High altitude medicine : a case-based approach / Jorge Hidalgo, Sabrina Da Re, António Gandra D'Almeida, editors.
Hidalgo, Jorge.; Da Re, Sabrina.; D'Almeida, António Gandra.
2023
RC103.M63
Available Online

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Title High altitude medicine : a case-based approach / Jorge Hidalgo, Sabrina Da Re, António Gandra D'Almeida, editors.
ISBN 9783031350924 (electronic bk.)
3031350928 (electronic bk.)
303135091X
9783031350917
DOI https://doi.org/10.1007/978-3-031-35092-4
Publication Details Cham : Springer, 2023.
Language English
Description 1 online resource
Item Number 10.1007/978-3-031-35092-4 doi
Call Number RC103.M63
Dewey Decimal Classification 616.9893
Summary High-altitude illness is a collective term for a cluster of acute clinical syndromes that directly consequence from rapid ascent to high altitude, viz., above 2500 m. The acute syndromes affecting the brain include acute mountain sickness (AMS) and high-altitude cerebral edema (HACE). The current practice of high altitude medicine requires a deep knowledge of existing evidence. However, knowledge of the field is continuously evolving, and there are many gaps in the existing literature as well as areas of controversy despite existing research in the area. Each chapter begins with a real case from the author's clinical practice. After each case, a question is asked to allow the reader to reflect on clinical management before reading the answer and consolidating knowledge from experts in the field. They also focus on the standard practice of management and diagnosis, emphasizing evidence-based care when available as well as areas of uncertainty and active debate in the medical literature. Written by experts in the field, High Altitude Medicine offers the most up-to-date knowledge about high altitude medicine that is not only useful for physicians at high altitude dedicated centers but also medical providers at different levels of their careers, especially emergency and urgent care physicians who are the ones that initially see the patient. .
Access Note Access limited to authorized users.
Source of Description Online resource; title from PDF title page (Springer, viewed September 14, 2023).
Added Author Hidalgo, Jorge.
Da Re, Sabrina.
D'Almeida, António Gandra.
Available in Other Form Print version: 9783031350917
Linked Resources Online Access
Record Appears in Online Resources > Ebooks
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Intro
Foreword
Acknowledgments
Contents
Chapter 1: Introduction to High Altitude Medicine
Objectives
Case Study
Discussion of the Case
Pathogeny
Clinic
AMS Clinic
HACE Clinic
HAPE Clinic
Diagnosis
AMS Diagnosis
HACE Diagnosis
HAPE Diagnosis
Differential Diagnosis (DD)
AMS DD
HACE DD
HAPE DD
Treatment
AMS and HACE Treatment
HAPE Treatment
Prevention
AMS/HACE Preventive
HAPE Preventive
Question Discussion
References
Chapter 2: History of High Altitude Medicine
HAPE
Introduction

History of High-Altitude Medicine
Soroche and Puna
Ballooning and High Altitude
Exploring the Everest
Conquering the Height Without Oxygen
The "Great and the Little Headache"
How Can You Identify with Acute Mountain Sickness Headache?
Conclusion
References
Chapter 3: Genetics in High Altitude Medicine
Case Scenario
Introduction
Role of Genetics in High Altitude Adaptation
Hypoxia Inducible Factor Pathway
Genes Identified in High Altitude Adaptations
Conclusion
References

Chapter 4: High Altitude Medicine, Its Relevance and Classification According to Meters
Introduction
Definition [3, 4]
Environment Considerations
References
Chapter 5: Physiology of High-Altitude Illness
Case Presentation
Principles of Hypobaric Hypoxia and Its Physiology
Overview
Acclimatization
Respiratory Changes
Renal Changes
Cardiovascular Changes
Hematologic Changes
Evidence Contour
Rate of Ascent
Preaclimatization
Alcohol, Sedative/Hypnotics, and Acclimatization
Diet and Altitude
Exercise
References

Chapter 6: Acid-Base Homeostasis at the High Altitude
Normal ABG Values at High Altitude
Acclimatization in Lowlanders Visiting High Altitudes
What If Acclimatization Is Inadequate?
Can Acid-Base Changes and Acclimatization Be Predicted?
References
Chapter 7: Cardiovascular Changes in High Altitude
Case Scenario
What Is the Diagnosis and Underlying Pathophysiology?
What Is Acute High Altitude Hypoxia (HAH) and the Cardiovascular Response?
The Cardiac System
The Pulmonary Vascular System
High Altitude Pulmonary Edema (HAPE)
The Cerebro-Vascular System

High Altitude Cerebral Edema (HACE)
What Are the Long Term Adaptations at High Altitude?
The Cardiac System
The Pulmonary Vascular System
Conclusion
References
Chapter 8: Peripheral Tissue in High Altitude
Introduction
Acute Adjustments
Acclimatization
Acclimatization to High Altitude
Systemic Circulation
Pulmonary Circulation
Cerebral Circulation
Hematopoietic Responses to Altitude
Oxyhemoglobin Dissociation Curve
Tissue Changes
Physiologic Changes during Acclimatization to Maintain Tissue Oxygen (O2) Delivery

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