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001476263 0247_ $$a10.1007/978-981-99-1443-2$$2doi
001476263 035__ $$aSP(OCoLC)1395184281
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001476263 049__ $$aISEA
001476263 050_4 $$aRC669
001476263 08204 $$a616.1$$223/eng/20230829
001476263 24500 $$aExtracellular vesicles in cardiovascular and metabolic diseases /$$cJunjie Xiao, editor.
001476263 260__ $$aSingapore :$$bSpringer,$$c2023.
001476263 300__ $$a1 online resource (viii, 275 pages).
001476263 336__ $$atext$$btxt$$2rdacontent
001476263 337__ $$acomputer$$bc$$2rdamedia
001476263 338__ $$aonline resource$$bcr$$2rdacarrier
001476263 4901_ $$aAdvances in Experimental Medicine and Biology Series ;$$vv.1418
001476263 500__ $$aDescription based upon print version of record.
001476263 5050_ $$aIntro -- Preface -- Contents -- Part I: Extraction Methods -- 1: Updated Methods of Extracellular Vesicles Isolation -- 1.1 Background -- 1.2 The Regular Methods of EVs Isolation -- 1.2.1 Ultracentrifugation (UC) -- 1.2.2 Density Gradient Centrifugation (DGC) -- 1.2.3 Size-Exclusion Chromatography (SEC) -- 1.2.4 Ultrafiltration (UF) -- 1.2.5 Immunoaffinity Capture (IAC) -- 1.2.6 Precipitation -- 1.3 Novel Method of EVs Extraction -- 1.3.1 Microfluidics-Based EVs Isolation Technique -- 1.3.2 Creative Combination of Different Methods -- 1.3.3 Newly Emerging Methods for EVs Isolation
001476263 5058_ $$a1.4 Recommended Methods for EVs Isolation from Biofluids -- 1.4.1 Plasma or Serum -- 1.4.2 Urine -- 1.4.3 Milk -- 1.4.4 Saliva -- 1.5 Recommended Protocols for EVs Extraction from Tissues -- 1.5.1 Brain -- 1.5.2 Intestinal Tissue -- 1.5.3 Muscles -- 1.5.4 Heart -- 1.6 Perspective -- References -- Part II: Extracellular Vesicles in Cardiovascular Disease -- 2: Extracellular Vesicles and Pathological Cardiac Hypertrophy -- 2.1 Background -- 2.2 Cardiomyocyte-Derived EVs on Pathological Cardiac Hypertrophy -- 2.3 Cardiac Fibroblast-Derived EVs on Pathological Cardiac Hypertrophy
001476263 5058_ $$a2.4 EVs from Other Cell Types in Pathological Cardiac Hypertrophy -- 2.5 Stem Cell-Derived Exosomes on Pathological Cardiac Hypertrophy -- 2.6 Exosomes from Cardiosphere-Derived Cells on Pathological Cardiac Hypertrophy -- 2.7 Translational Perspective -- 2.8 Conclusion -- References -- 3: Extracellular Vesicles and Cardiac Aging -- 3.1 Background -- 3.2 Accumulation of Cellular Injury and Cell Senescence -- 3.2.1 EVs, Aging, and Cell Senescence -- 3.3 Cardiac Aging and Cell Senescence -- 3.3.1 Cardiomyocytes -- 3.3.2 Fibroblasts -- 3.3.3 Endothelial Cells -- 3.3.4 Stem and Progenitor Cells
001476263 5058_ $$a3.4 Promising Approaches: Mitochondria-Enriched Vesicles -- 3.5 Perspectives -- References -- 4: Extracellular Vesicles and Ischemic Cardiovascular Diseases -- 4.1 Background -- 4.2 Different Sources of Extracellular Vesicles for Therapy of Ischemic Cardiovascular Diseases -- 4.3 Native Extracellular Vesicles for Ischemic Cardiovascular Therapeutics -- 4.4 Bioengineered Extracellular Vesicles for Ischemic Cardiovascular Therapeutics -- 4.5 EVs as Potential Biomarkers of Ischemic Cardiovascular Diseases -- 4.6 Conclusion and Future Perspectives -- References
001476263 5058_ $$a5: Extracellular Vesicles and Hypertension -- 5.1 Background -- 5.2 Extracellular Vesicles and Essential Hypertension -- 5.2.1 Roles of Extracellular Vesicles in Renin-Angiotensin-Aldosterone System -- 5.2.2 Roles of Extracellular Vesicles in Vascular Endothelial Cells -- 5.2.3 Roles of Extracellular Vesicles in Vascular Smooth Muscle Cells -- 5.2.4 Roles of Extracellular Vesicles in Vascular Fibroblasts -- 5.3 Extracellular Vesicles and Secondary Hypertension -- 5.3.1 Extracellular Vesicles and Acute Kidney Injury -- 5.3.2 Extracellular Vesicles and Renal Parenchymal Diseases
001476263 506__ $$aAccess limited to authorized users.
001476263 520__ $$aThis book provides the latest research progress on Extracellular vesicles (EVs) in cardiovascular and metabolic diseases. EVs are small bilayer lipid membrane vesicles released by cells and function for intercellular communication. Increasing evidence has shown that EVs play crucial roles in cardiovascular and metabolic diseases, which seriously threaten human health worldwide. The book contains four sections: 1) Extraction Methods; 2) EVs in Cardiovascular Diseases; 3) EVs in Metabolic Diseases; and 4) Therapeutic Implications. This book is useful for biologists, cardiologists, cardiovascular surgeons, endocrinologists, internists, nurses, undergraduate and graduate students in medicine and cell biology, and others interested in cardiovascular and metabolic medicine.
001476263 650_0 $$aCardiovascular system$$xDiseases.
001476263 650_0 $$aMetabolism$$xDisorders.
001476263 650_0 $$aExtracellular space.
001476263 650_0 $$aCell organelles.
001476263 650_0 $$aCytology.
001476263 655_0 $$aElectronic books.
001476263 7001_ $$aXiao, Junjie,$$d1983-
001476263 77608 $$iPrint version:$$aXiao, Junjie$$tExtracellular Vesicles in Cardiovascular and Metabolic Diseases$$dSingapore : Springer,c2023$$z9789819914425
001476263 830_0 $$aAdvances in experimental medicine and biology ;$$vv. 1418.
001476263 852__ $$bebk
001476263 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-981-99-1443-2$$zOnline Access$$91397441.1
001476263 909CO $$ooai:library.usi.edu:1476263$$pGLOBAL_SET
001476263 980__ $$aBIB
001476263 980__ $$aEBOOK
001476263 982__ $$aEbook
001476263 983__ $$aOnline
001476263 994__ $$a92$$bISE