diseases
Cannabis and Alcohol Consumption
Cannabis and Tobacco Coadministration
Medical vs. Recreational Cannabis Use
Cannabis Flowers vs. Concentrate
Acute Administration of Delta-9-THC vs. CBD
Delta-9-THC vs. Delta-9-Tetrahydrocannabivarin
Delta-8-THC vs. Delta-9-THC
Drug Addiction
Cannabinoids and Pain
Cannabis and Gender Differences
Cannabis and HIV

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